Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal
Abstract Biological invasions are major anthropogenic changes associated with threats to biodiversity and health. However, what determines the successful establishment and spread of introduced populations remains unclear. Here, we explore several hypotheses linking invasion success and immune phenot...
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Online Access: | http://dx.doi.org/10.1038/s41598-020-75060-2 https://www.nature.com/articles/s41598-020-75060-2.pdf https://www.nature.com/articles/s41598-020-75060-2 |
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crspringernat:10.1038/s41598-020-75060-2 2023-05-15T18:05:26+02:00 Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal Charbonnel, Nathalie Galan, Maxime Tatard, Caroline Loiseau, Anne Diagne, Christophe Dalecky, Ambroise Parrinello, Hugues Rialle, Stephanie Severac, Dany Brouat, Carine ANR: agence nationale de la recherche French Embassy in Senegal 2020 http://dx.doi.org/10.1038/s41598-020-75060-2 https://www.nature.com/articles/s41598-020-75060-2.pdf https://www.nature.com/articles/s41598-020-75060-2 en eng Springer Science and Business Media LLC https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 CC-BY Scientific Reports volume 10, issue 1 ISSN 2045-2322 Multidisciplinary journal-article 2020 crspringernat https://doi.org/10.1038/s41598-020-75060-2 2022-01-04T14:18:57Z Abstract Biological invasions are major anthropogenic changes associated with threats to biodiversity and health. However, what determines the successful establishment and spread of introduced populations remains unclear. Here, we explore several hypotheses linking invasion success and immune phenotype traits, including those based on the evolution of increased competitive ability concept. We compared gene expression profiles between anciently and recently established populations of two major invading species, the house mouse Mus musculus domesticus and the black rat Rattus rattus , in Senegal (West Africa). Transcriptome analyses identified differential expression between anciently and recently established populations for 364 mouse genes and 83 rat genes. All immune-related genes displaying differential expression along the mouse invasion route were overexpressed at three of the four recently invaded sites studied. Complement activation pathway genes were overrepresented among these genes. By contrast, no particular immunological process was found to be overrepresented among the differentially expressed genes of black rat. Changes in transcriptome profiles were thus observed along invasion routes, but with different specific patterns between the two invasive species. These changes may be driven by increases in infection risks at sites recently invaded by the house mouse, and by stochastic events associated with colonization history for the black rat. These results constitute a first step toward the identification of immune eco-evolutionary processes potentially involved in the invasion success of these two rodent species. Article in Journal/Newspaper Rattus rattus Springer Nature (via Crossref) Scientific Reports 10 1 |
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Springer Nature (via Crossref) |
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English |
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Multidisciplinary Charbonnel, Nathalie Galan, Maxime Tatard, Caroline Loiseau, Anne Diagne, Christophe Dalecky, Ambroise Parrinello, Hugues Rialle, Stephanie Severac, Dany Brouat, Carine Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal |
topic_facet |
Multidisciplinary |
description |
Abstract Biological invasions are major anthropogenic changes associated with threats to biodiversity and health. However, what determines the successful establishment and spread of introduced populations remains unclear. Here, we explore several hypotheses linking invasion success and immune phenotype traits, including those based on the evolution of increased competitive ability concept. We compared gene expression profiles between anciently and recently established populations of two major invading species, the house mouse Mus musculus domesticus and the black rat Rattus rattus , in Senegal (West Africa). Transcriptome analyses identified differential expression between anciently and recently established populations for 364 mouse genes and 83 rat genes. All immune-related genes displaying differential expression along the mouse invasion route were overexpressed at three of the four recently invaded sites studied. Complement activation pathway genes were overrepresented among these genes. By contrast, no particular immunological process was found to be overrepresented among the differentially expressed genes of black rat. Changes in transcriptome profiles were thus observed along invasion routes, but with different specific patterns between the two invasive species. These changes may be driven by increases in infection risks at sites recently invaded by the house mouse, and by stochastic events associated with colonization history for the black rat. These results constitute a first step toward the identification of immune eco-evolutionary processes potentially involved in the invasion success of these two rodent species. |
author2 |
ANR: agence nationale de la recherche French Embassy in Senegal |
format |
Article in Journal/Newspaper |
author |
Charbonnel, Nathalie Galan, Maxime Tatard, Caroline Loiseau, Anne Diagne, Christophe Dalecky, Ambroise Parrinello, Hugues Rialle, Stephanie Severac, Dany Brouat, Carine |
author_facet |
Charbonnel, Nathalie Galan, Maxime Tatard, Caroline Loiseau, Anne Diagne, Christophe Dalecky, Ambroise Parrinello, Hugues Rialle, Stephanie Severac, Dany Brouat, Carine |
author_sort |
Charbonnel, Nathalie |
title |
Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal |
title_short |
Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal |
title_full |
Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal |
title_fullStr |
Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal |
title_full_unstemmed |
Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal |
title_sort |
differential immune gene expression associated with contemporary range expansion in two invasive rodents in senegal |
publisher |
Springer Science and Business Media LLC |
publishDate |
2020 |
url |
http://dx.doi.org/10.1038/s41598-020-75060-2 https://www.nature.com/articles/s41598-020-75060-2.pdf https://www.nature.com/articles/s41598-020-75060-2 |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_source |
Scientific Reports volume 10, issue 1 ISSN 2045-2322 |
op_rights |
https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1038/s41598-020-75060-2 |
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Scientific Reports |
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10 |
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1 |
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1766176908891914240 |