Complement C3 Polymorphism In Greenland Eskimos
The C3F gene has been associated with atherosclerotic vascular disease. Greenland Eskimos have a very low frequency of acute myocardial infarction (AMI). The C3 polymorphism phenotypes were therefore determined by high-voltage agarose gel electrophoresis in 125 Greenland Eskimos originating from dif...
| Published in: | Thrombosis and Haemostasis, Oral Presentations |
|---|---|
| Main Authors: | , , , |
| Format: | Conference Object |
| Language: | unknown |
| Published: |
Schattauer GmbH
1981
|
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1055/s-0038-1652720 http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0038-1652720.pdf |
| Summary: | The C3F gene has been associated with atherosclerotic vascular disease. Greenland Eskimos have a very low frequency of acute myocardial infarction (AMI). The C3 polymorphism phenotypes were therefore determined by high-voltage agarose gel electrophoresis in 125 Greenland Eskimos originating from different parts of Greenland and compared with a control group of 1,554 Caucasian Danes. p The C3F gene frequency in the Eskimos (0.056) was significantly lower (p <0.001) than in the control Danes (0.201). These results indicate that genetical factors may also play a role for the low AMI frequency seen in Greenland Eskimos. |
|---|