Combining regio‐ and enantioselectivity of lipases for the preparation of ( R)‐4‐chloro‐2‐butanol
Abstract Preparation of 98% ee ( R )‐4‐chloro‐2‐butanol was carried out by the enzymatic hydrolysis of chlorohydrin esters, using fungal resting cells and commercial enzymes. Hydrolyzes were carried out using lipases from Candida antarctica (Novozym 435®), C. rugosa, Rhizomucor miehei (Lipozyme® IM)...
Published in: | Chirality |
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Main Authors: | , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wiley
2006
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Subjects: | |
Online Access: | http://dx.doi.org/10.1002/chir.20339 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchir.20339 https://onlinelibrary.wiley.com/doi/pdf/10.1002/chir.20339 |