BioEssays 8/2012
Immunological insights from fish. Among vertebrates, teleosts comprise particularly diverse and ancient lineages that can provide alternative immunological solutions to biological and environmental challenges. For example, Atlantic cod is the first species reported that has lost the major histocompa...
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Online Access: | http://dx.doi.org/10.1002/bies.201290036 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbies.201290036 https://onlinelibrary.wiley.com/doi/pdf/10.1002/bies.201290036 |
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crwiley:10.1002/bies.201290036 2024-06-02T08:03:11+00:00 BioEssays 8/2012 2012 http://dx.doi.org/10.1002/bies.201290036 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbies.201290036 https://onlinelibrary.wiley.com/doi/pdf/10.1002/bies.201290036 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor BioEssays volume 34, issue 8 ISSN 0265-9247 1521-1878 journal-article 2012 crwiley https://doi.org/10.1002/bies.201290036 2024-05-03T12:06:52Z Immunological insights from fish. Among vertebrates, teleosts comprise particularly diverse and ancient lineages that can provide alternative immunological solutions to biological and environmental challenges. For example, Atlantic cod is the first species reported that has lost the major histocompatibility complex (MHC) II, one of the antigen presentation systems previously believed to be conserved among all jawed vertebrates, and this loss coincides with a distinct immune gene repertoire. In this issue (pages 648–651 ), Star and Jentoft propose several scenarios, with different selective assumptions, that may have lead to the emergence of these phenomena. Through comparative studies of immune genes in multiple teleost lineages, we may be able to infer a causal link between the loss of MHC II and the emergence of such distinct immune gene repertoire. Additionally, these studies can identify which biological and environmental factors have promoted their evolution and provide a deeper understanding of the selective processes that have affected the vertebrate immune system. Article in Journal/Newspaper atlantic cod Wiley Online Library BioEssays 34 8 |
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Immunological insights from fish. Among vertebrates, teleosts comprise particularly diverse and ancient lineages that can provide alternative immunological solutions to biological and environmental challenges. For example, Atlantic cod is the first species reported that has lost the major histocompatibility complex (MHC) II, one of the antigen presentation systems previously believed to be conserved among all jawed vertebrates, and this loss coincides with a distinct immune gene repertoire. In this issue (pages 648–651 ), Star and Jentoft propose several scenarios, with different selective assumptions, that may have lead to the emergence of these phenomena. Through comparative studies of immune genes in multiple teleost lineages, we may be able to infer a causal link between the loss of MHC II and the emergence of such distinct immune gene repertoire. Additionally, these studies can identify which biological and environmental factors have promoted their evolution and provide a deeper understanding of the selective processes that have affected the vertebrate immune system. |
format |
Article in Journal/Newspaper |
title |
BioEssays 8/2012 |
spellingShingle |
BioEssays 8/2012 |
title_short |
BioEssays 8/2012 |
title_full |
BioEssays 8/2012 |
title_fullStr |
BioEssays 8/2012 |
title_full_unstemmed |
BioEssays 8/2012 |
title_sort |
bioessays 8/2012 |
publisher |
Wiley |
publishDate |
2012 |
url |
http://dx.doi.org/10.1002/bies.201290036 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbies.201290036 https://onlinelibrary.wiley.com/doi/pdf/10.1002/bies.201290036 |
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atlantic cod |
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atlantic cod |
op_source |
BioEssays volume 34, issue 8 ISSN 0265-9247 1521-1878 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1002/bies.201290036 |
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BioEssays |
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34 |
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8 |
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1800747657155575808 |