In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden
Abstract The purpose was to review the incidence of in situ carcinoma in Iceland after initiating population-based mammography screening in 1987 and to compare management of ductal carcinoma in situ (DCIS) between Iceland and the Uppsala–Örebro region (UÖR) in Central Sweden. The Icelandic Cancer Re...
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2020
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Online Access: | http://dx.doi.org/10.1038/s41598-020-74134-5 https://www.nature.com/articles/s41598-020-74134-5.pdf https://www.nature.com/articles/s41598-020-74134-5 |
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crspringernat:10.1038/s41598-020-74134-5 2023-05-15T16:42:21+02:00 In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden Agustsson, Arnar S. Birgisson, Helgi Agnarsson, Bjarni A. Jonsson, Thorvaldur Stefansdottir, Hrefna Wärnberg, Fredrik Lambe, Mats Tryggvadottir, Laufey Sverrisdottir, Asgerdur 2020 http://dx.doi.org/10.1038/s41598-020-74134-5 https://www.nature.com/articles/s41598-020-74134-5.pdf https://www.nature.com/articles/s41598-020-74134-5 en eng Springer Science and Business Media LLC https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 CC-BY Scientific Reports volume 10, issue 1 ISSN 2045-2322 Multidisciplinary journal-article 2020 crspringernat https://doi.org/10.1038/s41598-020-74134-5 2022-01-04T07:15:15Z Abstract The purpose was to review the incidence of in situ carcinoma in Iceland after initiating population-based mammography screening in 1987 and to compare management of ductal carcinoma in situ (DCIS) between Iceland and the Uppsala–Örebro region (UÖR) in Central Sweden. The Icelandic Cancer Registry provided data on in situ breast carcinomas for women between 1957 and 2017. Clinical data for women with DCIS between 2008 and 2014 was extracted from hospital records and compared to women diagnosed in UÖR. In Iceland, in situ carcinoma incidence increased from 7 to 30 per 100 000 women per year, following the introduction of organised mammography screening. The proportion of in situ carcinoma of all breast carcinomas increased from 4 to 12%. More than one third (35%) of women diagnosed with DCIS in Iceland were older than 70 years versus 18% in UÖR. In Iceland, 49% of all DCIS women underwent mastectomy compared to 40% in UÖR. The incidence of in situ carcinoma in Iceland increased four-fold after the uptake of population-based mammography screening causing considerable risk of overtreatment. Differences in treatment of DCIS were seen between Iceland and UÖR, revealing the importance of quality registration for monitoring patterns of management. Article in Journal/Newspaper Iceland Springer Nature (via Crossref) Scientific Reports 10 1 |
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Springer Nature (via Crossref) |
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English |
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Multidisciplinary |
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Multidisciplinary Agustsson, Arnar S. Birgisson, Helgi Agnarsson, Bjarni A. Jonsson, Thorvaldur Stefansdottir, Hrefna Wärnberg, Fredrik Lambe, Mats Tryggvadottir, Laufey Sverrisdottir, Asgerdur In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
topic_facet |
Multidisciplinary |
description |
Abstract The purpose was to review the incidence of in situ carcinoma in Iceland after initiating population-based mammography screening in 1987 and to compare management of ductal carcinoma in situ (DCIS) between Iceland and the Uppsala–Örebro region (UÖR) in Central Sweden. The Icelandic Cancer Registry provided data on in situ breast carcinomas for women between 1957 and 2017. Clinical data for women with DCIS between 2008 and 2014 was extracted from hospital records and compared to women diagnosed in UÖR. In Iceland, in situ carcinoma incidence increased from 7 to 30 per 100 000 women per year, following the introduction of organised mammography screening. The proportion of in situ carcinoma of all breast carcinomas increased from 4 to 12%. More than one third (35%) of women diagnosed with DCIS in Iceland were older than 70 years versus 18% in UÖR. In Iceland, 49% of all DCIS women underwent mastectomy compared to 40% in UÖR. The incidence of in situ carcinoma in Iceland increased four-fold after the uptake of population-based mammography screening causing considerable risk of overtreatment. Differences in treatment of DCIS were seen between Iceland and UÖR, revealing the importance of quality registration for monitoring patterns of management. |
format |
Article in Journal/Newspaper |
author |
Agustsson, Arnar S. Birgisson, Helgi Agnarsson, Bjarni A. Jonsson, Thorvaldur Stefansdottir, Hrefna Wärnberg, Fredrik Lambe, Mats Tryggvadottir, Laufey Sverrisdottir, Asgerdur |
author_facet |
Agustsson, Arnar S. Birgisson, Helgi Agnarsson, Bjarni A. Jonsson, Thorvaldur Stefansdottir, Hrefna Wärnberg, Fredrik Lambe, Mats Tryggvadottir, Laufey Sverrisdottir, Asgerdur |
author_sort |
Agustsson, Arnar S. |
title |
In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
title_short |
In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
title_full |
In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
title_fullStr |
In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
title_full_unstemmed |
In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
title_sort |
in situ breast cancer incidence patterns in iceland and differences in ductal carcinoma in situ treatment compared to sweden |
publisher |
Springer Science and Business Media LLC |
publishDate |
2020 |
url |
http://dx.doi.org/10.1038/s41598-020-74134-5 https://www.nature.com/articles/s41598-020-74134-5.pdf https://www.nature.com/articles/s41598-020-74134-5 |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Scientific Reports volume 10, issue 1 ISSN 2045-2322 |
op_rights |
https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1038/s41598-020-74134-5 |
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Scientific Reports |
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10 |
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