The potential of pharmacological activities of the multi-compound treatment for GERD: literature review and a network pharmacology-based analysis

• Published in: Applied Biological Chemistry
• Main Authors: Park, Junghyun, Jang, Dongyeop, Phung, Hung Manh, Choi, Tae Joon, Kim, Chang-Eop, Lee, Sanghyun, Kang, Ki Sung, Choi, Seo-Hyung
• Other Authors: National Research Foundation of Korea, Gachon University
• Format: Article in Journal/Newspaper
• Language: English
• Published: Springer Science and Business Media LLC 2021
• Subjects: Organic Chemistry; General Biochemistry, Genetics and Molecular Biology; Georgi; Gerd; Crassostrea gigas
• Online Access: http://dx.doi.org/10.1186/s13765-021-00617-2; https://link.springer.com/content/pdf/10.1186/s13765-021-00617-2.pdf; https://link.springer.com/article/10.1186/s13765-021-00617-2/fulltext.html

Abstract The prevalence of gastroesophageal reflux disease (GERD) is rapidly increasing due to the adoption of a Westernized lifestyle; at the same time, safe and efficient treatment is required due to the side effects and refractoriness of proton pump inhibitors (PPIs). The frequently used multi-co...