Investigating the role of genetic variation in vgll3 and six6 in the domestication of gilthead seabream ( Sparus aurata Linnaeus) and European seabass ( Dicentrarchus labrax Linnaeus)
Abstract Gene function conservation is crucial in molecular ecology, especially for key traits like growth and maturation in teleost fish. The vgll3 and six6 genes are known to influence age‐at‐maturity in Atlantic salmon, but their impact on other fish species is poorly understood. Here, we investi...
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Online Access: | http://dx.doi.org/10.1002/ece3.10727 https://onlinelibrary.wiley.com/doi/pdf/10.1002/ece3.10727 |
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crwiley:10.1002/ece3.10727 2024-09-15T17:56:31+00:00 Investigating the role of genetic variation in vgll3 and six6 in the domestication of gilthead seabream ( Sparus aurata Linnaeus) and European seabass ( Dicentrarchus labrax Linnaeus) Moulistanos, Aristotelis Nikolaou, Theopisti Sismanoglou, Smaragda Gkagkavouzis, Konstantinos Karaiskou, Nikoleta Antonopoulou, Efthimia Triantafyllidis, Alexandros Papakostas, Spiros Hellenic Foundation for Research and Innovation 2023 http://dx.doi.org/10.1002/ece3.10727 https://onlinelibrary.wiley.com/doi/pdf/10.1002/ece3.10727 en eng Wiley http://creativecommons.org/licenses/by/4.0/ Ecology and Evolution volume 13, issue 11 ISSN 2045-7758 2045-7758 journal-article 2023 crwiley https://doi.org/10.1002/ece3.10727 2024-08-06T04:21:13Z Abstract Gene function conservation is crucial in molecular ecology, especially for key traits like growth and maturation in teleost fish. The vgll3 and six6 genes are known to influence age‐at‐maturity in Atlantic salmon, but their impact on other fish species is poorly understood. Here, we investigated the association of vgll3 and six6 in the domestication of gilthead seabream and European seabass, both undergoing selective breeding for growth‐related traits in the Mediterranean. We analysed two different sets of samples using two different genotyping approaches. The first dataset comprised farmed and wild populations from Greece, genotyped for SNPs within the two genes (‘gene‐level genotyping’). The second dataset examined 300–600 k SNPs located in the chromosomes of the two genes, derived from a meta‐analysis of a Pool‐Seq experiment involving farmed and wild populations distributed widely across the Mediterranean (‘chromosome‐level genotyping’). The gene‐level analysis revealed a statistically significant allele frequency differences between farmed and wild populations on both genes in each species. This finding was partially supported by the chromosome‐level analysis, identifying highly differentiated regions may be involved in the domestication process at varying distances from the candidate genes. Noteworthy genomic features were found, such as a CpG island in gilthead seabream and novel candidate genes in European seabass, warranting further investigation. These findings support a putative role of vgll3 and six6 in the maturation and growth of gilthead seabream and European seabass, emphasizing the need for further research on their conserved function. Article in Journal/Newspaper Atlantic salmon Wiley Online Library Ecology and Evolution 13 11 |
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English |
description |
Abstract Gene function conservation is crucial in molecular ecology, especially for key traits like growth and maturation in teleost fish. The vgll3 and six6 genes are known to influence age‐at‐maturity in Atlantic salmon, but their impact on other fish species is poorly understood. Here, we investigated the association of vgll3 and six6 in the domestication of gilthead seabream and European seabass, both undergoing selective breeding for growth‐related traits in the Mediterranean. We analysed two different sets of samples using two different genotyping approaches. The first dataset comprised farmed and wild populations from Greece, genotyped for SNPs within the two genes (‘gene‐level genotyping’). The second dataset examined 300–600 k SNPs located in the chromosomes of the two genes, derived from a meta‐analysis of a Pool‐Seq experiment involving farmed and wild populations distributed widely across the Mediterranean (‘chromosome‐level genotyping’). The gene‐level analysis revealed a statistically significant allele frequency differences between farmed and wild populations on both genes in each species. This finding was partially supported by the chromosome‐level analysis, identifying highly differentiated regions may be involved in the domestication process at varying distances from the candidate genes. Noteworthy genomic features were found, such as a CpG island in gilthead seabream and novel candidate genes in European seabass, warranting further investigation. These findings support a putative role of vgll3 and six6 in the maturation and growth of gilthead seabream and European seabass, emphasizing the need for further research on their conserved function. |
author2 |
Hellenic Foundation for Research and Innovation |
format |
Article in Journal/Newspaper |
author |
Moulistanos, Aristotelis Nikolaou, Theopisti Sismanoglou, Smaragda Gkagkavouzis, Konstantinos Karaiskou, Nikoleta Antonopoulou, Efthimia Triantafyllidis, Alexandros Papakostas, Spiros |
spellingShingle |
Moulistanos, Aristotelis Nikolaou, Theopisti Sismanoglou, Smaragda Gkagkavouzis, Konstantinos Karaiskou, Nikoleta Antonopoulou, Efthimia Triantafyllidis, Alexandros Papakostas, Spiros Investigating the role of genetic variation in vgll3 and six6 in the domestication of gilthead seabream ( Sparus aurata Linnaeus) and European seabass ( Dicentrarchus labrax Linnaeus) |
author_facet |
Moulistanos, Aristotelis Nikolaou, Theopisti Sismanoglou, Smaragda Gkagkavouzis, Konstantinos Karaiskou, Nikoleta Antonopoulou, Efthimia Triantafyllidis, Alexandros Papakostas, Spiros |
author_sort |
Moulistanos, Aristotelis |
title |
Investigating the role of genetic variation in vgll3 and six6 in the domestication of gilthead seabream ( Sparus aurata Linnaeus) and European seabass ( Dicentrarchus labrax Linnaeus) |
title_short |
Investigating the role of genetic variation in vgll3 and six6 in the domestication of gilthead seabream ( Sparus aurata Linnaeus) and European seabass ( Dicentrarchus labrax Linnaeus) |
title_full |
Investigating the role of genetic variation in vgll3 and six6 in the domestication of gilthead seabream ( Sparus aurata Linnaeus) and European seabass ( Dicentrarchus labrax Linnaeus) |
title_fullStr |
Investigating the role of genetic variation in vgll3 and six6 in the domestication of gilthead seabream ( Sparus aurata Linnaeus) and European seabass ( Dicentrarchus labrax Linnaeus) |
title_full_unstemmed |
Investigating the role of genetic variation in vgll3 and six6 in the domestication of gilthead seabream ( Sparus aurata Linnaeus) and European seabass ( Dicentrarchus labrax Linnaeus) |
title_sort |
investigating the role of genetic variation in vgll3 and six6 in the domestication of gilthead seabream ( sparus aurata linnaeus) and european seabass ( dicentrarchus labrax linnaeus) |
publisher |
Wiley |
publishDate |
2023 |
url |
http://dx.doi.org/10.1002/ece3.10727 https://onlinelibrary.wiley.com/doi/pdf/10.1002/ece3.10727 |
genre |
Atlantic salmon |
genre_facet |
Atlantic salmon |
op_source |
Ecology and Evolution volume 13, issue 11 ISSN 2045-7758 2045-7758 |
op_rights |
http://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.1002/ece3.10727 |
container_title |
Ecology and Evolution |
container_volume |
13 |
container_issue |
11 |
_version_ |
1810432712250490880 |