Identification and genome analysis of a novel picornavirus from captive belugas (Delphinapterus leucas) in China
Abstract The discovery of new viruses is important for predicting their potential threats to the health of humans and other animals. A novel picornavirus was identified from oral, throat, and anal swab samples collected from belugas ( Delphinapterus leucas ), from Dalian Sun Asia Tourism Holding Co....
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2021
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Online Access: | http://dx.doi.org/10.1038/s41598-021-00605-y https://www.nature.com/articles/s41598-021-00605-y.pdf https://www.nature.com/articles/s41598-021-00605-y |
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crspringernat:10.1038/s41598-021-00605-y 2023-05-15T15:42:00+02:00 Identification and genome analysis of a novel picornavirus from captive belugas (Delphinapterus leucas) in China Wang, Gaoyu Huang, Yi Zhang, Weijia Peng, Ruoyan Luo, Jun Liu, Sisi Bai, Shijie Hu, Xiaoyuan Wu, Zhiqiang Yang, Fan Shen, Shu Zhang, Yun Tang, Chuanning Cui, Xiuji Niu, Lina Lu, Gang Li, Songhai Deng, Fei Zhang, Peijun Du, Jiang Yin, Feifei Hainan Provincial Natural Science Foundation of China Key Research and Development Plan of Hainan Province Hainan talent development project Youth Innovation Promotion Association of Chinese Academy of Sciences National Natural Science Foundation of China Scientific and Technological Program of Strategic Priority in Chinese Academy of Sciences Scientific Research Foundation of the Higher Education Institutions of Hainan Province Scientific Research Foundation of the Higher Education Institutions of Hainan Province Research project of Hainan academician innovation platform Major Science and Technology Program of Hainan Province 2021 http://dx.doi.org/10.1038/s41598-021-00605-y https://www.nature.com/articles/s41598-021-00605-y.pdf https://www.nature.com/articles/s41598-021-00605-y en eng Springer Science and Business Media LLC https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 CC-BY Scientific Reports volume 11, issue 1 ISSN 2045-2322 Multidisciplinary journal-article 2021 crspringernat https://doi.org/10.1038/s41598-021-00605-y 2022-01-04T11:57:53Z Abstract The discovery of new viruses is important for predicting their potential threats to the health of humans and other animals. A novel picornavirus was identified from oral, throat, and anal swab samples collected from belugas ( Delphinapterus leucas ), from Dalian Sun Asia Tourism Holding Co., China, between January and December 2018, using a metagenomics approach. The genome of this novel PicoV-HMU-1 strain was 8197 nucleotides (nt) in length, with a open reading frame (from 1091 to 8074 nt) that encoded a polyprotein precursor of 2328 amino acids. Moreover, the genomic length and GC content of PicoV-HMU-1 were within the ranges found in other picornaviruses, and the genome organization was also similar. Nevertheless, PicoV-HMU-1 had a lower amino acid identity and distinct host species compared with other members of the Picornaviridae family. Phylogenetic trees were constructed based on the P1 and 3D amino acid sequences of PicoV-HMU-1 along with representative members of the Picornaviridae family, which showed that PicoV-HMU-1 was related to unclassified bat picornaviruses groups. These findings suggest that the PicoV-HMU-1 strain represents a potentially novel genus of picornavirus. These data can enhance our understanding of the picornavirus genetic diversity and evolution. Article in Journal/Newspaper Beluga* Delphinapterus leucas Springer Nature (via Crossref) Scientific Reports 11 1 |
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Springer Nature (via Crossref) |
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crspringernat |
language |
English |
topic |
Multidisciplinary |
spellingShingle |
Multidisciplinary Wang, Gaoyu Huang, Yi Zhang, Weijia Peng, Ruoyan Luo, Jun Liu, Sisi Bai, Shijie Hu, Xiaoyuan Wu, Zhiqiang Yang, Fan Shen, Shu Zhang, Yun Tang, Chuanning Cui, Xiuji Niu, Lina Lu, Gang Li, Songhai Deng, Fei Zhang, Peijun Du, Jiang Yin, Feifei Identification and genome analysis of a novel picornavirus from captive belugas (Delphinapterus leucas) in China |
