Temporal Trends in Incidence and Case Fatality of Intracerebral Hemorrhage: The Tromsø Study 1995-2012
Background: The aim of this study was to explore temporal trends in incidence and case fatality rates of intracerebral hemorrhage (ICH) over the last two decades in a Norwegian municipality. Methods: Incident cases of primary ICH were registered in the period from 1995 through 2012 in 32,530 partici...
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crskarger:10.1159/000447719 2024-06-09T07:49:58+00:00 Temporal Trends in Incidence and Case Fatality of Intracerebral Hemorrhage: The Tromsø Study 1995-2012 Carlsson, Maria Wilsgaard, Tom Johnsen, Stein Harald Vangen-Lønne, Anne Merete Løchen, Maja-Lisa Njølstad, Inger Mathiesen, Ellisiv Bøgeberg 2016 http://dx.doi.org/10.1159/000447719 https://www.karger.com/Article/Pdf/447719 en eng S. Karger AG https://creativecommons.org/licenses/by-nc-nd/4.0/ https://creativecommons.org/licenses/by-nc-nd/4.0/ Cerebrovascular Diseases Extra volume 6, issue 2, page 40-49 ISSN 1664-5456 journal-article 2016 crskarger https://doi.org/10.1159/000447719 2024-05-15T13:29:44Z Background: The aim of this study was to explore temporal trends in incidence and case fatality rates of intracerebral hemorrhage (ICH) over the last two decades in a Norwegian municipality. Methods: Incident cases of primary ICH were registered in the period from 1995 through 2012 in 32,530 participants of the longitudinal population-based Tromsø Study. Poisson regression models were used to obtain incidence rates over time in age- and sex-adjusted and age- and sex-specific models. Case fatality rates were calculated and age- and sex-adjusted trends over time were estimated using logistic regression. Results: A total of 226 ICHs were registered. The age- and sex-adjusted incidence rate [95% confidence interval (CI)] in the overall population was 0.42 (0.37-0.48) per 1,000 person-years. Age-adjusted incidence rates were 0.53 (0.43-0.62) in men and 0.33 (0.26-0.39) in women. In individuals aged <75 years, the age- and sex-adjusted incidence rate was 0.27 (0.22-0.32) and in individuals aged ≥75 years, it was 2.42 (1.95-2.89) per 1,000 person-years. There was no significant change in incidence rates over time. The incidence rate ratio (95% CI) in the overall population was 0.73 (0.47-1.12) in 2012 compared with 1995. The overall 30-day case fatality (95% CI) was 23.9% (18.3-29.5) and did not change substantially over time [odds ratio in 2012 vs. 1995 = 0.83 (95% CI 0.27-2.52)]. Conclusion: No significant changes in incidence and case fatality rates of ICH were observed during the last two decades. Article in Journal/Newspaper Tromsø Karger Tromsø Cerebrovascular Diseases Extra 6 2 40 49 |
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English |
description |
Background: The aim of this study was to explore temporal trends in incidence and case fatality rates of intracerebral hemorrhage (ICH) over the last two decades in a Norwegian municipality. Methods: Incident cases of primary ICH were registered in the period from 1995 through 2012 in 32,530 participants of the longitudinal population-based Tromsø Study. Poisson regression models were used to obtain incidence rates over time in age- and sex-adjusted and age- and sex-specific models. Case fatality rates were calculated and age- and sex-adjusted trends over time were estimated using logistic regression. Results: A total of 226 ICHs were registered. The age- and sex-adjusted incidence rate [95% confidence interval (CI)] in the overall population was 0.42 (0.37-0.48) per 1,000 person-years. Age-adjusted incidence rates were 0.53 (0.43-0.62) in men and 0.33 (0.26-0.39) in women. In individuals aged <75 years, the age- and sex-adjusted incidence rate was 0.27 (0.22-0.32) and in individuals aged ≥75 years, it was 2.42 (1.95-2.89) per 1,000 person-years. There was no significant change in incidence rates over time. The incidence rate ratio (95% CI) in the overall population was 0.73 (0.47-1.12) in 2012 compared with 1995. The overall 30-day case fatality (95% CI) was 23.9% (18.3-29.5) and did not change substantially over time [odds ratio in 2012 vs. 1995 = 0.83 (95% CI 0.27-2.52)]. Conclusion: No significant changes in incidence and case fatality rates of ICH were observed during the last two decades. |
format |
Article in Journal/Newspaper |
author |
Carlsson, Maria Wilsgaard, Tom Johnsen, Stein Harald Vangen-Lønne, Anne Merete Løchen, Maja-Lisa Njølstad, Inger Mathiesen, Ellisiv Bøgeberg |
spellingShingle |
Carlsson, Maria Wilsgaard, Tom Johnsen, Stein Harald Vangen-Lønne, Anne Merete Løchen, Maja-Lisa Njølstad, Inger Mathiesen, Ellisiv Bøgeberg Temporal Trends in Incidence and Case Fatality of Intracerebral Hemorrhage: The Tromsø Study 1995-2012 |
author_facet |
Carlsson, Maria Wilsgaard, Tom Johnsen, Stein Harald Vangen-Lønne, Anne Merete Løchen, Maja-Lisa Njølstad, Inger Mathiesen, Ellisiv Bøgeberg |
author_sort |
Carlsson, Maria |
title |
Temporal Trends in Incidence and Case Fatality of Intracerebral Hemorrhage: The Tromsø Study 1995-2012 |
title_short |
Temporal Trends in Incidence and Case Fatality of Intracerebral Hemorrhage: The Tromsø Study 1995-2012 |
title_full |
Temporal Trends in Incidence and Case Fatality of Intracerebral Hemorrhage: The Tromsø Study 1995-2012 |
title_fullStr |
Temporal Trends in Incidence and Case Fatality of Intracerebral Hemorrhage: The Tromsø Study 1995-2012 |
title_full_unstemmed |
Temporal Trends in Incidence and Case Fatality of Intracerebral Hemorrhage: The Tromsø Study 1995-2012 |
title_sort |
temporal trends in incidence and case fatality of intracerebral hemorrhage: the tromsø study 1995-2012 |
publisher |
S. Karger AG |
publishDate |
2016 |
url |
http://dx.doi.org/10.1159/000447719 https://www.karger.com/Article/Pdf/447719 |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_source |
Cerebrovascular Diseases Extra volume 6, issue 2, page 40-49 ISSN 1664-5456 |
op_rights |
https://creativecommons.org/licenses/by-nc-nd/4.0/ https://creativecommons.org/licenses/by-nc-nd/4.0/ |
op_doi |
https://doi.org/10.1159/000447719 |
container_title |
Cerebrovascular Diseases Extra |
container_volume |
6 |
container_issue |
2 |
container_start_page |
40 |
op_container_end_page |
49 |
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1801382926007402496 |