Ambient nitrogen dioxide is associated with emergency hospital visits for atrial fibrillation: a population-based case-crossover study in Reykjavik, Iceland
Abstract Background In Iceland air quality is generally good; however, previous studies indicate that there is an association between air pollution in Reykjavik and adverse health effects as measured by dispensing of medications, mortality, and increase in health care utilisation. The aim was to stu...
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Springer Science and Business Media LLC
2022
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Online Access: | http://dx.doi.org/10.1186/s12940-021-00817-9 https://link.springer.com/content/pdf/10.1186/s12940-021-00817-9.pdf https://link.springer.com/article/10.1186/s12940-021-00817-9/fulltext.html |
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crspringernat:10.1186/s12940-021-00817-9 2023-05-15T16:48:29+02:00 Ambient nitrogen dioxide is associated with emergency hospital visits for atrial fibrillation: a population-based case-crossover study in Reykjavik, Iceland Halldorsdottir, Solveig Finnbjornsdottir, Ragnhildur Gudrun Elvarsson, Bjarki Thor Gudmundsson, Gunnar Rafnsson, Vilhjalmur 2022 http://dx.doi.org/10.1186/s12940-021-00817-9 https://link.springer.com/content/pdf/10.1186/s12940-021-00817-9.pdf https://link.springer.com/article/10.1186/s12940-021-00817-9/fulltext.html en eng Springer Science and Business Media LLC https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 CC-BY Environmental Health volume 21, issue 1 ISSN 1476-069X Health, Toxicology and Mutagenesis Public Health, Environmental and Occupational Health journal-article 2022 crspringernat https://doi.org/10.1186/s12940-021-00817-9 2022-01-14T15:37:31Z Abstract Background In Iceland air quality is generally good; however, previous studies indicate that there is an association between air pollution in Reykjavik and adverse health effects as measured by dispensing of medications, mortality, and increase in health care utilisation. The aim was to study the association between traffic-related ambient air pollution in the Reykjavik capital area and emergency hospital visits for heart diseases and particularly atrial fibrillation and flutter (AF). Methods A multivariate time-stratified case-crossover design was used to study the association. Cases were those patients aged 18 years or older living in the Reykjavik capital area during the study period, 2006–2017, who made emergency visits to Landspitali University Hospital for heart diseases. In this population-based study, the primary discharge diagnoses were registered according to International Classification of Diseases, 10th edition (ICD-10). The pollutants studied were NO 2 , PM 10 , PM 2.5 , and SO 2, with adjustment for H 2 S, temperature, and relative humidity. The 24-h mean of pollutants was used with lag 0 to lag 4. Results During the study period 9536 cases of AF were identified. The 24-h mean NO 2 was 20.7 μg/m 3 . Each 10 μg/m 3 increase in NO 2 was associated with increased risk of heart diseases (ICD-10: I20-I25, I44-I50), odds ratio (OR) 1.023 (95% CI 1.012–1.034) at lag 0. Each 10 μg/m 3 increase in NO 2 was associated with an increased risk of AF (ICD-10: I48) on the same day, OR 1.030 (95% CI: 1.011–1.049). Females were at higher risk for AF, OR 1.051 (95% CI 1.019–1.083) at lag 0, and OR 1.050 (95% CI 1.019–1.083) at lag 1. Females aged younger than 71 years had even higher risk for AF, OR 1.077 (95% CI: 1.025–1.131) at lag 0. Significant associations were found for other pollutants and emergency hospital visits, but they were weaker and did not show a discernable pattern. Conclusions Short-term increase in NO 2 concentrations was associated with heart diseases, more precisely with AF. The associations were stronger among females, and among females at younger age. This is the first study in Iceland that finds an association between air pollution and cardiac arrhythmias, so the results should be interpreted with caution. Article in Journal/Newspaper Iceland Springer Nature (via Crossref) Environmental Health 21 1 |
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Open Polar |
collection |
Springer Nature (via Crossref) |
op_collection_id |
crspringernat |
language |
English |
topic |
Health, Toxicology and Mutagenesis Public Health, Environmental and Occupational Health |
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Health, Toxicology and Mutagenesis Public Health, Environmental and Occupational Health Halldorsdottir, Solveig Finnbjornsdottir, Ragnhildur Gudrun Elvarsson, Bjarki Thor Gudmundsson, Gunnar Rafnsson, Vilhjalmur Ambient nitrogen dioxide is associated with emergency hospital visits for atrial fibrillation: a population-based case-crossover study in Reykjavik, Iceland |
