Association of air pollution and use of glyceryl trinitrate against angina pectoris: a population-based case-crossover study
Abstract Background Ambient air pollution has been associated with increased cardiovascular morbidity and mortality. In Reykjavik, Iceland, air pollutant concentrations exceed official health limits several times every year. The aim was to study the association of concentrations of NO 2 , O 3 , PM 1...
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Format: | Article in Journal/Newspaper |
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Springer Science and Business Media LLC
2013
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Online Access: | http://dx.doi.org/10.1186/1476-069x-12-38 http://link.springer.com/content/pdf/10.1186/1476-069X-12-38.pdf http://link.springer.com/article/10.1186/1476-069X-12-38/fulltext.html http://link.springer.com/content/pdf/10.1186/1476-069X-12-38 https://link.springer.com/content/pdf/10.1186/1476-069X-12-38.pdf |
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crspringernat:10.1186/1476-069x-12-38 2023-05-15T16:48:34+02:00 Association of air pollution and use of glyceryl trinitrate against angina pectoris: a population-based case-crossover study Finnbjornsdottir, Ragnhildur Gudrun Zoëga, Helga Olafsson, Orn Thorsteinsson, Throstur Rafnsson, Vilhjalmur 2013 http://dx.doi.org/10.1186/1476-069x-12-38 http://link.springer.com/content/pdf/10.1186/1476-069X-12-38.pdf http://link.springer.com/article/10.1186/1476-069X-12-38/fulltext.html http://link.springer.com/content/pdf/10.1186/1476-069X-12-38 https://link.springer.com/content/pdf/10.1186/1476-069X-12-38.pdf en eng Springer Science and Business Media LLC http://www.springer.com/tdm Environmental Health volume 12, issue 1 ISSN 1476-069X Health, Toxicology and Mutagenesis Public Health, Environmental and Occupational Health journal-article 2013 crspringernat https://doi.org/10.1186/1476-069x-12-38 2022-01-04T09:05:31Z Abstract Background Ambient air pollution has been associated with increased cardiovascular morbidity and mortality. In Reykjavik, Iceland, air pollutant concentrations exceed official health limits several times every year. The aim was to study the association of concentrations of NO 2 , O 3 , PM 10 , and H 2 S in the Reykjavik capital area with the dispensing of anti-angina pectoris medication, glyceryl trinitrate to the inhabitants. Methods Data on daily dispensing of glyceryl trinitrate , were retrieved from the Icelandic Medicines Registry. Data on hourly concentrations of NO 2 , O 3 , PM 10 , and H 2 S were obtained from the Environment Agency of Iceland. A case-crossover design was used, based on the dispensing of glyceryl trinitrate to 5,246 individuals (≥18 years) between 2005 and 2009. Results For every 10 μg/m 3 increase of NO 2 and O 3 3-day mean concentrations, the odds ratio (OR) for daily dispensing of glyceryl trinitrates was 1.136 (95% confidence intervals (CI) 1.069-1.207) and 1.094 (95% CI 1.029-1.163) at lag 0, and OR was 1.096 (95% CI 1.029-1.168) and 1.094 (95% CI 1.028-1.166) at lag 1, respectively. Conclusions These findings suggest that NO 2 and O 3 ambient air concentrations may adversely affect cardiovascular health, as measured by the dispensing of glyceryl trinitrates for angina pectoris. Further, the findings suggest that data on the dispensing of medication may be a valuable health indicator when studying the effect of air pollution on cardiovascular morbidity. Article in Journal/Newspaper Iceland Springer Nature (via Crossref) Environmental Health 12 1 |
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Open Polar |
collection |
Springer Nature (via Crossref) |
op_collection_id |
crspringernat |
language |
English |
topic |
Health, Toxicology and Mutagenesis Public Health, Environmental and Occupational Health |
spellingShingle |
