Perinatal Vitamin A (Retinol) Status of Northern Canadian Mothers and Their Infants
Vitamin A (retinol) status was determined in two groups living in the northern part of Canada: native (Indian and Inuit) and non-native (Caucasian). The dietary intake of vitamin A and its plasma concentration were measured prenatally, at delivery and postnatally in mothers. Plasma concentrations we...
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1996
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Online Access: | http://dx.doi.org/10.1159/000244288 https://www.karger.com/Article/Pdf/244288 |
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crskarger:10.1159/000244288 2024-09-30T14:37:43+00:00 Perinatal Vitamin A (Retinol) Status of Northern Canadian Mothers and Their Infants Godel, John C. Basu, Tapan K. Pabst, Henry F. Hodges, Robert S. Hodges, Phyllis E. Ng, Margaret L. 1996 http://dx.doi.org/10.1159/000244288 https://www.karger.com/Article/Pdf/244288 en eng S. Karger AG https://www.karger.com/Services/SiteLicenses https://www.karger.com/Services/SiteLicenses Neonatology volume 69, issue 3, page 133-139 ISSN 1661-7800 1661-7819 journal-article 1996 crskarger https://doi.org/10.1159/000244288 2024-09-18T04:06:58Z Vitamin A (retinol) status was determined in two groups living in the northern part of Canada: native (Indian and Inuit) and non-native (Caucasian). The dietary intake of vitamin A and its plasma concentration were measured prenatally, at delivery and postnatally in mothers. Plasma concentrations were also measured at birth and postnatally in their infants. The mean vitamin A intake of native mothers was significantly lower than that of non-native mothers, 661 ± 485 versus 1,377 ± 1,418 retinol equivalents (p < 0.00005), with a higher risk of deficiency without supplementation, 35% versus 8%. Plasma retinol concentrations, although not in the deficient range, were significantly lower in native than non-native mothers prenatally and postnatally. Infant mean plasma retinol concentrations at birth averaged only 52% of those of their mothers and were significantly lower among native than non-native infants although no clinical evidence of vitamin A deficiency was noted. We speculate that vitamin A supplementation in native Northern Canadian mothers during pregnancy and in their neonates during infancy may have a role to play in the prevention of vitamin A deficiency. We also postulate that plasma retinol concentrations of 50-60% of maternal levels and between 0.7 and 2.5 µmol/l represent a ‘normal’ range for newborn infants. Article in Journal/Newspaper inuit Karger Canada Indian Neonatology 69 3 133 139 |
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English |
description |
Vitamin A (retinol) status was determined in two groups living in the northern part of Canada: native (Indian and Inuit) and non-native (Caucasian). The dietary intake of vitamin A and its plasma concentration were measured prenatally, at delivery and postnatally in mothers. Plasma concentrations were also measured at birth and postnatally in their infants. The mean vitamin A intake of native mothers was significantly lower than that of non-native mothers, 661 ± 485 versus 1,377 ± 1,418 retinol equivalents (p < 0.00005), with a higher risk of deficiency without supplementation, 35% versus 8%. Plasma retinol concentrations, although not in the deficient range, were significantly lower in native than non-native mothers prenatally and postnatally. Infant mean plasma retinol concentrations at birth averaged only 52% of those of their mothers and were significantly lower among native than non-native infants although no clinical evidence of vitamin A deficiency was noted. We speculate that vitamin A supplementation in native Northern Canadian mothers during pregnancy and in their neonates during infancy may have a role to play in the prevention of vitamin A deficiency. We also postulate that plasma retinol concentrations of 50-60% of maternal levels and between 0.7 and 2.5 µmol/l represent a ‘normal’ range for newborn infants. |
format |
Article in Journal/Newspaper |
author |
Godel, John C. Basu, Tapan K. Pabst, Henry F. Hodges, Robert S. Hodges, Phyllis E. Ng, Margaret L. |
spellingShingle |
Godel, John C. Basu, Tapan K. Pabst, Henry F. Hodges, Robert S. Hodges, Phyllis E. Ng, Margaret L. Perinatal Vitamin A (Retinol) Status of Northern Canadian Mothers and Their Infants |
author_facet |
Godel, John C. Basu, Tapan K. Pabst, Henry F. Hodges, Robert S. Hodges, Phyllis E. Ng, Margaret L. |
author_sort |
Godel, John C. |
title |
Perinatal Vitamin A (Retinol) Status of Northern Canadian Mothers and Their Infants |
title_short |
Perinatal Vitamin A (Retinol) Status of Northern Canadian Mothers and Their Infants |
title_full |
Perinatal Vitamin A (Retinol) Status of Northern Canadian Mothers and Their Infants |
title_fullStr |
Perinatal Vitamin A (Retinol) Status of Northern Canadian Mothers and Their Infants |
title_full_unstemmed |
Perinatal Vitamin A (Retinol) Status of Northern Canadian Mothers and Their Infants |
title_sort |
perinatal vitamin a (retinol) status of northern canadian mothers and their infants |
publisher |
S. Karger AG |
publishDate |
1996 |
url |
http://dx.doi.org/10.1159/000244288 https://www.karger.com/Article/Pdf/244288 |
geographic |
Canada Indian |
geographic_facet |
Canada Indian |
genre |
inuit |
genre_facet |
inuit |
op_source |
Neonatology volume 69, issue 3, page 133-139 ISSN 1661-7800 1661-7819 |
op_rights |
https://www.karger.com/Services/SiteLicenses https://www.karger.com/Services/SiteLicenses |
op_doi |
https://doi.org/10.1159/000244288 |
container_title |
Neonatology |
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69 |
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3 |
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133 |
op_container_end_page |
139 |
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1811640504855560192 |