Enzymatic Hydrolysis of 4′-(1-Chloro-2-Acetoxyethyl)-Benzo-15-Crown-5-Ether and 4′-Acetoxyethyl-Benzo-15-Crown-5-Ether; a Facile Synthesis of the Optically Active Chlorohydrin Analogue Incorporating Crown Ether

Optically active chlorohydrin analog incorporating crown ether was synthesised by enzymatic hydrolysis using Candida Antarctica lipase in high enantiomeric excess.

Bibliographic Details
Published in:Journal of Chemical Research
Main Authors: Kijima, Tatsuro, Moriya, Takanori, Izumi, Taeko
Format: Article in Journal/Newspaper
Language:English
Published: SAGE Publications 2003
Subjects:
General Chemistry
Antarc*
Antarctica
Online Access:http://dx.doi.org/10.3184/030823403103174362
http://journals.sagepub.com/doi/pdf/10.3184/030823403103174362
Description
Summary:Optically active chlorohydrin analog incorporating crown ether was synthesised by enzymatic hydrolysis using Candida Antarctica lipase in high enantiomeric excess.

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