Movements at the hemoglobin A‐hemes and their role in ligand binding, analyzed by X‐ray crystallography

• Published in: Biopolymers
• Main Authors: Dodson, Eleanor, Dodson, Guy
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 2009
• Subjects: Antarctic; The Antarctic; Bolton; Perutz; Antarc*
• Online Access: http://dx.doi.org/10.1002/bip.21197; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbip.21197; https://onlinelibrary.wiley.com/doi/pdf/10.1002/bip.21197

Abstract The two hemoglobin structures determined by Max Perutz, the liganded R‐state, which has high oxygen affinity, and the unliganded T‐state with low oxygen affinity, were landmarks in molecular and structural biology (Perutz and Lehman, Nature 1968, 219, 902–909; Bolton and Perutz, Nature 1970...