Health, Toxicology and Mutagenesis Public Health, Environmental and Occupational Health Finnbjornsdottir, Ragnhildur Gudrun Zoëga, Helga Olafsson, Orn Thorsteinsson, Throstur Rafnsson, Vilhjalmur Association of air pollution and use of glyceryl trinitrate against angina pectoris: a population-based case-crossover study |
topic_facet |
Health, Toxicology and Mutagenesis Public Health, Environmental and Occupational Health |
description |
Abstract Background Ambient air pollution has been associated with increased cardiovascular morbidity and mortality. In Reykjavik, Iceland, air pollutant concentrations exceed official health limits several times every year. The aim was to study the association of concentrations of NO 2 , O 3 , PM 10 , and H 2 S in the Reykjavik capital area with the dispensing of anti-angina pectoris medication, glyceryl trinitrate to the inhabitants. Methods Data on daily dispensing of glyceryl trinitrate , were retrieved from the Icelandic Medicines Registry. Data on hourly concentrations of NO 2 , O 3 , PM 10 , and H 2 S were obtained from the Environment Agency of Iceland. A case-crossover design was used, based on the dispensing of glyceryl trinitrate to 5,246 individuals (≥18 years) between 2005 and 2009. Results For every 10 μg/m 3 increase of NO 2 and O 3 3-day mean concentrations, the odds ratio (OR) for daily dispensing of glyceryl trinitrates was 1.136 (95% confidence intervals (CI) 1.069-1.207) and 1.094 (95% CI 1.029-1.163) at lag 0, and OR was 1.096 (95% CI 1.029-1.168) and 1.094 (95% CI 1.028-1.166) at lag 1, respectively. Conclusions These findings suggest that NO 2 and O 3 ambient air concentrations may adversely affect cardiovascular health, as measured by the dispensing of glyceryl trinitrates for angina pectoris. Further, the findings suggest that data on the dispensing of medication may be a valuable health indicator when studying the effect of air pollution on cardiovascular morbidity. |
format |
Article in Journal/Newspaper |
author |
Finnbjornsdottir, Ragnhildur Gudrun Zoëga, Helga Olafsson, Orn Thorsteinsson, Throstur Rafnsson, Vilhjalmur |
author_facet |
Finnbjornsdottir, Ragnhildur Gudrun Zoëga, Helga Olafsson, Orn Thorsteinsson, Throstur Rafnsson, Vilhjalmur |
author_sort |
Finnbjornsdottir, Ragnhildur Gudrun |
title |
Association of air pollution and use of glyceryl trinitrate against angina pectoris: a population-based case-crossover study |
title_short |
Association of air pollution and use of glyceryl trinitrate against angina pectoris: a population-based case-crossover study |
title_full |
Association of air pollution and use of glyceryl trinitrate against angina pectoris: a population-based case-crossover study |
title_fullStr |
Association of air pollution and use of glyceryl trinitrate against angina pectoris: a population-based case-crossover study |
title_full_unstemmed |
Association of air pollution and use of glyceryl trinitrate against angina pectoris: a population-based case-crossover study |
title_sort |
association of air pollution and use of glyceryl trinitrate against angina pectoris: a population-based case-crossover study |
publisher |
Springer Science and Business Media LLC |
publishDate |
2013 |
url |
http://dx.doi.org/10.1186/1476-069x-12-38 http://link.springer.com/content/pdf/10.1186/1476-069X-12-38.pdf http://link.springer.com/article/10.1186/1476-069X-12-38/fulltext.html http://link.springer.com/content/pdf/10.1186/1476-069X-12-38 https://link.springer.com/content/pdf/10.1186/1476-069X-12-38.pdf |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Environmental Health volume 12, issue 1 ISSN 1476-069X |
op_rights |
http://www.springer.com/tdm |
op_doi |
https://doi.org/10.1186/1476-069x-12-38 |
container_title |
Environmental Health |
container_volume |
12 |
container_issue |
1 |
_version_ |
1766038653387145216 |