Vascular Access-Related Bloodstream Infections in First Nations, Community and Teaching Canadian Dialysis Units, and Other Centre-Level Predictors
Background/Aims: Vascular access-related bloodstream infection (BSI) is frequent among patients undergoing hemodialysis increasing their morbidity and mortality, but its occurrence across various dialysis centre types is not known. The aims of this study were to describe the incidence rates and asse...
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crskarger:10.1159/000262303 2024-06-09T07:46:01+00:00 Vascular Access-Related Bloodstream Infections in First Nations, Community and Teaching Canadian Dialysis Units, and Other Centre-Level Predictors Lafrance, Jean-Philippe Iqbal, Sameena Lelorier, Jacques Dasgupta, Kaberi Ritchie, Judith Ward, Linda Benaroya, Samuel Barré, Paul Cantarovich, Marcelo Ghannoum, Marc Proulx, Normand Vasilevsky, Murray Rahme, Elham 2009 http://dx.doi.org/10.1159/000262303 https://www.karger.com/Article/Pdf/262303 en eng S. Karger AG https://www.karger.com/Services/SiteLicenses https://www.karger.com/Services/SiteLicenses Nephron Clinical Practice volume 114, issue 3, page c204-c212 ISSN 1660-2110 journal-article 2009 crskarger https://doi.org/10.1159/000262303 2024-05-15T13:30:05Z Background/Aims: Vascular access-related bloodstream infection (BSI) is frequent among patients undergoing hemodialysis increasing their morbidity and mortality, but its occurrence across various dialysis centre types is not known. The aims of this study were to describe the incidence rates and assess the variability in BSI risk between dialysis centre types and other centre-level variables. Methods: We conducted a retrospective cohort study of 621 patients initiating hemodialysis in 7 Canadian dialysis centres. Cox regression models, where access type was continuously updated, were used to identify predictors of BSI occurrence. Results: During follow-up of the cohort (median age 68.1 years, 41.7% female, and 76.7% initiating with a central venous catheter, CVC), 73 patients had a BSI (rate: 0.21/1000 person-days). The BSI risk was not different in First Nation units (adjusted relative risk: 0.47, 95% confidence interval: 0.06–3.72) and teaching hospitals (1.33, 0.70–2.54) compared to community hospitals. No other centre-related variables were associated with the risk of BSI. Conclusion: We did not find differences in the BSI risk among dialysis unit types, or any other centre-related variables. The rates of BSI in our population were lower than those observed in other settings, but the high proportion of patients using CVCs is concerning. Article in Journal/Newspaper First Nations Karger Nephron Clinical Practice 114 3 c204 c212 |
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Background/Aims: Vascular access-related bloodstream infection (BSI) is frequent among patients undergoing hemodialysis increasing their morbidity and mortality, but its occurrence across various dialysis centre types is not known. The aims of this study were to describe the incidence rates and assess the variability in BSI risk between dialysis centre types and other centre-level variables. Methods: We conducted a retrospective cohort study of 621 patients initiating hemodialysis in 7 Canadian dialysis centres. Cox regression models, where access type was continuously updated, were used to identify predictors of BSI occurrence. Results: During follow-up of the cohort (median age 68.1 years, 41.7% female, and 76.7% initiating with a central venous catheter, CVC), 73 patients had a BSI (rate: 0.21/1000 person-days). The BSI risk was not different in First Nation units (adjusted relative risk: 0.47, 95% confidence interval: 0.06–3.72) and teaching hospitals (1.33, 0.70–2.54) compared to community hospitals. No other centre-related variables were associated with the risk of BSI. Conclusion: We did not find differences in the BSI risk among dialysis unit types, or any other centre-related variables. The rates of BSI in our population were lower than those observed in other settings, but the high proportion of patients using CVCs is concerning. |
format |
Article in Journal/Newspaper |
author |
Lafrance, Jean-Philippe Iqbal, Sameena Lelorier, Jacques Dasgupta, Kaberi Ritchie, Judith Ward, Linda Benaroya, Samuel Barré, Paul Cantarovich, Marcelo Ghannoum, Marc Proulx, Normand Vasilevsky, Murray Rahme, Elham |
spellingShingle |
Lafrance, Jean-Philippe Iqbal, Sameena Lelorier, Jacques Dasgupta, Kaberi Ritchie, Judith Ward, Linda Benaroya, Samuel Barré, Paul Cantarovich, Marcelo Ghannoum, Marc Proulx, Normand Vasilevsky, Murray Rahme, Elham Vascular Access-Related Bloodstream Infections in First Nations, Community and Teaching Canadian Dialysis Units, and Other Centre-Level Predictors |
author_facet |
Lafrance, Jean-Philippe Iqbal, Sameena Lelorier, Jacques Dasgupta, Kaberi Ritchie, Judith Ward, Linda Benaroya, Samuel Barré, Paul Cantarovich, Marcelo Ghannoum, Marc Proulx, Normand Vasilevsky, Murray Rahme, Elham |
author_sort |
Lafrance, Jean-Philippe |
title |
Vascular Access-Related Bloodstream Infections in First Nations, Community and Teaching Canadian Dialysis Units, and Other Centre-Level Predictors |
title_short |
Vascular Access-Related Bloodstream Infections in First Nations, Community and Teaching Canadian Dialysis Units, and Other Centre-Level Predictors |
title_full |
Vascular Access-Related Bloodstream Infections in First Nations, Community and Teaching Canadian Dialysis Units, and Other Centre-Level Predictors |
title_fullStr |
Vascular Access-Related Bloodstream Infections in First Nations, Community and Teaching Canadian Dialysis Units, and Other Centre-Level Predictors |
title_full_unstemmed |
Vascular Access-Related Bloodstream Infections in First Nations, Community and Teaching Canadian Dialysis Units, and Other Centre-Level Predictors |
title_sort |
vascular access-related bloodstream infections in first nations, community and teaching canadian dialysis units, and other centre-level predictors |
publisher |
S. Karger AG |
publishDate |
2009 |
url |
http://dx.doi.org/10.1159/000262303 https://www.karger.com/Article/Pdf/262303 |
genre |
First Nations |
genre_facet |
First Nations |
op_source |
Nephron Clinical Practice volume 114, issue 3, page c204-c212 ISSN 1660-2110 |
op_rights |
https://www.karger.com/Services/SiteLicenses https://www.karger.com/Services/SiteLicenses |
op_doi |
https://doi.org/10.1159/000262303 |
container_title |
Nephron Clinical Practice |
container_volume |
114 |
container_issue |
3 |
container_start_page |
c204 |
op_container_end_page |
c212 |
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1801375693038157824 |