Transcriptome analysis provides new insights into cold adaptation of corsac fox ( Vulpes Corsac)
Abstract Vulpes are widely distributed throughout the world and have undergone drastic physiological and phenotypic changes in response to their environment. However, little is known about the underlying genetic causes of these traits, especially Vulpes corsac . In this study, RNA‐Seq was used to ob...
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Online Access: | http://dx.doi.org/10.1002/ece3.8866 https://onlinelibrary.wiley.com/doi/pdf/10.1002/ece3.8866 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/ece3.8866 |
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crwiley:10.1002/ece3.8866 2024-06-23T07:48:59+00:00 Transcriptome analysis provides new insights into cold adaptation of corsac fox ( Vulpes Corsac) Yang, Xiufeng Sun, Guolei Xia, Tian Cha, Muha Zhang, Lei Pang, Bo Tang, Qingming Dou, Huashan Zhang, Honghai National Natural Science Foundation of China 2022 http://dx.doi.org/10.1002/ece3.8866 https://onlinelibrary.wiley.com/doi/pdf/10.1002/ece3.8866 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/ece3.8866 en eng Wiley http://creativecommons.org/licenses/by/4.0/ Ecology and Evolution volume 12, issue 4 ISSN 2045-7758 2045-7758 journal-article 2022 crwiley https://doi.org/10.1002/ece3.8866 2024-05-31T08:15:11Z Abstract Vulpes are widely distributed throughout the world and have undergone drastic physiological and phenotypic changes in response to their environment. However, little is known about the underlying genetic causes of these traits, especially Vulpes corsac . In this study, RNA‐Seq was used to obtain a comprehensive dataset for multiple pooled tissues of corsac fox, and selection analysis of orthologous genes was performed to identify the genes that may be influenced by the low‐temperature environment. More than 6.32 Gb clean reads were obtained and assembled into a total of 173,353 unigenes with an average length of 557 bp for corsac fox. Selective pressure analysis showed that 16 positively selected genes (PSGs) were identified in corsac fox, red fox, and arctic fox. Enrichment analysis of PSGs showed that the LRP11 gene was enriched in several pathways related to the low‐temperature response and might play a key role in response to environmental stimuli of foxes. In addition, several positively selected genes were related to DNA damage repair ( ELP2 and CHAF1A ), innate immunity ( ARRDC4 and S100A12 ), and the respiratory chain ( NDUFA5 ), and these positively selected genes might play a role in adaptation to harsh wild fox environments. The results of common orthologous gene analysis showed that gene flow or convergent evolution might be an important factor in promoting regional differentiation of foxes. Our study provides a valuable transcriptomic resource for the evolutionary history of the corsac fox and the adaptations to the extreme environments. Article in Journal/Newspaper Arctic Fox Arctic Wiley Online Library Arctic Ecology and Evolution 12 4 |
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Wiley Online Library |
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English |
description |
Abstract Vulpes are widely distributed throughout the world and have undergone drastic physiological and phenotypic changes in response to their environment. However, little is known about the underlying genetic causes of these traits, especially Vulpes corsac . In this study, RNA‐Seq was used to obtain a comprehensive dataset for multiple pooled tissues of corsac fox, and selection analysis of orthologous genes was performed to identify the genes that may be influenced by the low‐temperature environment. More than 6.32 Gb clean reads were obtained and assembled into a total of 173,353 unigenes with an average length of 557 bp for corsac fox. Selective pressure analysis showed that 16 positively selected genes (PSGs) were identified in corsac fox, red fox, and arctic fox. Enrichment analysis of PSGs showed that the LRP11 gene was enriched in several pathways related to the low‐temperature response and might play a key role in response to environmental stimuli of foxes. In addition, several positively selected genes were related to DNA damage repair ( ELP2 and CHAF1A ), innate immunity ( ARRDC4 and S100A12 ), and the respiratory chain ( NDUFA5 ), and these positively selected genes might play a role in adaptation to harsh wild fox environments. The results of common orthologous gene analysis showed that gene flow or convergent evolution might be an important factor in promoting regional differentiation of foxes. Our study provides a valuable transcriptomic resource for the evolutionary history of the corsac fox and the adaptations to the extreme environments. |
author2 |
National Natural Science Foundation of China |
format |
Article in Journal/Newspaper |
author |
Yang, Xiufeng Sun, Guolei Xia, Tian Cha, Muha Zhang, Lei Pang, Bo Tang, Qingming Dou, Huashan Zhang, Honghai |
spellingShingle |
Yang, Xiufeng Sun, Guolei Xia, Tian Cha, Muha Zhang, Lei Pang, Bo Tang, Qingming Dou, Huashan Zhang, Honghai Transcriptome analysis provides new insights into cold adaptation of corsac fox ( Vulpes Corsac) |
author_facet |
Yang, Xiufeng Sun, Guolei Xia, Tian Cha, Muha Zhang, Lei Pang, Bo Tang, Qingming Dou, Huashan Zhang, Honghai |
author_sort |
Yang, Xiufeng |
title |
Transcriptome analysis provides new insights into cold adaptation of corsac fox ( Vulpes Corsac) |
title_short |
Transcriptome analysis provides new insights into cold adaptation of corsac fox ( Vulpes Corsac) |
title_full |
Transcriptome analysis provides new insights into cold adaptation of corsac fox ( Vulpes Corsac) |
title_fullStr |
Transcriptome analysis provides new insights into cold adaptation of corsac fox ( Vulpes Corsac) |
title_full_unstemmed |
Transcriptome analysis provides new insights into cold adaptation of corsac fox ( Vulpes Corsac) |
title_sort |
transcriptome analysis provides new insights into cold adaptation of corsac fox ( vulpes corsac) |
publisher |
Wiley |
publishDate |
2022 |
url |
http://dx.doi.org/10.1002/ece3.8866 https://onlinelibrary.wiley.com/doi/pdf/10.1002/ece3.8866 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/ece3.8866 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic Fox Arctic |
genre_facet |
Arctic Fox Arctic |
op_source |
Ecology and Evolution volume 12, issue 4 ISSN 2045-7758 2045-7758 |
op_rights |
http://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.1002/ece3.8866 |
container_title |
Ecology and Evolution |
container_volume |
12 |
container_issue |
4 |
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1802639274923786240 |