The hemoglobin Gly16β1Asp polymorphism in turbot (Scophthalmus maximus) is differentially distributed across European populations
Abstract Turbot is an important flatfish widely distributed along the European coasts, whose fishery is centered in the North Sea. The commercial value of the species has boosted a successful aquaculture sector in Europe and China. Body growth is the main target of turbot breeding programs and is al...
Published in: | Fish Physiology and Biochemistry |
---|---|
Main Authors: | , , , |
Other Authors: | , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Springer Science and Business Media LLC
2020
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1007/s10695-020-00872-y https://link.springer.com/content/pdf/10.1007/s10695-020-00872-y.pdf https://link.springer.com/article/10.1007/s10695-020-00872-y/fulltext.html |
id |
crspringernat:10.1007/s10695-020-00872-y |
---|---|
record_format |
openpolar |
spelling |
crspringernat:10.1007/s10695-020-00872-y 2023-05-15T18:15:51+02:00 The hemoglobin Gly16β1Asp polymorphism in turbot (Scophthalmus maximus) is differentially distributed across European populations Andersen, Øivind Rubiolo, Juan Andrés De Rosa, Maria Cristina Martinez, Paulino EU AQUATRACE EU FISHBOOST 2020 http://dx.doi.org/10.1007/s10695-020-00872-y https://link.springer.com/content/pdf/10.1007/s10695-020-00872-y.pdf https://link.springer.com/article/10.1007/s10695-020-00872-y/fulltext.html en eng Springer Science and Business Media LLC https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 CC-BY Fish Physiology and Biochemistry volume 46, issue 6, page 2367-2376 ISSN 0920-1742 1573-5168 Aquatic Science General Medicine Physiology Biochemistry journal-article 2020 crspringernat https://doi.org/10.1007/s10695-020-00872-y 2022-01-04T16:14:57Z Abstract Turbot is an important flatfish widely distributed along the European coasts, whose fishery is centered in the North Sea. The commercial value of the species has boosted a successful aquaculture sector in Europe and China. Body growth is the main target of turbot breeding programs and is also a key trait related to local adaptation to temperature and salinity. Differences in growth rate and optimal growth temperature in turbot have been shown to be associated with a hemoglobin polymorphism reported more than 50 years ago. Here, we identified a Gly16Asp amino acid substitution in the β1 globin subunit by searching for genetic variation in the five functional globin genes within the whole annotated turbot genome. We predicted increased stability of the turbot hemoglobin by the replacement of the conserved Gly with the negative charged Asp residue that is consistent with the higher rate of αβ dimer assembly in the human J-Baltimore Gly16β->Asp mutant than in normal HbA. The turbot Hbβ1-Gly16 variant dominated in the northern populations examined, particularly in the Baltic Sea, while the Asp allele showed elevated frequencies in southern populations and was the prevalent variant in the Adriatic Sea. Body weight did not associate with the Hbβ1 genotypes at farming conditions (i.e., high oxygen levels, feeding ad libitum) after analyzing 90 fish with high growth dispersal from nine turbot families. Nevertheless, all data at hand suggest that the turbot hemoglobin polymorphism has an adaptive significance in the variable wild conditions regarding temperature and oxygen availability. Article in Journal/Newspaper Scophthalmus maximus Turbot Springer Nature (via Crossref) Fish Physiology and Biochemistry 46 6 2367 2376 |
institution |
Open Polar |
collection |
Springer Nature (via Crossref) |
op_collection_id |
crspringernat |
language |
English |
topic |
Aquatic Science General Medicine Physiology Biochemistry |
spellingShingle |
Aquatic Science General Medicine Physiology Biochemistry Andersen, Øivind Rubiolo, Juan Andrés De Rosa, Maria Cristina Martinez, Paulino The hemoglobin Gly16β1Asp polymorphism in turbot (Scophthalmus maximus) is differentially distributed across European populations |
topic_facet |
Aquatic Science General Medicine Physiology Biochemistry |
description |
Abstract Turbot is an important flatfish widely distributed along the European coasts, whose fishery is centered in the North Sea. The commercial value of the species has boosted a successful aquaculture sector in Europe and China. Body growth is the main target of turbot breeding programs and is also a key trait related to local adaptation to temperature and salinity. Differences in growth rate and optimal growth temperature in turbot have been shown to be associated with a hemoglobin polymorphism reported more than 50 years ago. Here, we identified a Gly16Asp amino acid substitution in the β1 globin subunit by searching for genetic variation in the five functional globin genes within the whole annotated turbot genome. We predicted increased stability of the turbot hemoglobin by the replacement of the conserved Gly with the negative charged Asp residue that is consistent with the higher rate of αβ dimer assembly in the human J-Baltimore Gly16β->Asp mutant than in normal HbA. The turbot Hbβ1-Gly16 variant dominated in the northern populations examined, particularly in the Baltic Sea, while the Asp allele showed elevated frequencies in southern populations and was the prevalent variant in the Adriatic Sea. Body weight did not associate with the Hbβ1 genotypes at farming conditions (i.e., high oxygen levels, feeding ad libitum) after analyzing 90 fish with high growth dispersal from nine turbot families. Nevertheless, all data at hand suggest that the turbot hemoglobin polymorphism has an adaptive significance in the variable wild conditions regarding temperature and oxygen availability. |
author2 |
EU AQUATRACE EU FISHBOOST |
format |
Article in Journal/Newspaper |
author |
Andersen, Øivind Rubiolo, Juan Andrés De Rosa, Maria Cristina Martinez, Paulino |
author_facet |
Andersen, Øivind Rubiolo, Juan Andrés De Rosa, Maria Cristina Martinez, Paulino |
author_sort |
Andersen, Øivind |
title |
The hemoglobin Gly16β1Asp polymorphism in turbot (Scophthalmus maximus) is differentially distributed across European populations |
title_short |
The hemoglobin Gly16β1Asp polymorphism in turbot (Scophthalmus maximus) is differentially distributed across European populations |
title_full |
The hemoglobin Gly16β1Asp polymorphism in turbot (Scophthalmus maximus) is differentially distributed across European populations |
title_fullStr |
The hemoglobin Gly16β1Asp polymorphism in turbot (Scophthalmus maximus) is differentially distributed across European populations |
title_full_unstemmed |
The hemoglobin Gly16β1Asp polymorphism in turbot (Scophthalmus maximus) is differentially distributed across European populations |
title_sort |
hemoglobin gly16β1asp polymorphism in turbot (scophthalmus maximus) is differentially distributed across european populations |
publisher |
Springer Science and Business Media LLC |
publishDate |
2020 |
url |
http://dx.doi.org/10.1007/s10695-020-00872-y https://link.springer.com/content/pdf/10.1007/s10695-020-00872-y.pdf https://link.springer.com/article/10.1007/s10695-020-00872-y/fulltext.html |
genre |
Scophthalmus maximus Turbot |
genre_facet |
Scophthalmus maximus Turbot |
op_source |
Fish Physiology and Biochemistry volume 46, issue 6, page 2367-2376 ISSN 0920-1742 1573-5168 |
op_rights |
https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1007/s10695-020-00872-y |
container_title |
Fish Physiology and Biochemistry |
container_volume |
46 |
container_issue |
6 |
container_start_page |
2367 |
op_container_end_page |
2376 |
_version_ |
1766189089672921088 |