How patients being treated for non-small cell lung cancer value treatment benefit despite side effects
Abstract Purpose To describe symptoms and side effects experienced by patients with advanced non-small cell lung cancer (NSCLC), assess how patients allocate sensations (i.e. symptoms or side effects) to either the disease or its treatment, and evaluate how patients balance side effects with treatme...
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2021
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Online Access: | http://dx.doi.org/10.1007/s11136-021-02882-6 https://link.springer.com/content/pdf/10.1007/s11136-021-02882-6.pdf https://link.springer.com/article/10.1007/s11136-021-02882-6/fulltext.html |
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crspringernat:10.1007/s11136-021-02882-6 2023-05-15T15:00:04+02:00 How patients being treated for non-small cell lung cancer value treatment benefit despite side effects Martin, Mona L. Correll, Julia Walding, Andrew Rydén, Anna AstraZeneca 2021 http://dx.doi.org/10.1007/s11136-021-02882-6 https://link.springer.com/content/pdf/10.1007/s11136-021-02882-6.pdf https://link.springer.com/article/10.1007/s11136-021-02882-6/fulltext.html en eng Springer Science and Business Media LLC https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 CC-BY Quality of Life Research ISSN 0962-9343 1573-2649 Public Health, Environmental and Occupational Health journal-article 2021 crspringernat https://doi.org/10.1007/s11136-021-02882-6 2022-01-04T16:49:11Z Abstract Purpose To describe symptoms and side effects experienced by patients with advanced non-small cell lung cancer (NSCLC), assess how patients allocate sensations (i.e. symptoms or side effects) to either the disease or its treatment, and evaluate how patients balance side effects with treatment benefits. Methods Qualitative sub-studies were conducted as part of two clinical trials in patients treated for advanced NSCLC (AURA [NCT01802632]; ARCTIC [NCT02352948]). Results Interviews were conducted with 23 patients and 19 patients in the AURA and ARCTIC sub-studies, respectively. The most commonly experienced symptoms/side effects were respiratory (81% of patients), digestive (76%), pain and discomfort (76%), energy-related (71%), and sensory (62%). Patients identified a sensation as a treatment side effect if they had not experienced it before, if there was a temporal link between the sensation and receipt of treatment, and/or if their doctors consistently told or asked them about it in relation to side effects. Themes that emerged when patients talked about their cancer treatment and its side effects related to the serious nature of their advanced disease and their treatment expectations. Patients focused on treatment benefits, wanting a better quality of life, being hopeful, not really having a choice, and not thinking about side effects. Conclusions In these two qualitative sub-studies, patients with advanced NSCLC valued the benefits of their treatment regardless of side effects that they experienced. Patients weighed their options against the seriousness of their disease and expressed their willingness to tolerate their side effects in return for receiving continued treatment benefits. Article in Journal/Newspaper Arctic Springer Nature (via Crossref) Arctic Quality of Life Research |
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Springer Nature (via Crossref) |
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English |
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Public Health, Environmental and Occupational Health |
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Public Health, Environmental and Occupational Health Martin, Mona L. Correll, Julia Walding, Andrew Rydén, Anna How patients being treated for non-small cell lung cancer value treatment benefit despite side effects |
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Public Health, Environmental and Occupational Health |
description |
Abstract Purpose To describe symptoms and side effects experienced by patients with advanced non-small cell lung cancer (NSCLC), assess how patients allocate sensations (i.e. symptoms or side effects) to either the disease or its treatment, and evaluate how patients balance side effects with treatment benefits. Methods Qualitative sub-studies were conducted as part of two clinical trials in patients treated for advanced NSCLC (AURA [NCT01802632]; ARCTIC [NCT02352948]). Results Interviews were conducted with 23 patients and 19 patients in the AURA and ARCTIC sub-studies, respectively. The most commonly experienced symptoms/side effects were respiratory (81% of patients), digestive (76%), pain and discomfort (76%), energy-related (71%), and sensory (62%). Patients identified a sensation as a treatment side effect if they had not experienced it before, if there was a temporal link between the sensation and receipt of treatment, and/or if their doctors consistently told or asked them about it in relation to side effects. Themes that emerged when patients talked about their cancer treatment and its side effects related to the serious nature of their advanced disease and their treatment expectations. Patients focused on treatment benefits, wanting a better quality of life, being hopeful, not really having a choice, and not thinking about side effects. Conclusions In these two qualitative sub-studies, patients with advanced NSCLC valued the benefits of their treatment regardless of side effects that they experienced. Patients weighed their options against the seriousness of their disease and expressed their willingness to tolerate their side effects in return for receiving continued treatment benefits. |
author2 |
AstraZeneca |
format |
Article in Journal/Newspaper |
author |
Martin, Mona L. Correll, Julia Walding, Andrew Rydén, Anna |
author_facet |
Martin, Mona L. Correll, Julia Walding, Andrew Rydén, Anna |
author_sort |
Martin, Mona L. |
title |
How patients being treated for non-small cell lung cancer value treatment benefit despite side effects |
title_short |
How patients being treated for non-small cell lung cancer value treatment benefit despite side effects |
title_full |
How patients being treated for non-small cell lung cancer value treatment benefit despite side effects |
title_fullStr |
How patients being treated for non-small cell lung cancer value treatment benefit despite side effects |
title_full_unstemmed |
How patients being treated for non-small cell lung cancer value treatment benefit despite side effects |
title_sort |
how patients being treated for non-small cell lung cancer value treatment benefit despite side effects |
publisher |
Springer Science and Business Media LLC |
publishDate |
2021 |
url |
http://dx.doi.org/10.1007/s11136-021-02882-6 https://link.springer.com/content/pdf/10.1007/s11136-021-02882-6.pdf https://link.springer.com/article/10.1007/s11136-021-02882-6/fulltext.html |
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Arctic |
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Arctic |
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Arctic |
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Arctic |
op_source |
Quality of Life Research ISSN 0962-9343 1573-2649 |
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https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 |
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CC-BY |
op_doi |
https://doi.org/10.1007/s11136-021-02882-6 |
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Quality of Life Research |
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