Multimorbidity and achievement of treatment goals among patients with type 2 diabetes: a primary care, real-world study

Abstract Background Type 2 diabetes (T2D), with its prevalence and disability-causing nature, is a challenge for primary health care. Most patients with T2D are multimorbid, i.e. have one or more long-term diseases in addition to T2D. Multimorbidity may play a role in the achievement of T2D treatmen...

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Published in:BMC Health Services Research
Main Authors: Heikkala, Eveliina, Mikkola, Ilona, Jokelainen, Jari, Timonen, Markku, Hagnäs, Maria
Format: Article in Journal/Newspaper
Language:English
Published: Springer Science and Business Media LLC 2021
Subjects:
Online Access:http://dx.doi.org/10.1186/s12913-021-06989-x
https://link.springer.com/content/pdf/10.1186/s12913-021-06989-x.pdf
https://link.springer.com/article/10.1186/s12913-021-06989-x/fulltext.html
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spelling crspringernat:10.1186/s12913-021-06989-x 2023-05-15T18:07:42+02:00 Multimorbidity and achievement of treatment goals among patients with type 2 diabetes: a primary care, real-world study Heikkala, Eveliina Mikkola, Ilona Jokelainen, Jari Timonen, Markku Hagnäs, Maria 2021 http://dx.doi.org/10.1186/s12913-021-06989-x https://link.springer.com/content/pdf/10.1186/s12913-021-06989-x.pdf https://link.springer.com/article/10.1186/s12913-021-06989-x/fulltext.html en eng Springer Science and Business Media LLC https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 CC-BY BMC Health Services Research volume 21, issue 1 ISSN 1472-6963 Health Policy journal-article 2021 crspringernat https://doi.org/10.1186/s12913-021-06989-x 2022-01-04T15:30:34Z Abstract Background Type 2 diabetes (T2D), with its prevalence and disability-causing nature, is a challenge for primary health care. Most patients with T2D are multimorbid, i.e. have one or more long-term diseases in addition to T2D. Multimorbidity may play a role in the achievement of T2D treatment targets, but is still not fully understood. The aims of the present cross-sectional, register-based study were to evaluate the prevalence and the most common patterns of multimorbidity among patients with T2D; and to study the potential associations between multimorbidity and treatment goal achievement, including measurements of glycosylated haemoglobin A1c (HbA1c), low-density lipoprotein (LDL) and systolic blood pressure (sBP). Methods The study population consisted of 4545 primary care patients who received a T2D diagnosis between January 2011 and July 2019 in Rovaniemi Health Centre, Finland. Data on seven long-term concordant (T2D-related) diseases, eight long-term discordant (non-T2D-related) diseases, potential confounders (age, sex, body mass index, prescribed medication), and the outcomes studied were collected from patients’ records. Logistic regression models with odds ratios (ORs) and 95 % confidence intervals (CIs) were assessed to determine the associations between multimorbidity and the achievement of treatment targets. Results Altogether, 93 % of the patients had one or more diseases in addition to T2D, i.e. were considered multimorbid. Furthermore, 21 % had only concordant disease(s) (Concordant subgroup), 8 % had only discordant disease(s) (Discordant subgroup) and 64 % had both (Concordant and discordant subgroup). As either single diseases or in combination with others, hypertension, musculoskeletal (MS) disease and hyperlipidaemia were the most prevalent multimorbidity patterns. Being multimorbid in general (OR 1.32, CI 1.01–1.70) and belonging to the Concordant (OR 1.45, CI 1.08–1.95) and Concordant and discordant (OR 1.31, CI 1.00–1.72) subgroups was associated with achievement of the HbA1c treatment target. Belonging to the Concordant and discordant subgroup was related to meeting the LDL treatment target (OR 1.31, CI 1.00–1.72). Conclusions Multimorbidity, including cardiovascular risk and the musculoskeletal disease burden, was extremely prevalent among the T2D patients who consulted primary health care. Primary care clinicians should survey the possible co-existence of long-term diseases among T2D patients to help maintain adequate treatment of T2D. Article in Journal/Newspaper Rovaniemi Springer Nature (via Crossref) Rovaniemi ENVELOPE(26.159,26.159,66.392,66.392) BMC Health Services Research 21 1
