High gene expression of inflammatory markers and IL-17A correlates with severity of injection site reactions of Atlantic salmon vaccinated with oil-adjuvanted vaccines

• Published in: BMC Genomics
• Main Authors: Mutoloki, Stephen, Cooper, Glenn A, Marjara, Inderjit S, Koop, Ben F, Evensen, Øystein
• Format: Article in Journal/Newspaper
• Language: English
• Published: Springer Science and Business Media LLC 2010
• Subjects: Genetics; Biotechnology; Gata; Atlantic salmon
• Online Access: http://dx.doi.org/10.1186/1471-2164-11-336; https://link.springer.com/content/pdf/10.1186/1471-2164-11-336.pdf

Abstract Background Two decades after the introduction of oil-based vaccines in the control of bacterial and viral diseases in farmed salmonids, the mechanisms of induced side effects manifested as intra-abdominal granulomas remain unresolved. Side effects have been associated with generation of aut...