The Reykjavik Eye Study – Prevalence of Lens Opacification with Reference to Identical Japanese Studies
Purpose: A population-based cataract epidemiological study, the Reykjavik Eye Study, was conducted to determine the prevalence and characteristics of lens opacities in Iceland. The results were compared with those from previous surveys in Japan to determine the influence of race and environmental fa...
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crskarger:10.1159/000027535 2024-06-16T07:40:54+00:00 The Reykjavik Eye Study – Prevalence of Lens Opacification with Reference to Identical Japanese Studies Sasaki, Hiroshi Jonasson, Fridbert Kojima, Masami Katoh, Nobuyo Ono, Masaji Takahashi, Nobuo Sasaki, Kazuyuki 2000 http://dx.doi.org/10.1159/000027535 https://www.karger.com/Article/Pdf/27535 en eng S. Karger AG https://www.karger.com/Services/SiteLicenses https://www.karger.com/Services/SiteLicenses Ophthalmologica volume 214, issue 6, page 412-420 ISSN 0030-3755 1423-0267 journal-article 2000 crskarger https://doi.org/10.1159/000027535 2024-05-22T12:59:36Z Purpose: A population-based cataract epidemiological study, the Reykjavik Eye Study, was conducted to determine the prevalence and characteristics of lens opacities in Iceland. The results were compared with those from previous surveys in Japan to determine the influence of race and environmental factors. Methods: 1,635 randomly selected residents of Reykjavik, Iceland, were enrolled, and among them, 1,045 responded and took part in the study. The subjects received ophthalmological examination of both the anterior and the posterior segments. Changes in the crystalline lens were examined and photographed under maximal pupillary dilation. Classification of the opacity types and grading of the extent of lens opacificiation were done using a standardized scheme, and the data were analyzed with Student’s test, the χ 2 test and the Mantel-Haenszel test. Results: The prevalence of lens opacities in subjects in their 50s, 60s, 70s and in those 80 years and older was 42.7, 61.0, 85.3 and 100%, respectively. Grade II and III lens opacities were found in 2.2% of subjects in their 50s and in 10.5, 35.9 and 62.3% in their 60s, 70s, and over 80 years, respectively. Cortical opacities predominated in all age groups followed by nuclear opacities; subcapsular opacities, on the other hand, were quite rare. A unique type of opacity, i.e., granular opacity, seldom seen among the Japanese, was found in 6.6% of the Icelandic subjects. Conclusions: Our results show that cortical opacity is the major type of opacity in Icelandic subjects, although its prevalence was lower than that in the Japanese subjects. Interestingly, the first appearance of lens opacities of grades II and III in Icelanders was delayed by 10 years compared to the Japanese suggesting fewer or less severe risk factors for cataract formation in Iceland. Article in Journal/Newspaper Iceland Karger Ophthalmologica 214 6 412 420 |
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English |
description |
Purpose: A population-based cataract epidemiological study, the Reykjavik Eye Study, was conducted to determine the prevalence and characteristics of lens opacities in Iceland. The results were compared with those from previous surveys in Japan to determine the influence of race and environmental factors. Methods: 1,635 randomly selected residents of Reykjavik, Iceland, were enrolled, and among them, 1,045 responded and took part in the study. The subjects received ophthalmological examination of both the anterior and the posterior segments. Changes in the crystalline lens were examined and photographed under maximal pupillary dilation. Classification of the opacity types and grading of the extent of lens opacificiation were done using a standardized scheme, and the data were analyzed with Student’s test, the χ 2 test and the Mantel-Haenszel test. Results: The prevalence of lens opacities in subjects in their 50s, 60s, 70s and in those 80 years and older was 42.7, 61.0, 85.3 and 100%, respectively. Grade II and III lens opacities were found in 2.2% of subjects in their 50s and in 10.5, 35.9 and 62.3% in their 60s, 70s, and over 80 years, respectively. Cortical opacities predominated in all age groups followed by nuclear opacities; subcapsular opacities, on the other hand, were quite rare. A unique type of opacity, i.e., granular opacity, seldom seen among the Japanese, was found in 6.6% of the Icelandic subjects. Conclusions: Our results show that cortical opacity is the major type of opacity in Icelandic subjects, although its prevalence was lower than that in the Japanese subjects. Interestingly, the first appearance of lens opacities of grades II and III in Icelanders was delayed by 10 years compared to the Japanese suggesting fewer or less severe risk factors for cataract formation in Iceland. |
format |
Article in Journal/Newspaper |
author |
Sasaki, Hiroshi Jonasson, Fridbert Kojima, Masami Katoh, Nobuyo Ono, Masaji Takahashi, Nobuo Sasaki, Kazuyuki |
spellingShingle |
Sasaki, Hiroshi Jonasson, Fridbert Kojima, Masami Katoh, Nobuyo Ono, Masaji Takahashi, Nobuo Sasaki, Kazuyuki The Reykjavik Eye Study – Prevalence of Lens Opacification with Reference to Identical Japanese Studies |
author_facet |
Sasaki, Hiroshi Jonasson, Fridbert Kojima, Masami Katoh, Nobuyo Ono, Masaji Takahashi, Nobuo Sasaki, Kazuyuki |
author_sort |
Sasaki, Hiroshi |
title |
The Reykjavik Eye Study – Prevalence of Lens Opacification with Reference to Identical Japanese Studies |
title_short |
The Reykjavik Eye Study – Prevalence of Lens Opacification with Reference to Identical Japanese Studies |
title_full |
The Reykjavik Eye Study – Prevalence of Lens Opacification with Reference to Identical Japanese Studies |
title_fullStr |
The Reykjavik Eye Study – Prevalence of Lens Opacification with Reference to Identical Japanese Studies |
title_full_unstemmed |
The Reykjavik Eye Study – Prevalence of Lens Opacification with Reference to Identical Japanese Studies |
title_sort |
reykjavik eye study – prevalence of lens opacification with reference to identical japanese studies |
publisher |
S. Karger AG |
publishDate |
2000 |
url |
http://dx.doi.org/10.1159/000027535 https://www.karger.com/Article/Pdf/27535 |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Ophthalmologica volume 214, issue 6, page 412-420 ISSN 0030-3755 1423-0267 |
op_rights |
https://www.karger.com/Services/SiteLicenses https://www.karger.com/Services/SiteLicenses |
op_doi |
https://doi.org/10.1159/000027535 |
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Ophthalmologica |
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214 |
container_issue |
6 |
container_start_page |
412 |
op_container_end_page |
420 |
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1802007943105740800 |