Modeling of Process Operation Principles for the Immobilized Enzyme Candida Antarctica under Activity Decay
Abstract Environmentally friendly processes that use enzymatic catalysts are often affected by faster deactivation than their conventional catalyst competitors. An intelligent process design that increases the lifetime of the enzyme Candida Antarctica Lipase B in an epoxidation reaction is described...
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Online Access: | http://dx.doi.org/10.1002/cite.202100187 https://onlinelibrary.wiley.com/doi/pdf/10.1002/cite.202100187 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/cite.202100187 |
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crwiley:10.1002/cite.202100187 2024-06-02T07:58:34+00:00 Modeling of Process Operation Principles for the Immobilized Enzyme Candida Antarctica under Activity Decay Feigel, Matthias Hinrichsen, Olaf Bundesministerium für Bildung und Forschung 2022 http://dx.doi.org/10.1002/cite.202100187 https://onlinelibrary.wiley.com/doi/pdf/10.1002/cite.202100187 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/cite.202100187 en eng Wiley http://creativecommons.org/licenses/by/4.0/ Chemie Ingenieur Technik volume 94, issue 5, page 652-662 ISSN 0009-286X 1522-2640 journal-article 2022 crwiley https://doi.org/10.1002/cite.202100187 2024-05-03T11:31:57Z Abstract Environmentally friendly processes that use enzymatic catalysts are often affected by faster deactivation than their conventional catalyst competitors. An intelligent process design that increases the lifetime of the enzyme Candida Antarctica Lipase B in an epoxidation reaction is described. Employing this strategy could result in an advancement of the competitiveness of the cost‐intensive biological catalyst. With parallel fixed bed reactors operating in staggered mode and extended by an activity‐dependent volume flow control, the lifetime and productivity of the enzyme were significantly increased. The process strategy presented is not limited to the underlying reaction system but can be applied to similar processes facing a fast activity decay. Article in Journal/Newspaper Antarc* Antarctica Wiley Online Library Chemie Ingenieur Technik |
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Open Polar |
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Wiley Online Library |
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English |
description |
Abstract Environmentally friendly processes that use enzymatic catalysts are often affected by faster deactivation than their conventional catalyst competitors. An intelligent process design that increases the lifetime of the enzyme Candida Antarctica Lipase B in an epoxidation reaction is described. Employing this strategy could result in an advancement of the competitiveness of the cost‐intensive biological catalyst. With parallel fixed bed reactors operating in staggered mode and extended by an activity‐dependent volume flow control, the lifetime and productivity of the enzyme were significantly increased. The process strategy presented is not limited to the underlying reaction system but can be applied to similar processes facing a fast activity decay. |
author2 |
Bundesministerium für Bildung und Forschung |
format |
Article in Journal/Newspaper |
author |
Feigel, Matthias Hinrichsen, Olaf |
spellingShingle |
Feigel, Matthias Hinrichsen, Olaf Modeling of Process Operation Principles for the Immobilized Enzyme Candida Antarctica under Activity Decay |
author_facet |
Feigel, Matthias Hinrichsen, Olaf |
author_sort |
Feigel, Matthias |
title |
Modeling of Process Operation Principles for the Immobilized Enzyme Candida Antarctica under Activity Decay |
title_short |
Modeling of Process Operation Principles for the Immobilized Enzyme Candida Antarctica under Activity Decay |
title_full |
Modeling of Process Operation Principles for the Immobilized Enzyme Candida Antarctica under Activity Decay |
title_fullStr |
Modeling of Process Operation Principles for the Immobilized Enzyme Candida Antarctica under Activity Decay |
title_full_unstemmed |
Modeling of Process Operation Principles for the Immobilized Enzyme Candida Antarctica under Activity Decay |
title_sort |
modeling of process operation principles for the immobilized enzyme candida antarctica under activity decay |
publisher |
Wiley |
publishDate |
2022 |
url |
http://dx.doi.org/10.1002/cite.202100187 https://onlinelibrary.wiley.com/doi/pdf/10.1002/cite.202100187 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/cite.202100187 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_source |
Chemie Ingenieur Technik volume 94, issue 5, page 652-662 ISSN 0009-286X 1522-2640 |
op_rights |
http://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.1002/cite.202100187 |
container_title |
Chemie Ingenieur Technik |
_version_ |
1800741948064006144 |