ChemInform Abstract: The Preparation of Trisubstituted Alkenyl Nucleoside Phosphonates under Ultrasound‐Assisted Olefin Cross‐Metathesis.

Abstract Title compounds (III) undergo regioselective chemoenzymatic deacetylation.The best results are obtained with Candida antarctica lipase B to afford monoalcohol (IV) which reacts with various pyrimidine and purine derivatives under Mitsunobu conditions.

Bibliographic Details
Published in:ChemInform
Main Authors: Sari, Ozkan, Hamada, Manabu, Roy, Vincent, Nolan, Steven P., Agrofoglio, Luigi A.
Format: Article in Journal/Newspaper
Language:English
Published: Wiley 2014
Subjects:
Online Access:http://dx.doi.org/10.1002/chin.201405184
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchin.201405184
https://onlinelibrary.wiley.com/doi/pdf/10.1002/chin.201405184
Description
Summary:Abstract Title compounds (III) undergo regioselective chemoenzymatic deacetylation.The best results are obtained with Candida antarctica lipase B to afford monoalcohol (IV) which reacts with various pyrimidine and purine derivatives under Mitsunobu conditions.