Early embryonic expression of a 60‐kD glycoprotein in the developing nervous system of the lobster
Abstract To investigate the developmental processes that generate the crustacean nervous system, we used a monoclonal antibody that recognises an antigen that is expressed in the developing embryonic nervous system of the lobster, Homarus gammarus. Expression of this antigen commences early in embry...
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crwiley:10.1002/cne.903460409 2024-06-02T08:07:51+00:00 Early embryonic expression of a 60‐kD glycoprotein in the developing nervous system of the lobster Garzino, Veronique Reichert, Heinrich 1994 http://dx.doi.org/10.1002/cne.903460409 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fcne.903460409 https://onlinelibrary.wiley.com/doi/pdf/10.1002/cne.903460409 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Journal of Comparative Neurology volume 346, issue 4, page 572-582 ISSN 0021-9967 1096-9861 journal-article 1994 crwiley https://doi.org/10.1002/cne.903460409 2024-05-03T10:52:37Z Abstract To investigate the developmental processes that generate the crustacean nervous system, we used a monoclonal antibody that recognises an antigen that is expressed in the developing embryonic nervous system of the lobster, Homarus gammarus. Expression of this antigen commences early in embryogenesis, occurs in all parts of the embryonic central and peripheral nervous systems, and continues into adulthood. Initial expression in the central nervous system correlates with the onset of neuronal process outgrowth. Light microscopic analysis shows that the antigen is found surrounding the cell bodies and processes of all neurons. Biochemical analysis indicates that the antigen, is a glycoprotein with an apparent molecular weight of 60 kD. Due to the early embryonic onset of its expression, this antigen is a useful cellular label for visualisation of‐ pattern formation in the developing nervous system; this is documented in detail for the developing stomatogastric nervous system. The fact that the 60‐kD antigen is expressed early in embryogenesis throughout the nervous system suggests that it might play an important role in the development of the lobster nervous system. © 1994 Wiley‐Liss, Inc. Article in Journal/Newspaper Homarus gammarus Wiley Online Library Journal of Comparative Neurology 346 4 572 582 |
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Wiley Online Library |
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English |
description |
Abstract To investigate the developmental processes that generate the crustacean nervous system, we used a monoclonal antibody that recognises an antigen that is expressed in the developing embryonic nervous system of the lobster, Homarus gammarus. Expression of this antigen commences early in embryogenesis, occurs in all parts of the embryonic central and peripheral nervous systems, and continues into adulthood. Initial expression in the central nervous system correlates with the onset of neuronal process outgrowth. Light microscopic analysis shows that the antigen is found surrounding the cell bodies and processes of all neurons. Biochemical analysis indicates that the antigen, is a glycoprotein with an apparent molecular weight of 60 kD. Due to the early embryonic onset of its expression, this antigen is a useful cellular label for visualisation of‐ pattern formation in the developing nervous system; this is documented in detail for the developing stomatogastric nervous system. The fact that the 60‐kD antigen is expressed early in embryogenesis throughout the nervous system suggests that it might play an important role in the development of the lobster nervous system. © 1994 Wiley‐Liss, Inc. |
format |
Article in Journal/Newspaper |
author |
Garzino, Veronique Reichert, Heinrich |
spellingShingle |
Garzino, Veronique Reichert, Heinrich Early embryonic expression of a 60‐kD glycoprotein in the developing nervous system of the lobster |
author_facet |
Garzino, Veronique Reichert, Heinrich |
author_sort |
Garzino, Veronique |
title |
Early embryonic expression of a 60‐kD glycoprotein in the developing nervous system of the lobster |
title_short |
Early embryonic expression of a 60‐kD glycoprotein in the developing nervous system of the lobster |
title_full |
Early embryonic expression of a 60‐kD glycoprotein in the developing nervous system of the lobster |
title_fullStr |
Early embryonic expression of a 60‐kD glycoprotein in the developing nervous system of the lobster |
title_full_unstemmed |
Early embryonic expression of a 60‐kD glycoprotein in the developing nervous system of the lobster |
title_sort |
early embryonic expression of a 60‐kd glycoprotein in the developing nervous system of the lobster |
publisher |
Wiley |
publishDate |
1994 |
url |
http://dx.doi.org/10.1002/cne.903460409 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fcne.903460409 https://onlinelibrary.wiley.com/doi/pdf/10.1002/cne.903460409 |
genre |
Homarus gammarus |
genre_facet |
Homarus gammarus |
op_source |
Journal of Comparative Neurology volume 346, issue 4, page 572-582 ISSN 0021-9967 1096-9861 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1002/cne.903460409 |
container_title |
Journal of Comparative Neurology |
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346 |
container_issue |
4 |
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572 |
op_container_end_page |
582 |
_version_ |
1800752981156560896 |