Water as Cosolvent: Nonviscous Deep Eutectic Solvents for Efficient Lipase‐Catalyzed Esterifications
Abstract The use of deep eutectic solvent (DES)/water mixtures were explored for the selective enzymatic synthesis of α‐monobenzoate glycerol (α‐MBG) from glycerol and benzoic acid as substrates. Experiments were performed with four DES, three of them containing choline chloride (ChCl), combined wit...
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crwiley:10.1002/cctc.201601575 2024-06-23T07:46:13+00:00 Water as Cosolvent: Nonviscous Deep Eutectic Solvents for Efficient Lipase‐Catalyzed Esterifications Guajardo, Nadia Domínguez de María, Pablo Ahumada, Katherine Schrebler, Rodrigo A. Ramírez‐Tagle, Rodrigo Crespo, Fernando A. Carlesi, Carlos 2017 http://dx.doi.org/10.1002/cctc.201601575 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fcctc.201601575 https://onlinelibrary.wiley.com/doi/full/10.1002/cctc.201601575 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor ChemCatChem volume 9, issue 8, page 1393-1396 ISSN 1867-3880 1867-3899 journal-article 2017 crwiley https://doi.org/10.1002/cctc.201601575 2024-06-04T06:46:06Z Abstract The use of deep eutectic solvent (DES)/water mixtures were explored for the selective enzymatic synthesis of α‐monobenzoate glycerol (α‐MBG) from glycerol and benzoic acid as substrates. Experiments were performed with four DES, three of them containing choline chloride (ChCl), combined with urea (URA), glycerol (GLY), and ethylene glycol (ETA) (in all cases ChCl/HBD 1:2 mol ratio), and another one formed with methylammonium chloride and glycerol (MA/GLY 1:3 mol ratio). The best conversions (99 %) were achieved with immobilized lipase B from Candida antarctica (CAL‐B) when ChCl/GLY was used as the solvent and the substrate at the same time. The use of water as a cosolvent (8 % v / v ) led to a significant decrease in the viscosity of the DES, and full conversions were then reached. Reusability studies of the biocatalyst revealed a 37 % decrease in activity after the first batch, but the activity remained mostly constant for the rest of the cycles. Article in Journal/Newspaper Antarc* Antarctica Wiley Online Library Eta ENVELOPE(-62.917,-62.917,-64.300,-64.300) Ura ENVELOPE(6.679,6.679,62.600,62.600) ChemCatChem 9 8 1393 1396 |
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Wiley Online Library |
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crwiley |
language |
English |
description |
Abstract The use of deep eutectic solvent (DES)/water mixtures were explored for the selective enzymatic synthesis of α‐monobenzoate glycerol (α‐MBG) from glycerol and benzoic acid as substrates. Experiments were performed with four DES, three of them containing choline chloride (ChCl), combined with urea (URA), glycerol (GLY), and ethylene glycol (ETA) (in all cases ChCl/HBD 1:2 mol ratio), and another one formed with methylammonium chloride and glycerol (MA/GLY 1:3 mol ratio). The best conversions (99 %) were achieved with immobilized lipase B from Candida antarctica (CAL‐B) when ChCl/GLY was used as the solvent and the substrate at the same time. The use of water as a cosolvent (8 % v / v ) led to a significant decrease in the viscosity of the DES, and full conversions were then reached. Reusability studies of the biocatalyst revealed a 37 % decrease in activity after the first batch, but the activity remained mostly constant for the rest of the cycles. |
format |
Article in Journal/Newspaper |
author |
Guajardo, Nadia Domínguez de María, Pablo Ahumada, Katherine Schrebler, Rodrigo A. Ramírez‐Tagle, Rodrigo Crespo, Fernando A. Carlesi, Carlos |
spellingShingle |
Guajardo, Nadia Domínguez de María, Pablo Ahumada, Katherine Schrebler, Rodrigo A. Ramírez‐Tagle, Rodrigo Crespo, Fernando A. Carlesi, Carlos Water as Cosolvent: Nonviscous Deep Eutectic Solvents for Efficient Lipase‐Catalyzed Esterifications |
author_facet |
Guajardo, Nadia Domínguez de María, Pablo Ahumada, Katherine Schrebler, Rodrigo A. Ramírez‐Tagle, Rodrigo Crespo, Fernando A. Carlesi, Carlos |
author_sort |
Guajardo, Nadia |
title |
Water as Cosolvent: Nonviscous Deep Eutectic Solvents for Efficient Lipase‐Catalyzed Esterifications |
title_short |
Water as Cosolvent: Nonviscous Deep Eutectic Solvents for Efficient Lipase‐Catalyzed Esterifications |
title_full |
Water as Cosolvent: Nonviscous Deep Eutectic Solvents for Efficient Lipase‐Catalyzed Esterifications |
title_fullStr |
Water as Cosolvent: Nonviscous Deep Eutectic Solvents for Efficient Lipase‐Catalyzed Esterifications |
title_full_unstemmed |
Water as Cosolvent: Nonviscous Deep Eutectic Solvents for Efficient Lipase‐Catalyzed Esterifications |
title_sort |
water as cosolvent: nonviscous deep eutectic solvents for efficient lipase‐catalyzed esterifications |
publisher |
Wiley |
publishDate |
2017 |
url |
http://dx.doi.org/10.1002/cctc.201601575 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fcctc.201601575 https://onlinelibrary.wiley.com/doi/full/10.1002/cctc.201601575 |
long_lat |
ENVELOPE(-62.917,-62.917,-64.300,-64.300) ENVELOPE(6.679,6.679,62.600,62.600) |
geographic |
Eta Ura |
geographic_facet |
Eta Ura |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_source |
ChemCatChem volume 9, issue 8, page 1393-1396 ISSN 1867-3880 1867-3899 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1002/cctc.201601575 |
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ChemCatChem |
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9 |
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8 |
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1393 |
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1396 |
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1802644641874444288 |