mtDNA variation in Inuit populations of Greenland and Canada: Migration history and population structure
Abstract We examined 395 mtDNA control‐region sequences from Greenlandic Inuit and Canadian Kitikmeot Inuit with the aim of shedding light on the migration history that underlies the present geographic patterns of genetic variation at this locus in the Arctic. In line with previous studies, we found...
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crwiley:10.1002/ajpa.20313 2024-03-17T08:56:02+00:00 mtDNA variation in Inuit populations of Greenland and Canada: Migration history and population structure Helgason, Agnar Pálsson, Gísli Pedersen, Henning Sloth Angulalik, Emily Gunnarsdóttir, Ellen Dröfn Yngvadóttir, Bryndís Stefánsson, Kári 2005 http://dx.doi.org/10.1002/ajpa.20313 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fajpa.20313 https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajpa.20313 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor American Journal of Physical Anthropology volume 130, issue 1, page 123-134 ISSN 0002-9483 1096-8644 Anthropology Anatomy journal-article 2005 crwiley https://doi.org/10.1002/ajpa.20313 2024-02-22T01:07:19Z Abstract We examined 395 mtDNA control‐region sequences from Greenlandic Inuit and Canadian Kitikmeot Inuit with the aim of shedding light on the migration history that underlies the present geographic patterns of genetic variation at this locus in the Arctic. In line with previous studies, we found that Inuit populations carry only sequences belonging to haplotype clusters A2 and D3. However, a comparison of Arctic populations from Siberia, Canada, and Greenland revealed considerable differences in the frequencies of these haplotypes. Moreover, large sample sizes and regional information about birthplaces of maternal grandmothers permitted the detection of notable differences in the distribution of haplotypes among subpopulations within Greenland. Our results cast doubt on the prevailing hypothesis that contemporary Inuit trace their all of their ancestry to so‐called Thule groups that expanded from Alaska about 800–1,000 years ago. In particular, discrepancies in mutational divergence between the Inuit populations and their putative source mtDNA pool in Siberia/Alaska for the two predominant haplotype clusters, A2a and A2b, are more consistent with the possibility that expanding Thule groups encountered and interbred with existing Dorset populations in Canada and Greenland. Am J Phys Anthropol, 2006. © 2005 Wiley‐Liss, Inc. Article in Journal/Newspaper Arctic Greenland greenlandic inuit Kitikmeot Thule Alaska Siberia Wiley Online Library Arctic Canada Greenland American Journal of Physical Anthropology 130 1 123 134 |
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collection |
Wiley Online Library |
op_collection_id |
crwiley |
language |
English |
topic |
Anthropology Anatomy |
spellingShingle |
Anthropology Anatomy Helgason, Agnar Pálsson, Gísli Pedersen, Henning Sloth Angulalik, Emily Gunnarsdóttir, Ellen Dröfn Yngvadóttir, Bryndís Stefánsson, Kári mtDNA variation in Inuit populations of Greenland and Canada: Migration history and population structure |
topic_facet |
Anthropology Anatomy |
description |
Abstract We examined 395 mtDNA control‐region sequences from Greenlandic Inuit and Canadian Kitikmeot Inuit with the aim of shedding light on the migration history that underlies the present geographic patterns of genetic variation at this locus in the Arctic. In line with previous studies, we found that Inuit populations carry only sequences belonging to haplotype clusters A2 and D3. However, a comparison of Arctic populations from Siberia, Canada, and Greenland revealed considerable differences in the frequencies of these haplotypes. Moreover, large sample sizes and regional information about birthplaces of maternal grandmothers permitted the detection of notable differences in the distribution of haplotypes among subpopulations within Greenland. Our results cast doubt on the prevailing hypothesis that contemporary Inuit trace their all of their ancestry to so‐called Thule groups that expanded from Alaska about 800–1,000 years ago. In particular, discrepancies in mutational divergence between the Inuit populations and their putative source mtDNA pool in Siberia/Alaska for the two predominant haplotype clusters, A2a and A2b, are more consistent with the possibility that expanding Thule groups encountered and interbred with existing Dorset populations in Canada and Greenland. Am J Phys Anthropol, 2006. © 2005 Wiley‐Liss, Inc. |
format |
Article in Journal/Newspaper |
author |
Helgason, Agnar Pálsson, Gísli Pedersen, Henning Sloth Angulalik, Emily Gunnarsdóttir, Ellen Dröfn Yngvadóttir, Bryndís Stefánsson, Kári |
author_facet |
Helgason, Agnar Pálsson, Gísli Pedersen, Henning Sloth Angulalik, Emily Gunnarsdóttir, Ellen Dröfn Yngvadóttir, Bryndís Stefánsson, Kári |
author_sort |
Helgason, Agnar |
title |
mtDNA variation in Inuit populations of Greenland and Canada: Migration history and population structure |
title_short |
mtDNA variation in Inuit populations of Greenland and Canada: Migration history and population structure |
title_full |
mtDNA variation in Inuit populations of Greenland and Canada: Migration history and population structure |
title_fullStr |
mtDNA variation in Inuit populations of Greenland and Canada: Migration history and population structure |
title_full_unstemmed |
mtDNA variation in Inuit populations of Greenland and Canada: Migration history and population structure |
title_sort |
mtdna variation in inuit populations of greenland and canada: migration history and population structure |
publisher |
Wiley |
publishDate |
2005 |
url |
http://dx.doi.org/10.1002/ajpa.20313 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fajpa.20313 https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajpa.20313 |
geographic |
Arctic Canada Greenland |
geographic_facet |
Arctic Canada Greenland |
genre |
Arctic Greenland greenlandic inuit Kitikmeot Thule Alaska Siberia |
genre_facet |
Arctic Greenland greenlandic inuit Kitikmeot Thule Alaska Siberia |
op_source |
American Journal of Physical Anthropology volume 130, issue 1, page 123-134 ISSN 0002-9483 1096-8644 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1002/ajpa.20313 |
container_title |
American Journal of Physical Anthropology |
container_volume |
130 |
container_issue |
1 |
container_start_page |
123 |
op_container_end_page |
134 |
_version_ |
1793764761969623040 |