Allosteric modulation of monomeric proteins*
Abstract Multimeric proteins ( e.g. hemoglobin) are considered to be the prototypes of allosteric enzymes, whereas monomeric proteins ( e.g. myoglobin) usually are assumed to be nonallosteric. However, the modulation of the functional properties of monomeric proteins by heterotropic allosteric effec...
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crwiley:10.1002/bmb.2005.494033032470 2024-09-15T18:37:32+00:00 Allosteric modulation of monomeric proteins* Ascenzi, Paolo Bocedi, Alessio Bolli, Alessandro Fasano, Mauro Notari, Stefania Polticelli, Fabio 2005 http://dx.doi.org/10.1002/bmb.2005.494033032470 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbmb.2005.494033032470 https://iubmb.onlinelibrary.wiley.com/doi/pdf/10.1002/bmb.2005.494033032470 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Biochemistry and Molecular Biology Education volume 33, issue 3, page 169-176 ISSN 1470-8175 1539-3429 journal-article 2005 crwiley https://doi.org/10.1002/bmb.2005.494033032470 2024-08-27T04:27:21Z Abstract Multimeric proteins ( e.g. hemoglobin) are considered to be the prototypes of allosteric enzymes, whereas monomeric proteins ( e.g. myoglobin) usually are assumed to be nonallosteric. However, the modulation of the functional properties of monomeric proteins by heterotropic allosteric effectors casts doubts on this assumption. Here, the allosteric properties of sperm whale myoglobin, human serum albumin, and human α‐thrombin, generally considered as molecular models of monomeric proteins, are summarized. Article in Journal/Newspaper Sperm whale Wiley Online Library Biochemistry and Molecular Biology Education 33 3 169 176 |
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Open Polar |
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Wiley Online Library |
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crwiley |
language |
English |
description |
Abstract Multimeric proteins ( e.g. hemoglobin) are considered to be the prototypes of allosteric enzymes, whereas monomeric proteins ( e.g. myoglobin) usually are assumed to be nonallosteric. However, the modulation of the functional properties of monomeric proteins by heterotropic allosteric effectors casts doubts on this assumption. Here, the allosteric properties of sperm whale myoglobin, human serum albumin, and human α‐thrombin, generally considered as molecular models of monomeric proteins, are summarized. |
format |
Article in Journal/Newspaper |
author |
Ascenzi, Paolo Bocedi, Alessio Bolli, Alessandro Fasano, Mauro Notari, Stefania Polticelli, Fabio |
spellingShingle |
Ascenzi, Paolo Bocedi, Alessio Bolli, Alessandro Fasano, Mauro Notari, Stefania Polticelli, Fabio Allosteric modulation of monomeric proteins* |
author_facet |
Ascenzi, Paolo Bocedi, Alessio Bolli, Alessandro Fasano, Mauro Notari, Stefania Polticelli, Fabio |
author_sort |
Ascenzi, Paolo |
title |
Allosteric modulation of monomeric proteins* |
title_short |
Allosteric modulation of monomeric proteins* |
title_full |
Allosteric modulation of monomeric proteins* |
title_fullStr |
Allosteric modulation of monomeric proteins* |
title_full_unstemmed |
Allosteric modulation of monomeric proteins* |
title_sort |
allosteric modulation of monomeric proteins* |
publisher |
Wiley |
publishDate |
2005 |
url |
http://dx.doi.org/10.1002/bmb.2005.494033032470 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbmb.2005.494033032470 https://iubmb.onlinelibrary.wiley.com/doi/pdf/10.1002/bmb.2005.494033032470 |
genre |
Sperm whale |
genre_facet |
Sperm whale |
op_source |
Biochemistry and Molecular Biology Education volume 33, issue 3, page 169-176 ISSN 1470-8175 1539-3429 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1002/bmb.2005.494033032470 |
container_title |
Biochemistry and Molecular Biology Education |
container_volume |
33 |
container_issue |
3 |
container_start_page |
169 |
op_container_end_page |
176 |
_version_ |
1810481910073262080 |