Minor Enantiomer Recycling: Metal Catalyst, Organocatalyst and Biocatalyst Working in Concert

• Published in: Chemistry – A European Journal
• Main Authors: Wingstrand, Erica, Laurell, Anna, Fransson, Linda, Hult, Karl, Moberg, Christina
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 2009
• Subjects: Rugosa; Salen; Antarc*; Antarctica
• Online Access: http://dx.doi.org/10.1002/chem.200901338; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchem.200901338; https://onlinelibrary.wiley.com/doi/full/10.1002/chem.200901338

Abstract A minor enantiomer recycling one‐pot procedure employing two reinforcing chiral catalysts has been developed. Continuous regeneration of the achiral starting material is effected via selective enzyme‐catalyzed hydrolysis of the minor product enantiomer from Lewis acid–Lewis base catalyzed a...