Genetics of canine subvalvular aortic stenosis (SAS)

• Published in: Canine Medicine and Genetics
• Main Authors: Ontiveros, Eric S., Stern, Joshua A.
• Other Authors: American Kennel Club Canine Health Foundation
• Format: Article in Journal/Newspaper
• Language: English
• Published: Springer Science and Business Media LLC 2021
• Subjects: General Medicine; Bouvier; Flandres; Newfoundland
• Online Access: http://dx.doi.org/10.1186/s40575-021-00103-4; https://link.springer.com/content/pdf/10.1186/s40575-021-00103-4.pdf; https://link.springer.com/article/10.1186/s40575-021-00103-4/fulltext.html

Abstract Subvalvular aortic stenosis (SAS) is one of the most common congenital heart defects of dogs. The disease is characterized by obstruction of the left ventricular outflow tract, resulting in pressure overload on the left ventricle. The etiology of obstruction is a fibromuscular nodule, ridge...