institution Open Polar
collection Springer Nature (via Crossref)
op_collection_id crspringernat
language English
topic Health Policy
spellingShingle Health Policy
Heikkala, Eveliina
Mikkola, Ilona
Jokelainen, Jari
Timonen, Markku
Hagnäs, Maria
Multimorbidity and achievement of treatment goals among patients with type 2 diabetes: a primary care, real-world study
topic_facet Health Policy
description Abstract Background Type 2 diabetes (T2D), with its prevalence and disability-causing nature, is a challenge for primary health care. Most patients with T2D are multimorbid, i.e. have one or more long-term diseases in addition to T2D. Multimorbidity may play a role in the achievement of T2D treatment targets, but is still not fully understood. The aims of the present cross-sectional, register-based study were to evaluate the prevalence and the most common patterns of multimorbidity among patients with T2D; and to study the potential associations between multimorbidity and treatment goal achievement, including measurements of glycosylated haemoglobin A1c (HbA1c), low-density lipoprotein (LDL) and systolic blood pressure (sBP). Methods The study population consisted of 4545 primary care patients who received a T2D diagnosis between January 2011 and July 2019 in Rovaniemi Health Centre, Finland. Data on seven long-term concordant (T2D-related) diseases, eight long-term discordant (non-T2D-related) diseases, potential confounders (age, sex, body mass index, prescribed medication), and the outcomes studied were collected from patients’ records. Logistic regression models with odds ratios (ORs) and 95 % confidence intervals (CIs) were assessed to determine the associations between multimorbidity and the achievement of treatment targets. Results Altogether, 93 % of the patients had one or more diseases in addition to T2D, i.e. were considered multimorbid. Furthermore, 21 % had only concordant disease(s) (Concordant subgroup), 8 % had only discordant disease(s) (Discordant subgroup) and 64 % had both (Concordant and discordant subgroup). As either single diseases or in combination with others, hypertension, musculoskeletal (MS) disease and hyperlipidaemia were the most prevalent multimorbidity patterns. Being multimorbid in general (OR 1.32, CI 1.01–1.70) and belonging to the Concordant (OR 1.45, CI 1.08–1.95) and Concordant and discordant (OR 1.31, CI 1.00–1.72) subgroups was associated with achievement of the HbA1c treatment target. Belonging to the Concordant and discordant subgroup was related to meeting the LDL treatment target (OR 1.31, CI 1.00–1.72). Conclusions Multimorbidity, including cardiovascular risk and the musculoskeletal disease burden, was extremely prevalent among the T2D patients who consulted primary health care. Primary care clinicians should survey the possible co-existence of long-term diseases among T2D patients to help maintain adequate treatment of T2D.
format Article in Journal/Newspaper
author Heikkala, Eveliina
Mikkola, Ilona
Jokelainen, Jari
Timonen, Markku
Hagnäs, Maria
author_facet Heikkala, Eveliina
Mikkola, Ilona
Jokelainen, Jari
Timonen, Markku
Hagnäs, Maria
author_sort Heikkala, Eveliina
title Multimorbidity and achievement of treatment goals among patients with type 2 diabetes: a primary care, real-world study
title_short Multimorbidity and achievement of treatment goals among patients with type 2 diabetes: a primary care, real-world study
title_full Multimorbidity and achievement of treatment goals among patients with type 2 diabetes: a primary care, real-world study
title_fullStr Multimorbidity and achievement of treatment goals among patients with type 2 diabetes: a primary care, real-world study
title_full_unstemmed Multimorbidity and achievement of treatment goals among patients with type 2 diabetes: a primary care, real-world study
title_sort multimorbidity and achievement of treatment goals among patients with type 2 diabetes: a primary care, real-world study
publisher Springer Science and Business Media LLC
publishDate 2021
url http://dx.doi.org/10.1186/s12913-021-06989-x
https://link.springer.com/content/pdf/10.1186/s12913-021-06989-x.pdf
https://link.springer.com/article/10.1186/s12913-021-06989-x/fulltext.html
long_lat ENVELOPE(26.159,26.159,66.392,66.392)
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