Pathological pigmentation in cardiac tissues of Atlantic salmon (Salmo salar L.) with cardiomyopathy syndrome
Abstract It is widely accepted that melanin formation may play an immunologic role in invertebrates and ectothermic vertebrates. In farmed Atlantic salmon, cardiomyopathy syndrome (CMS) is a common viral disease associated with severe cardiac inflammation that may be accompanied by heavy melanisatio...
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2013
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Online Access: | http://dx.doi.org/10.1186/1297-9716-44-107 https://link.springer.com/content/pdf/10.1186/1297-9716-44-107.pdf |
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crspringernat:10.1186/1297-9716-44-107 2023-05-15T15:30:21+02:00 Pathological pigmentation in cardiac tissues of Atlantic salmon (Salmo salar L.) with cardiomyopathy syndrome Fagerland, Hilde AS Austbø, Lars Fritsvold, Camilla Alarcon, Marta Rimstad, Espen Falk, Knut Taksdal, Torunn Koppang, Erling O 2013 http://dx.doi.org/10.1186/1297-9716-44-107 https://link.springer.com/content/pdf/10.1186/1297-9716-44-107.pdf en eng Springer Science and Business Media LLC Veterinary Research volume 44, issue 1 ISSN 1297-9716 General Veterinary journal-article 2013 crspringernat https://doi.org/10.1186/1297-9716-44-107 2022-01-04T08:05:18Z Abstract It is widely accepted that melanin formation may play an immunologic role in invertebrates and ectothermic vertebrates. In farmed Atlantic salmon, cardiomyopathy syndrome (CMS) is a common viral disease associated with severe cardiac inflammation that may be accompanied by heavy melanisation of the heart. By the use of histology, laser capture microdissection and transcription analysis of tyrosinase genes, we here show that this melanisation is linked to de novo melanogenesis by melanomacrophages, suggesting an active part in the inflammatory reaction. No general systemic activation of the extracutaneous pigmentary system in response to viral infections with affinity to the heart was observed. Article in Journal/Newspaper Atlantic salmon Salmo salar Springer Nature (via Crossref) Veterinary Research 44 1 107 |
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Open Polar |
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Springer Nature (via Crossref) |
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language |
English |
topic |
General Veterinary |
spellingShingle |
General Veterinary Fagerland, Hilde AS Austbø, Lars Fritsvold, Camilla Alarcon, Marta Rimstad, Espen Falk, Knut Taksdal, Torunn Koppang, Erling O Pathological pigmentation in cardiac tissues of Atlantic salmon (Salmo salar L.) with cardiomyopathy syndrome |
topic_facet |
General Veterinary |
description |
Abstract It is widely accepted that melanin formation may play an immunologic role in invertebrates and ectothermic vertebrates. In farmed Atlantic salmon, cardiomyopathy syndrome (CMS) is a common viral disease associated with severe cardiac inflammation that may be accompanied by heavy melanisation of the heart. By the use of histology, laser capture microdissection and transcription analysis of tyrosinase genes, we here show that this melanisation is linked to de novo melanogenesis by melanomacrophages, suggesting an active part in the inflammatory reaction. No general systemic activation of the extracutaneous pigmentary system in response to viral infections with affinity to the heart was observed. |
format |
Article in Journal/Newspaper |
author |
Fagerland, Hilde AS Austbø, Lars Fritsvold, Camilla Alarcon, Marta Rimstad, Espen Falk, Knut Taksdal, Torunn Koppang, Erling O |
author_facet |
Fagerland, Hilde AS Austbø, Lars Fritsvold, Camilla Alarcon, Marta Rimstad, Espen Falk, Knut Taksdal, Torunn Koppang, Erling O |
author_sort |
Fagerland, Hilde AS |
title |
Pathological pigmentation in cardiac tissues of Atlantic salmon (Salmo salar L.) with cardiomyopathy syndrome |
title_short |
Pathological pigmentation in cardiac tissues of Atlantic salmon (Salmo salar L.) with cardiomyopathy syndrome |
title_full |
Pathological pigmentation in cardiac tissues of Atlantic salmon (Salmo salar L.) with cardiomyopathy syndrome |
title_fullStr |
Pathological pigmentation in cardiac tissues of Atlantic salmon (Salmo salar L.) with cardiomyopathy syndrome |
title_full_unstemmed |
Pathological pigmentation in cardiac tissues of Atlantic salmon (Salmo salar L.) with cardiomyopathy syndrome |
title_sort |
pathological pigmentation in cardiac tissues of atlantic salmon (salmo salar l.) with cardiomyopathy syndrome |
publisher |
Springer Science and Business Media LLC |
publishDate |
2013 |
url |
http://dx.doi.org/10.1186/1297-9716-44-107 https://link.springer.com/content/pdf/10.1186/1297-9716-44-107.pdf |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
Veterinary Research volume 44, issue 1 ISSN 1297-9716 |
op_doi |
https://doi.org/10.1186/1297-9716-44-107 |
container_title |
Veterinary Research |
container_volume |
44 |
container_issue |
1 |
container_start_page |
107 |
_version_ |
1766360792698978304 |