topic_facet |
Health, Toxicology and Mutagenesis Public Health, Environmental and Occupational Health |
description |
Abstract Background In Iceland air quality is generally good; however, previous studies indicate that there is an association between air pollution in Reykjavik and adverse health effects as measured by dispensing of medications, mortality, and increase in health care utilisation. The aim was to study the association between traffic-related ambient air pollution in the Reykjavik capital area and emergency hospital visits for heart diseases and particularly atrial fibrillation and flutter (AF). Methods A multivariate time-stratified case-crossover design was used to study the association. Cases were those patients aged 18 years or older living in the Reykjavik capital area during the study period, 2006–2017, who made emergency visits to Landspitali University Hospital for heart diseases. In this population-based study, the primary discharge diagnoses were registered according to International Classification of Diseases, 10th edition (ICD-10). The pollutants studied were NO 2 , PM 10 , PM 2.5 , and SO 2, with adjustment for H 2 S, temperature, and relative humidity. The 24-h mean of pollutants was used with lag 0 to lag 4. Results During the study period 9536 cases of AF were identified. The 24-h mean NO 2 was 20.7 μg/m 3 . Each 10 μg/m 3 increase in NO 2 was associated with increased risk of heart diseases (ICD-10: I20-I25, I44-I50), odds ratio (OR) 1.023 (95% CI 1.012–1.034) at lag 0. Each 10 μg/m 3 increase in NO 2 was associated with an increased risk of AF (ICD-10: I48) on the same day, OR 1.030 (95% CI: 1.011–1.049). Females were at higher risk for AF, OR 1.051 (95% CI 1.019–1.083) at lag 0, and OR 1.050 (95% CI 1.019–1.083) at lag 1. Females aged younger than 71 years had even higher risk for AF, OR 1.077 (95% CI: 1.025–1.131) at lag 0. Significant associations were found for other pollutants and emergency hospital visits, but they were weaker and did not show a discernable pattern. Conclusions Short-term increase in NO 2 concentrations was associated with heart diseases, more precisely with AF. The associations were stronger among females, and among females at younger age. This is the first study in Iceland that finds an association between air pollution and cardiac arrhythmias, so the results should be interpreted with caution. |
format |
Article in Journal/Newspaper |
author |
Halldorsdottir, Solveig Finnbjornsdottir, Ragnhildur Gudrun Elvarsson, Bjarki Thor Gudmundsson, Gunnar Rafnsson, Vilhjalmur |
author_facet |
Halldorsdottir, Solveig Finnbjornsdottir, Ragnhildur Gudrun Elvarsson, Bjarki Thor Gudmundsson, Gunnar Rafnsson, Vilhjalmur |
author_sort |
Halldorsdottir, Solveig |
title |
Ambient nitrogen dioxide is associated with emergency hospital visits for atrial fibrillation: a population-based case-crossover study in Reykjavik, Iceland |
title_short |
Ambient nitrogen dioxide is associated with emergency hospital visits for atrial fibrillation: a population-based case-crossover study in Reykjavik, Iceland |
title_full |
Ambient nitrogen dioxide is associated with emergency hospital visits for atrial fibrillation: a population-based case-crossover study in Reykjavik, Iceland |
title_fullStr |
Ambient nitrogen dioxide is associated with emergency hospital visits for atrial fibrillation: a population-based case-crossover study in Reykjavik, Iceland |
title_full_unstemmed |
Ambient nitrogen dioxide is associated with emergency hospital visits for atrial fibrillation: a population-based case-crossover study in Reykjavik, Iceland |
title_sort |
ambient nitrogen dioxide is associated with emergency hospital visits for atrial fibrillation: a population-based case-crossover study in reykjavik, iceland |
publisher |
Springer Science and Business Media LLC |
publishDate |
2022 |
url |
http://dx.doi.org/10.1186/s12940-021-00817-9 https://link.springer.com/content/pdf/10.1186/s12940-021-00817-9.pdf https://link.springer.com/article/10.1186/s12940-021-00817-9/fulltext.html |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Environmental Health volume 21, issue 1 ISSN 1476-069X |
op_rights |
https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1186/s12940-021-00817-9 |
container_title |
Environmental Health |
container_volume |
21 |
container_issue |
1 |
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1766038574919057408 |