First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters
Abstract Background Variants of the Ostreid herpesvirus 1 (OsHV-1) cause high losses of Pacific oysters globally, including in Tomales Bay, California, USA. A suite of new variants, the OsHV-1 microvariants (μvars), cause very high mortalities of Pacific oysters in major oyster-growing regions outsi...
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Online Access: | http://dx.doi.org/10.1186/s12863-019-0791-3 http://link.springer.com/content/pdf/10.1186/s12863-019-0791-3.pdf http://link.springer.com/article/10.1186/s12863-019-0791-3/fulltext.html |
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crspringernat:10.1186/s12863-019-0791-3 2023-05-15T17:54:21+02:00 First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters Divilov, Konstantin Schoolfield, Blaine Morga, Benjamin Dégremont, Lionel Burge, Colleen A. Mancilla Cortez, Daniel Friedman, Carolyn S. Fleener, Gary B. Dumbauld, Brett R. Langdon, Chris Agricultural Research Service 2019 http://dx.doi.org/10.1186/s12863-019-0791-3 http://link.springer.com/content/pdf/10.1186/s12863-019-0791-3.pdf http://link.springer.com/article/10.1186/s12863-019-0791-3/fulltext.html en eng Springer Science and Business Media LLC http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/ CC-BY BMC Genetics volume 20, issue 1 ISSN 1471-2156 Genetics (clinical) Genetics journal-article 2019 crspringernat https://doi.org/10.1186/s12863-019-0791-3 2022-01-04T08:33:34Z Abstract Background Variants of the Ostreid herpesvirus 1 (OsHV-1) cause high losses of Pacific oysters globally, including in Tomales Bay, California, USA. A suite of new variants, the OsHV-1 microvariants (μvars), cause very high mortalities of Pacific oysters in major oyster-growing regions outside of the United States. There are currently no known Pacific oysters in the United States that are resistant to OsHV-1 as resistance has yet to be evaluated in these oysters. As part of an effort to begin genetic selection for resistance to OsHV-1, 71 families from the Molluscan Broodstock Program, a US West Coast Pacific oyster breeding program, were screened for survival after exposure to OsHV-1 in Tomales Bay. They were also tested in a quarantine laboratory in France where they were exposed to a French OsHV-1 microvariant using a plate assay, with survival recorded from three to seven days post-infection. Results Significant heritability for survival were found for all time points in the plate assay and in the survival phenotype from a single mortality count in Tomales Bay. Genetic correlations between survival against the French OsHV-1 μvar in the plate assay and the Tomales Bay variant in the field trait were weak or non-significant. Conclusions Future breeding efforts will seek to validate the potential of genetic improvement for survival to OsHV-1 through selection using the Molluscan Broodstock Program oysters. The lack of a strong correlation in survival between OsHV-1 variants under this study’s exposure conditions may require independent selection pressure for survival to each variant in order to make simultaneous genetic gains in resistance. Article in Journal/Newspaper Pacific oyster Springer Nature (via Crossref) Pacific BMC Genetics 20 1 |
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Springer Nature (via Crossref) |
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crspringernat |
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English |
topic |
Genetics (clinical) Genetics |
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Genetics (clinical) Genetics Divilov, Konstantin Schoolfield, Blaine Morga, Benjamin Dégremont, Lionel Burge, Colleen A. Mancilla Cortez, Daniel Friedman, Carolyn S. Fleener, Gary B. Dumbauld, Brett R. Langdon, Chris First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
topic_facet |
Genetics (clinical) Genetics |
description |
Abstract Background Variants of the Ostreid herpesvirus 1 (OsHV-1) cause high losses of Pacific oysters globally, including in Tomales Bay, California, USA. A suite of new variants, the OsHV-1 microvariants (μvars), cause very high mortalities of Pacific oysters in major oyster-growing regions outside of the United States. There are currently no known Pacific oysters in the United States that are resistant to OsHV-1 as resistance has yet to be evaluated in these oysters. As part of an effort to begin genetic selection for resistance to OsHV-1, 71 families from the Molluscan Broodstock Program, a US West Coast Pacific oyster breeding program, were screened for survival after exposure to OsHV-1 in Tomales Bay. They were also tested in a quarantine laboratory in France where they were exposed to a French OsHV-1 microvariant using a plate assay, with survival recorded from three to seven days post-infection. Results Significant heritability for survival were found for all time points in the plate assay and in the survival phenotype from a single mortality count in Tomales Bay. Genetic correlations between survival against the French OsHV-1 μvar in the plate assay and the Tomales Bay variant in the field trait were weak or non-significant. Conclusions Future breeding efforts will seek to validate the potential of genetic improvement for survival to OsHV-1 through selection using the Molluscan Broodstock Program oysters. The lack of a strong correlation in survival between OsHV-1 variants under this study’s exposure conditions may require independent selection pressure for survival to each variant in order to make simultaneous genetic gains in resistance. |
author2 |
Agricultural Research Service |
format |
Article in Journal/Newspaper |
author |
Divilov, Konstantin Schoolfield, Blaine Morga, Benjamin Dégremont, Lionel Burge, Colleen A. Mancilla Cortez, Daniel Friedman, Carolyn S. Fleener, Gary B. Dumbauld, Brett R. Langdon, Chris |
author_facet |
Divilov, Konstantin Schoolfield, Blaine Morga, Benjamin Dégremont, Lionel Burge, Colleen A. Mancilla Cortez, Daniel Friedman, Carolyn S. Fleener, Gary B. Dumbauld, Brett R. Langdon, Chris |
author_sort |
Divilov, Konstantin |
title |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_short |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_full |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_fullStr |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_full_unstemmed |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_sort |
first evaluation of resistance to both a california oshv-1 variant and a french oshv-1 microvariant in pacific oysters |
publisher |
Springer Science and Business Media LLC |
publishDate |
2019 |
url |
http://dx.doi.org/10.1186/s12863-019-0791-3 http://link.springer.com/content/pdf/10.1186/s12863-019-0791-3.pdf http://link.springer.com/article/10.1186/s12863-019-0791-3/fulltext.html |
geographic |
Pacific |
geographic_facet |
Pacific |
genre |
Pacific oyster |
genre_facet |
Pacific oyster |
op_source |
BMC Genetics volume 20, issue 1 ISSN 1471-2156 |
op_rights |
http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/ |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1186/s12863-019-0791-3 |
container_title |
BMC Genetics |
container_volume |
20 |
container_issue |
1 |
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1766162099301515264 |