Global Prevalence of Spondyloarthritis: A Systematic Review and Meta‐Regression Analysis
Objective To summarize the prevalence of spondyloarthritis (SpA) and its subtypes in the general population, and to identify demographic and methodologic characteristics that might explain heterogeneity in prevalence estimates. Methods A systematic literature search was performed to identify relevan...
Published in: | Arthritis Care & Research |
---|---|
Main Authors: | , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wiley
2016
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1002/acr.22831 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Facr.22831 http://onlinelibrary.wiley.com/wol1/doi/10.1002/acr.22831/fullpdf |
id |
crwiley:10.1002/acr.22831 |
---|---|
record_format |
openpolar |
spelling |
crwiley:10.1002/acr.22831 2024-06-23T07:50:16+00:00 Global Prevalence of Spondyloarthritis: A Systematic Review and Meta‐Regression Analysis Stolwijk, Carmen van Onna, Marloes Boonen, Annelies van Tubergen, Astrid 2016 http://dx.doi.org/10.1002/acr.22831 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Facr.22831 http://onlinelibrary.wiley.com/wol1/doi/10.1002/acr.22831/fullpdf en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Arthritis Care & Research volume 68, issue 9, page 1320-1331 ISSN 2151-464X 2151-4658 journal-article 2016 crwiley https://doi.org/10.1002/acr.22831 2024-06-11T04:42:14Z Objective To summarize the prevalence of spondyloarthritis (SpA) and its subtypes in the general population, and to identify demographic and methodologic characteristics that might explain heterogeneity in prevalence estimates. Methods A systematic literature search was performed to identify relevant articles. Risk of bias was assessed and data were extracted. Pooled prevalences were calculated. Potential sources of heterogeneity were explored by subgroup analysis and meta‐regression analysis. Results The prevalence of SpA ranged from 0.20% (95% confidence interval [95% CI] 0.00–0.66) in South‐East Asia to 1.61% (95% CI 1.27–2.00) in Northern Arctic communities; the prevalence of ankylosing spondylitis (AS) from 0.02% (95% CI 0.00–0.21) in Sub‐Saharan Africa to 0.35% (95% CI 0.24–0.48) in Northern Arctic communities; and the prevalence of psoriatic arthritis (PsA) from 0.01% (95% CI 0.00–0.17) in the Middle East to 0.19% (95% CI 0.16–0.32) in Europe. The following characteristics were significantly associated with variation in prevalence of SpA, AS, and/or PsA: proportion of females, mean age of the sample, geographic area and setting (demographic characteristics), year of data collection, case finding, and case ascertainment (methodologic characteristics). For the other SpA subgroups, too few studies were available to conduct a meta‐analysis, but prevalence estimates of reactive arthritis (range 0.0–0.2%), SpA related to inflammatory bowel disease (range 0.0–0.1%), and undifferentiated SpA (range 0.0–0.7%) were generally low. Conclusion SpA is a common disease, but with large variation in reported prevalence estimates, which can partly be explained by differences in demographic and methodologic characteristics. Particularly, geographic area as well as case finding account for a substantial part of the heterogeneity. Article in Journal/Newspaper Arctic Wiley Online Library Arctic Arthritis Care & Research 68 9 1320 1331 |
institution |
Open Polar |
collection |
Wiley Online Library |
op_collection_id |
crwiley |
language |
English |
description |
Objective To summarize the prevalence of spondyloarthritis (SpA) and its subtypes in the general population, and to identify demographic and methodologic characteristics that might explain heterogeneity in prevalence estimates. Methods A systematic literature search was performed to identify relevant articles. Risk of bias was assessed and data were extracted. Pooled prevalences were calculated. Potential sources of heterogeneity were explored by subgroup analysis and meta‐regression analysis. Results The prevalence of SpA ranged from 0.20% (95% confidence interval [95% CI] 0.00–0.66) in South‐East Asia to 1.61% (95% CI 1.27–2.00) in Northern Arctic communities; the prevalence of ankylosing spondylitis (AS) from 0.02% (95% CI 0.00–0.21) in Sub‐Saharan Africa to 0.35% (95% CI 0.24–0.48) in Northern Arctic communities; and the prevalence of psoriatic arthritis (PsA) from 0.01% (95% CI 0.00–0.17) in the Middle East to 0.19% (95% CI 0.16–0.32) in Europe. The following characteristics were significantly associated with variation in prevalence of SpA, AS, and/or PsA: proportion of females, mean age of the sample, geographic area and setting (demographic characteristics), year of data collection, case finding, and case ascertainment (methodologic characteristics). For the other SpA subgroups, too few studies were available to conduct a meta‐analysis, but prevalence estimates of reactive arthritis (range 0.0–0.2%), SpA related to inflammatory bowel disease (range 0.0–0.1%), and undifferentiated SpA (range 0.0–0.7%) were generally low. Conclusion SpA is a common disease, but with large variation in reported prevalence estimates, which can partly be explained by differences in demographic and methodologic characteristics. Particularly, geographic area as well as case finding account for a substantial part of the heterogeneity. |
format |
Article in Journal/Newspaper |
author |
Stolwijk, Carmen van Onna, Marloes Boonen, Annelies van Tubergen, Astrid |
spellingShingle |
Stolwijk, Carmen van Onna, Marloes Boonen, Annelies van Tubergen, Astrid Global Prevalence of Spondyloarthritis: A Systematic Review and Meta‐Regression Analysis |
author_facet |
Stolwijk, Carmen van Onna, Marloes Boonen, Annelies van Tubergen, Astrid |
author_sort |
Stolwijk, Carmen |
title |
Global Prevalence of Spondyloarthritis: A Systematic Review and Meta‐Regression Analysis |
title_short |
Global Prevalence of Spondyloarthritis: A Systematic Review and Meta‐Regression Analysis |
title_full |
Global Prevalence of Spondyloarthritis: A Systematic Review and Meta‐Regression Analysis |
title_fullStr |
Global Prevalence of Spondyloarthritis: A Systematic Review and Meta‐Regression Analysis |
title_full_unstemmed |
Global Prevalence of Spondyloarthritis: A Systematic Review and Meta‐Regression Analysis |
title_sort |
global prevalence of spondyloarthritis: a systematic review and meta‐regression analysis |
publisher |
Wiley |
publishDate |
2016 |
url |
http://dx.doi.org/10.1002/acr.22831 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Facr.22831 http://onlinelibrary.wiley.com/wol1/doi/10.1002/acr.22831/fullpdf |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Arthritis Care & Research volume 68, issue 9, page 1320-1331 ISSN 2151-464X 2151-4658 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1002/acr.22831 |
container_title |
Arthritis Care & Research |
container_volume |
68 |
container_issue |
9 |
container_start_page |
1320 |
op_container_end_page |
1331 |
_version_ |
1802641136823566336 |