Autonomic nervous function in mice and voles ( Microtus arvalis): investigation by power spectral analysis of heart rate variability
We have studied the autonomic nervous function in voles ( Microtus arvalis) and mice. For this purpose, ECGs were recorded from conscious and unrestrained voles and mice using radiotelemetry and the autonomic nervous function was investigated by the power spectral analysis of heart rate variability....
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1996
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Online Access: | http://dx.doi.org/10.1258/002367796780739880 https://journals.sagepub.com/doi/pdf/10.1258/002367796780739880 |
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crsagepubl:10.1258/002367796780739880 2024-10-06T13:50:38+00:00 Autonomic nervous function in mice and voles ( Microtus arvalis): investigation by power spectral analysis of heart rate variability Ishii, K. Kuwahara, M. Tsubone, H. Sugano, S. 1996 http://dx.doi.org/10.1258/002367796780739880 https://journals.sagepub.com/doi/pdf/10.1258/002367796780739880 en eng SAGE Publications https://journals.sagepub.com/page/policies/text-and-data-mining-license Laboratory Animals volume 30, issue 4, page 359-364 ISSN 0023-6772 1758-1117 journal-article 1996 crsagepubl https://doi.org/10.1258/002367796780739880 2024-09-10T04:25:21Z We have studied the autonomic nervous function in voles ( Microtus arvalis) and mice. For this purpose, ECGs were recorded from conscious and unrestrained voles and mice using radiotelemetry and the autonomic nervous function was investigated by the power spectral analysis of heart rate variability. Heart rate in voles was lower than mice and the coefficient of variance was larger in voles. In the power spectra of voles and mice, there were two major spectral components with the high frequency (HF) peak generally appearing between 2.0 and 4.0 Hz, and the low frequency (LF) peak appearing below 0.6 Hz. On the basis of this data, we set the two frequency bands as LF (0.1-1.0 Hz) and HF (1.0-5.0 Hz) to evaluate autonomic nervous function. The LF and HF powers were larger in voles than mice. The LF/HF ratio was thought to provide a convenient index of autonomic nervous balance and was smaller in voles than mice. The LF powers in both species were reduced by atropine, but propranolol reduced the LF power only in mice. The HF power was reduced by atropine only in voles. The intrinsic heart rate produced by a double blockade with atropine and propranolol in voles was almost the same as control levels, but in mice was lower than controls. The ratio of the LF and HF powers by a double blockade were almost the same as those of the administration of atropine in voles, but nearer to propranolol in mice. These results suggested that the parasympathetic nervous function was predominant in voles, but the sympathetic one was predominant in mice. Article in Journal/Newspaper Microtus arvalis SAGE Publications Laboratory Animals 30 4 359 364 |
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description |
We have studied the autonomic nervous function in voles ( Microtus arvalis) and mice. For this purpose, ECGs were recorded from conscious and unrestrained voles and mice using radiotelemetry and the autonomic nervous function was investigated by the power spectral analysis of heart rate variability. Heart rate in voles was lower than mice and the coefficient of variance was larger in voles. In the power spectra of voles and mice, there were two major spectral components with the high frequency (HF) peak generally appearing between 2.0 and 4.0 Hz, and the low frequency (LF) peak appearing below 0.6 Hz. On the basis of this data, we set the two frequency bands as LF (0.1-1.0 Hz) and HF (1.0-5.0 Hz) to evaluate autonomic nervous function. The LF and HF powers were larger in voles than mice. The LF/HF ratio was thought to provide a convenient index of autonomic nervous balance and was smaller in voles than mice. The LF powers in both species were reduced by atropine, but propranolol reduced the LF power only in mice. The HF power was reduced by atropine only in voles. The intrinsic heart rate produced by a double blockade with atropine and propranolol in voles was almost the same as control levels, but in mice was lower than controls. The ratio of the LF and HF powers by a double blockade were almost the same as those of the administration of atropine in voles, but nearer to propranolol in mice. These results suggested that the parasympathetic nervous function was predominant in voles, but the sympathetic one was predominant in mice. |
format |
Article in Journal/Newspaper |
author |
Ishii, K. Kuwahara, M. Tsubone, H. Sugano, S. |
spellingShingle |
Ishii, K. Kuwahara, M. Tsubone, H. Sugano, S. Autonomic nervous function in mice and voles ( Microtus arvalis): investigation by power spectral analysis of heart rate variability |
author_facet |
Ishii, K. Kuwahara, M. Tsubone, H. Sugano, S. |
author_sort |
Ishii, K. |
title |
Autonomic nervous function in mice and voles ( Microtus arvalis): investigation by power spectral analysis of heart rate variability |
title_short |
Autonomic nervous function in mice and voles ( Microtus arvalis): investigation by power spectral analysis of heart rate variability |
title_full |
Autonomic nervous function in mice and voles ( Microtus arvalis): investigation by power spectral analysis of heart rate variability |
title_fullStr |
Autonomic nervous function in mice and voles ( Microtus arvalis): investigation by power spectral analysis of heart rate variability |
title_full_unstemmed |
Autonomic nervous function in mice and voles ( Microtus arvalis): investigation by power spectral analysis of heart rate variability |
title_sort |
autonomic nervous function in mice and voles ( microtus arvalis): investigation by power spectral analysis of heart rate variability |
publisher |
SAGE Publications |
publishDate |
1996 |
url |
http://dx.doi.org/10.1258/002367796780739880 https://journals.sagepub.com/doi/pdf/10.1258/002367796780739880 |
genre |
Microtus arvalis |
genre_facet |
Microtus arvalis |
op_source |
Laboratory Animals volume 30, issue 4, page 359-364 ISSN 0023-6772 1758-1117 |
op_rights |
https://journals.sagepub.com/page/policies/text-and-data-mining-license |
op_doi |
https://doi.org/10.1258/002367796780739880 |
container_title |
Laboratory Animals |
container_volume |
30 |
container_issue |
4 |
container_start_page |
359 |
op_container_end_page |
364 |
_version_ |
1812178763592499200 |