topic_facet |
Multidisciplinary |
description |
Abstract The discovery of new viruses is important for predicting their potential threats to the health of humans and other animals. A novel picornavirus was identified from oral, throat, and anal swab samples collected from belugas ( Delphinapterus leucas ), from Dalian Sun Asia Tourism Holding Co., China, between January and December 2018, using a metagenomics approach. The genome of this novel PicoV-HMU-1 strain was 8197 nucleotides (nt) in length, with a open reading frame (from 1091 to 8074 nt) that encoded a polyprotein precursor of 2328 amino acids. Moreover, the genomic length and GC content of PicoV-HMU-1 were within the ranges found in other picornaviruses, and the genome organization was also similar. Nevertheless, PicoV-HMU-1 had a lower amino acid identity and distinct host species compared with other members of the Picornaviridae family. Phylogenetic trees were constructed based on the P1 and 3D amino acid sequences of PicoV-HMU-1 along with representative members of the Picornaviridae family, which showed that PicoV-HMU-1 was related to unclassified bat picornaviruses groups. These findings suggest that the PicoV-HMU-1 strain represents a potentially novel genus of picornavirus. These data can enhance our understanding of the picornavirus genetic diversity and evolution. |
author2 |
Hainan Provincial Natural Science Foundation of China Key Research and Development Plan of Hainan Province Hainan talent development project Youth Innovation Promotion Association of Chinese Academy of Sciences National Natural Science Foundation of China Scientific and Technological Program of Strategic Priority in Chinese Academy of Sciences Scientific Research Foundation of the Higher Education Institutions of Hainan Province Scientific Research Foundation of the Higher Education Institutions of Hainan Province Research project of Hainan academician innovation platform Major Science and Technology Program of Hainan Province |
format |
Article in Journal/Newspaper |
author |
Wang, Gaoyu Huang, Yi Zhang, Weijia Peng, Ruoyan Luo, Jun Liu, Sisi Bai, Shijie Hu, Xiaoyuan Wu, Zhiqiang Yang, Fan Shen, Shu Zhang, Yun Tang, Chuanning Cui, Xiuji Niu, Lina Lu, Gang Li, Songhai Deng, Fei Zhang, Peijun Du, Jiang Yin, Feifei |
author_facet |
Wang, Gaoyu Huang, Yi Zhang, Weijia Peng, Ruoyan Luo, Jun Liu, Sisi Bai, Shijie Hu, Xiaoyuan Wu, Zhiqiang Yang, Fan Shen, Shu Zhang, Yun Tang, Chuanning Cui, Xiuji Niu, Lina Lu, Gang Li, Songhai Deng, Fei Zhang, Peijun Du, Jiang Yin, Feifei |
author_sort |
Wang, Gaoyu |
title |
Identification and genome analysis of a novel picornavirus from captive belugas (Delphinapterus leucas) in China |
title_short |
Identification and genome analysis of a novel picornavirus from captive belugas (Delphinapterus leucas) in China |
title_full |
Identification and genome analysis of a novel picornavirus from captive belugas (Delphinapterus leucas) in China |
title_fullStr |
Identification and genome analysis of a novel picornavirus from captive belugas (Delphinapterus leucas) in China |
title_full_unstemmed |
Identification and genome analysis of a novel picornavirus from captive belugas (Delphinapterus leucas) in China |
title_sort |
identification and genome analysis of a novel picornavirus from captive belugas (delphinapterus leucas) in china |
publisher |
Springer Science and Business Media LLC |
publishDate |
2021 |
url |
http://dx.doi.org/10.1038/s41598-021-00605-y https://www.nature.com/articles/s41598-021-00605-y.pdf https://www.nature.com/articles/s41598-021-00605-y |
genre |
Beluga* Delphinapterus leucas |
genre_facet |
Beluga* Delphinapterus leucas |
op_source |
Scientific Reports volume 11, issue 1 ISSN 2045-2322 |
op_rights |
https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1038/s41598-021-00605-y |
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Scientific Reports |
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11 |
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