The genotoxicity of particulate and soluble chromate in sperm whale (physeter macrocephalus) skin fibroblasts
Abstract Hexavalent chromium is a marine pollutant of concern, both for the health of ocean ecosystems and for public health. Hexavalent chromium is known to induce genotoxicity in human and other terrestrial mammals. It is also known to be present in both water and air in the marine environment. Ho...
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crwiley:10.1002/em.20579 2024-06-02T08:13:16+00:00 The genotoxicity of particulate and soluble chromate in sperm whale (physeter macrocephalus) skin fibroblasts Wise, John Pierce Wise, Sandra S. LaCerte, Carolyne Wise, John Pierce Aboueissa, AbouEl‐Makarim 2011 http://dx.doi.org/10.1002/em.20579 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fem.20579 https://onlinelibrary.wiley.com/doi/pdf/10.1002/em.20579 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Environmental and Molecular Mutagenesis volume 52, issue 1, page 43-49 ISSN 0893-6692 1098-2280 journal-article 2011 crwiley https://doi.org/10.1002/em.20579 2024-05-03T11:39:28Z Abstract Hexavalent chromium is a marine pollutant of concern, both for the health of ocean ecosystems and for public health. Hexavalent chromium is known to induce genotoxicity in human and other terrestrial mammals. It is also known to be present in both water and air in the marine environment. However, currently there are limited data concerning both chromium levels and its toxicological effects in marine mammals. This study investigated the cytotoxic and genotoxic effects of soluble and particulate hexavalent chromium in sperm whale skin fibroblasts. Both forms of hexavalent chromium induced concentration‐dependent increases in cytotoxicity and genotoxicity indicating that these compounds can be a health risk if the whales are exposed to them. These data support a hypothesis that chromium is a concern in the marine environment in general and for the health of sperm whales in particular. Environ. Mol. Mutagen. 52:43–49, 2011. © 2010 Wiley‐Liss, Inc. Article in Journal/Newspaper Physeter macrocephalus Sperm whale Wiley Online Library Environmental and Molecular Mutagenesis 52 1 43 49 |
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Wiley Online Library |
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crwiley |
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English |
description |
Abstract Hexavalent chromium is a marine pollutant of concern, both for the health of ocean ecosystems and for public health. Hexavalent chromium is known to induce genotoxicity in human and other terrestrial mammals. It is also known to be present in both water and air in the marine environment. However, currently there are limited data concerning both chromium levels and its toxicological effects in marine mammals. This study investigated the cytotoxic and genotoxic effects of soluble and particulate hexavalent chromium in sperm whale skin fibroblasts. Both forms of hexavalent chromium induced concentration‐dependent increases in cytotoxicity and genotoxicity indicating that these compounds can be a health risk if the whales are exposed to them. These data support a hypothesis that chromium is a concern in the marine environment in general and for the health of sperm whales in particular. Environ. Mol. Mutagen. 52:43–49, 2011. © 2010 Wiley‐Liss, Inc. |
format |
Article in Journal/Newspaper |
author |
Wise, John Pierce Wise, Sandra S. LaCerte, Carolyne Wise, John Pierce Aboueissa, AbouEl‐Makarim |
spellingShingle |
Wise, John Pierce Wise, Sandra S. LaCerte, Carolyne Wise, John Pierce Aboueissa, AbouEl‐Makarim The genotoxicity of particulate and soluble chromate in sperm whale (physeter macrocephalus) skin fibroblasts |
author_facet |
Wise, John Pierce Wise, Sandra S. LaCerte, Carolyne Wise, John Pierce Aboueissa, AbouEl‐Makarim |
author_sort |
Wise, John Pierce |
title |
The genotoxicity of particulate and soluble chromate in sperm whale (physeter macrocephalus) skin fibroblasts |
title_short |
The genotoxicity of particulate and soluble chromate in sperm whale (physeter macrocephalus) skin fibroblasts |
title_full |
The genotoxicity of particulate and soluble chromate in sperm whale (physeter macrocephalus) skin fibroblasts |
title_fullStr |
The genotoxicity of particulate and soluble chromate in sperm whale (physeter macrocephalus) skin fibroblasts |
title_full_unstemmed |
The genotoxicity of particulate and soluble chromate in sperm whale (physeter macrocephalus) skin fibroblasts |
title_sort |
genotoxicity of particulate and soluble chromate in sperm whale (physeter macrocephalus) skin fibroblasts |
publisher |
Wiley |
publishDate |
2011 |
url |
http://dx.doi.org/10.1002/em.20579 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fem.20579 https://onlinelibrary.wiley.com/doi/pdf/10.1002/em.20579 |
genre |
Physeter macrocephalus Sperm whale |
genre_facet |
Physeter macrocephalus Sperm whale |
op_source |
Environmental and Molecular Mutagenesis volume 52, issue 1, page 43-49 ISSN 0893-6692 1098-2280 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1002/em.20579 |
container_title |
Environmental and Molecular Mutagenesis |
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52 |
container_issue |
1 |
container_start_page |
43 |
op_container_end_page |
49 |
_version_ |
1800736716856754176 |