Cardiovascular drug use among people with cognitive impairment living in nursing homes in northern Sweden
Abstract Purpose The aim of this study was to describe changes in the pattern of cardiovascular agents used in elderly people living in nursing homes between 2007 and 2013. Further, the aim was to analyse the use of cardiovascular drugs in relation to cognitive impairment and associated factors with...
Published in: | European Journal of Clinical Pharmacology |
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2020
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Online Access: | http://dx.doi.org/10.1007/s00228-019-02778-y http://link.springer.com/content/pdf/10.1007/s00228-019-02778-y.pdf http://link.springer.com/article/10.1007/s00228-019-02778-y/fulltext.html |
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crspringernat:10.1007/s00228-019-02778-y 2023-05-15T17:44:30+02:00 Cardiovascular drug use among people with cognitive impairment living in nursing homes in northern Sweden Svahn, Sofia Lövheim, Hugo Isaksson, Ulf Sandman, Per-Olof Gustafsson, Maria Demensförbundet Västerbotten County Council Hjärnfonden 2020 http://dx.doi.org/10.1007/s00228-019-02778-y http://link.springer.com/content/pdf/10.1007/s00228-019-02778-y.pdf http://link.springer.com/article/10.1007/s00228-019-02778-y/fulltext.html en eng Springer Science and Business Media LLC https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 CC-BY European Journal of Clinical Pharmacology volume 76, issue 4, page 525-537 ISSN 0031-6970 1432-1041 Pharmacology (medical) Pharmacology General Medicine journal-article 2020 crspringernat https://doi.org/10.1007/s00228-019-02778-y 2022-01-04T15:09:09Z Abstract Purpose The aim of this study was to describe changes in the pattern of cardiovascular agents used in elderly people living in nursing homes between 2007 and 2013. Further, the aim was to analyse the use of cardiovascular drugs in relation to cognitive impairment and associated factors within the same population, where prescription of loop diuretics was used as a proxy for heart failure. Methods Two questionnaire surveys were performed including 2494 people in 2007 and 1654 people in 2013 living in nursing homes in northern Sweden. Data were collected concerning drug use, functioning in activities of daily living (ADL) and cognition, using the Multi-Dimensional Dementia Assessment Scale (MDDAS). The use of different drugs and drug classes among people at four different levels of cognitive function in 2007 and 2013 were compared. Results The proportion of people prescribed ASA and diuretics was significantly lower at all four levels of cognitive function in 2013 compared to 2007. Among people prescribed loop diuretics, the use of angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers (ACEI/ARBs) increased from 37.8 to 45.6%, β-blockers from 36.0 to 41.8% and warfarin from 4.4 to 11.4%. The use of warfarin, ACEI/ARBs, β-blockers and mineralocorticoid receptor antagonists (MRAs) were less common among individuals with more severe cognitive impairment. Conclusion The results indicate that cardiovascular drug treatment has improved between 2007 and 2013, but there is room for further improvement, especially regarding adherence to guidelines for heart failure. Increasing cognitive impairment had an effect on treatment patterns for heart failure and atrial fibrillation. Article in Journal/Newspaper Northern Sweden Springer Nature (via Crossref) European Journal of Clinical Pharmacology 76 4 525 537 |
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Pharmacology (medical) Pharmacology General Medicine Svahn, Sofia Lövheim, Hugo Isaksson, Ulf Sandman, Per-Olof Gustafsson, Maria Cardiovascular drug use among people with cognitive impairment living in nursing homes in northern Sweden |
topic_facet |
Pharmacology (medical) Pharmacology General Medicine |
description |
Abstract Purpose The aim of this study was to describe changes in the pattern of cardiovascular agents used in elderly people living in nursing homes between 2007 and 2013. Further, the aim was to analyse the use of cardiovascular drugs in relation to cognitive impairment and associated factors within the same population, where prescription of loop diuretics was used as a proxy for heart failure. Methods Two questionnaire surveys were performed including 2494 people in 2007 and 1654 people in 2013 living in nursing homes in northern Sweden. Data were collected concerning drug use, functioning in activities of daily living (ADL) and cognition, using the Multi-Dimensional Dementia Assessment Scale (MDDAS). The use of different drugs and drug classes among people at four different levels of cognitive function in 2007 and 2013 were compared. Results The proportion of people prescribed ASA and diuretics was significantly lower at all four levels of cognitive function in 2013 compared to 2007. Among people prescribed loop diuretics, the use of angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers (ACEI/ARBs) increased from 37.8 to 45.6%, β-blockers from 36.0 to 41.8% and warfarin from 4.4 to 11.4%. The use of warfarin, ACEI/ARBs, β-blockers and mineralocorticoid receptor antagonists (MRAs) were less common among individuals with more severe cognitive impairment. Conclusion The results indicate that cardiovascular drug treatment has improved between 2007 and 2013, but there is room for further improvement, especially regarding adherence to guidelines for heart failure. Increasing cognitive impairment had an effect on treatment patterns for heart failure and atrial fibrillation. |
author2 |
Demensförbundet Västerbotten County Council Hjärnfonden |
format |
Article in Journal/Newspaper |
author |
Svahn, Sofia Lövheim, Hugo Isaksson, Ulf Sandman, Per-Olof Gustafsson, Maria |
author_facet |
Svahn, Sofia Lövheim, Hugo Isaksson, Ulf Sandman, Per-Olof Gustafsson, Maria |
author_sort |
Svahn, Sofia |
title |
Cardiovascular drug use among people with cognitive impairment living in nursing homes in northern Sweden |
title_short |
Cardiovascular drug use among people with cognitive impairment living in nursing homes in northern Sweden |
title_full |
Cardiovascular drug use among people with cognitive impairment living in nursing homes in northern Sweden |
title_fullStr |
Cardiovascular drug use among people with cognitive impairment living in nursing homes in northern Sweden |
title_full_unstemmed |
Cardiovascular drug use among people with cognitive impairment living in nursing homes in northern Sweden |
title_sort |
cardiovascular drug use among people with cognitive impairment living in nursing homes in northern sweden |
publisher |
Springer Science and Business Media LLC |
publishDate |
2020 |
url |
http://dx.doi.org/10.1007/s00228-019-02778-y http://link.springer.com/content/pdf/10.1007/s00228-019-02778-y.pdf http://link.springer.com/article/10.1007/s00228-019-02778-y/fulltext.html |
genre |
Northern Sweden |
genre_facet |
Northern Sweden |
op_source |
European Journal of Clinical Pharmacology volume 76, issue 4, page 525-537 ISSN 0031-6970 1432-1041 |
op_rights |
https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1007/s00228-019-02778-y |
container_title |
European Journal of Clinical Pharmacology |
container_volume |
76 |
container_issue |
4 |
container_start_page |
525 |
op_container_end_page |
537 |
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1766146729792503808 |