Longitudinal Analysis of Paraspinal Muscle Cross-Sectional Area During Early Adulthood – A 10-Year Follow-Up MRI Study
Abstract Only a few previous studies have investigated paraspinal musculature (i.e., multifidus (MF), psoas major (PSM), erector spinae (ES)) in longitudinal, population-based settings. This study aimed to evaluate changes in the cross-sectional area (CSA) of the paraspinal muscles between the ages...
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crspringernat:10.1038/s41598-019-56186-4 2023-05-15T17:42:40+02:00 Longitudinal Analysis of Paraspinal Muscle Cross-Sectional Area During Early Adulthood – A 10-Year Follow-Up MRI Study Mäki, Teemu Oura, Petteri Paananen, Markus Niinimäki, Jaakko Karppinen, Jaro Junno, Juho-Antti 2019 http://dx.doi.org/10.1038/s41598-019-56186-4 http://www.nature.com/articles/s41598-019-56186-4.pdf http://www.nature.com/articles/s41598-019-56186-4 en eng Springer Science and Business Media LLC https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 CC-BY Scientific Reports volume 9, issue 1 ISSN 2045-2322 Multidisciplinary journal-article 2019 crspringernat https://doi.org/10.1038/s41598-019-56186-4 2022-01-04T12:00:32Z Abstract Only a few previous studies have investigated paraspinal musculature (i.e., multifidus (MF), psoas major (PSM), erector spinae (ES)) in longitudinal, population-based settings. This study aimed to evaluate changes in the cross-sectional area (CSA) of the paraspinal muscles between the ages of 20 and 30 years. The study population consisted of a sub-cohort from the Northern Finland Birth Cohort 1986 (n = 298; 156 men, 142 women). Baseline magnetic resonance imaging was performed at a mean age of 21.3 years and follow-up imaging at 30.6 years. The CSA measurements were performed by tracing the paraspinal muscle outlines individually (MF, ES, PM) and all combined (total muscle area (TMA)) at the L4 cranial endplate level. The longitudinal data analysis was performed using generalized estimating equations modelling. The CSA of MF and ES increased during the follow-up among both sexes (men: MF + 5.7%, p < 0.001; ES + 2.7%, p = 0.001; and women: MF + 10.5%, p < 0.001; ES 9.2%, p = 0.001). The CSA of PM decreased among men (PM −4.0%, p < 0.001) but not among women (PM + 0.5%, p = 0.553). TMA increased significantly only among women (men: +0.5%, p = 0.425; women: +6.5%, p < 0.001). The increases in ES and TMA were more distinct among women than men (p < 0.001). Our study demonstrated clear age- and sex-related changes in paraspinal muscle size in early adulthood. Article in Journal/Newspaper Northern Finland Springer Nature (via Crossref) Scientific Reports 9 1 |
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Multidisciplinary Mäki, Teemu Oura, Petteri Paananen, Markus Niinimäki, Jaakko Karppinen, Jaro Junno, Juho-Antti Longitudinal Analysis of Paraspinal Muscle Cross-Sectional Area During Early Adulthood – A 10-Year Follow-Up MRI Study |
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Multidisciplinary |
description |
Abstract Only a few previous studies have investigated paraspinal musculature (i.e., multifidus (MF), psoas major (PSM), erector spinae (ES)) in longitudinal, population-based settings. This study aimed to evaluate changes in the cross-sectional area (CSA) of the paraspinal muscles between the ages of 20 and 30 years. The study population consisted of a sub-cohort from the Northern Finland Birth Cohort 1986 (n = 298; 156 men, 142 women). Baseline magnetic resonance imaging was performed at a mean age of 21.3 years and follow-up imaging at 30.6 years. The CSA measurements were performed by tracing the paraspinal muscle outlines individually (MF, ES, PM) and all combined (total muscle area (TMA)) at the L4 cranial endplate level. The longitudinal data analysis was performed using generalized estimating equations modelling. The CSA of MF and ES increased during the follow-up among both sexes (men: MF + 5.7%, p < 0.001; ES + 2.7%, p = 0.001; and women: MF + 10.5%, p < 0.001; ES 9.2%, p = 0.001). The CSA of PM decreased among men (PM −4.0%, p < 0.001) but not among women (PM + 0.5%, p = 0.553). TMA increased significantly only among women (men: +0.5%, p = 0.425; women: +6.5%, p < 0.001). The increases in ES and TMA were more distinct among women than men (p < 0.001). Our study demonstrated clear age- and sex-related changes in paraspinal muscle size in early adulthood. |
format |
Article in Journal/Newspaper |
author |
Mäki, Teemu Oura, Petteri Paananen, Markus Niinimäki, Jaakko Karppinen, Jaro Junno, Juho-Antti |
author_facet |
Mäki, Teemu Oura, Petteri Paananen, Markus Niinimäki, Jaakko Karppinen, Jaro Junno, Juho-Antti |
author_sort |
Mäki, Teemu |
title |
Longitudinal Analysis of Paraspinal Muscle Cross-Sectional Area During Early Adulthood – A 10-Year Follow-Up MRI Study |
title_short |
Longitudinal Analysis of Paraspinal Muscle Cross-Sectional Area During Early Adulthood – A 10-Year Follow-Up MRI Study |
title_full |
Longitudinal Analysis of Paraspinal Muscle Cross-Sectional Area During Early Adulthood – A 10-Year Follow-Up MRI Study |
title_fullStr |
Longitudinal Analysis of Paraspinal Muscle Cross-Sectional Area During Early Adulthood – A 10-Year Follow-Up MRI Study |
title_full_unstemmed |
Longitudinal Analysis of Paraspinal Muscle Cross-Sectional Area During Early Adulthood – A 10-Year Follow-Up MRI Study |
title_sort |
longitudinal analysis of paraspinal muscle cross-sectional area during early adulthood – a 10-year follow-up mri study |
publisher |
Springer Science and Business Media LLC |
publishDate |
2019 |
url |
http://dx.doi.org/10.1038/s41598-019-56186-4 http://www.nature.com/articles/s41598-019-56186-4.pdf http://www.nature.com/articles/s41598-019-56186-4 |
genre |
Northern Finland |
genre_facet |
Northern Finland |
op_source |
Scientific Reports volume 9, issue 1 ISSN 2045-2322 |
op_rights |
https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1038/s41598-019-56186-4 |
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Scientific Reports |
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9 |
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