High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010–2020
Abstract The Faroese population isolate harbors epidemiological and genetic characteristics that likely differ from outbred populations. This population‐based register study found that the Faroese 2010–2020 crude incidence of amyotrophic lateral sclerosis (ALS) was 4.9/100,000 person‐years (95% conf...
Published in: | Annals of Clinical and Translational Neurology |
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Online Access: | http://dx.doi.org/10.1002/acn3.51501 https://onlinelibrary.wiley.com/doi/pdf/10.1002/acn3.51501 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/acn3.51501 |
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crwiley:10.1002/acn3.51501 2024-06-23T07:52:38+00:00 High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010–2020 Johansen, Malan Svenstrup, Kirsten Joensen, Poul Steig, Bjarni á Andorsdóttir, Guðrið Hansen, Torben Petersen, Maria Skaalum Aage og Johanne Louis-Hansens Fond Minister Erna Hamiltons Legat for Videnskab og Kunst 2022 http://dx.doi.org/10.1002/acn3.51501 https://onlinelibrary.wiley.com/doi/pdf/10.1002/acn3.51501 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/acn3.51501 en eng Wiley http://creativecommons.org/licenses/by-nc-nd/4.0/ Annals of Clinical and Translational Neurology volume 9, issue 2, page 227-231 ISSN 2328-9503 2328-9503 journal-article 2022 crwiley https://doi.org/10.1002/acn3.51501 2024-06-11T04:42:28Z Abstract The Faroese population isolate harbors epidemiological and genetic characteristics that likely differ from outbred populations. This population‐based register study found that the Faroese 2010–2020 crude incidence of amyotrophic lateral sclerosis (ALS) was 4.9/100,000 person‐years (95% confidence interval [CI], 3.3–7.0) and the age‐ and sex‐standardized incidence (US 2010 Census Population) was 4.1/100,000 person‐years (95% CI, 2.7–6.0), which is a 68% increase from the 1987–2009 estimate. The 2020 crude prevalence was 9.5/100,000 (95% CI, 3.0–19.6) in a population of 52,912 inhabitants. Incidence and prevalence estimates of ALS in the Faroes are high and further research is warranted to uncover the genetic or environmental determinants of ALS in this population. Article in Journal/Newspaper Faroe Islands Faroes Wiley Online Library Faroe Islands Annals of Clinical and Translational Neurology 9 2 227 231 |
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description |
Abstract The Faroese population isolate harbors epidemiological and genetic characteristics that likely differ from outbred populations. This population‐based register study found that the Faroese 2010–2020 crude incidence of amyotrophic lateral sclerosis (ALS) was 4.9/100,000 person‐years (95% confidence interval [CI], 3.3–7.0) and the age‐ and sex‐standardized incidence (US 2010 Census Population) was 4.1/100,000 person‐years (95% CI, 2.7–6.0), which is a 68% increase from the 1987–2009 estimate. The 2020 crude prevalence was 9.5/100,000 (95% CI, 3.0–19.6) in a population of 52,912 inhabitants. Incidence and prevalence estimates of ALS in the Faroes are high and further research is warranted to uncover the genetic or environmental determinants of ALS in this population. |
author2 |
Aage og Johanne Louis-Hansens Fond Minister Erna Hamiltons Legat for Videnskab og Kunst |
format |
Article in Journal/Newspaper |
author |
Johansen, Malan Svenstrup, Kirsten Joensen, Poul Steig, Bjarni á Andorsdóttir, Guðrið Hansen, Torben Petersen, Maria Skaalum |
spellingShingle |
Johansen, Malan Svenstrup, Kirsten Joensen, Poul Steig, Bjarni á Andorsdóttir, Guðrið Hansen, Torben Petersen, Maria Skaalum High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010–2020 |
author_facet |
Johansen, Malan Svenstrup, Kirsten Joensen, Poul Steig, Bjarni á Andorsdóttir, Guðrið Hansen, Torben Petersen, Maria Skaalum |
author_sort |
Johansen, Malan |
title |
High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010–2020 |
title_short |
High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010–2020 |
title_full |
High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010–2020 |
title_fullStr |
High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010–2020 |
title_full_unstemmed |
High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010–2020 |
title_sort |
high incidence of amyotrophic lateral sclerosis in the faroe islands 2010–2020 |
publisher |
Wiley |
publishDate |
2022 |
url |
http://dx.doi.org/10.1002/acn3.51501 https://onlinelibrary.wiley.com/doi/pdf/10.1002/acn3.51501 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/acn3.51501 |
geographic |
Faroe Islands |
geographic_facet |
Faroe Islands |
genre |
Faroe Islands Faroes |
genre_facet |
Faroe Islands Faroes |
op_source |
Annals of Clinical and Translational Neurology volume 9, issue 2, page 227-231 ISSN 2328-9503 2328-9503 |
op_rights |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
op_doi |
https://doi.org/10.1002/acn3.51501 |
container_title |
Annals of Clinical and Translational Neurology |
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9 |
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2 |
container_start_page |
227 |
op_container_end_page |
231 |
_version_ |
1802644003590504448 |