Serial electromyographic findings in Guillain-Barré syndrome patients
We sought to investigate electromyographic characteristics of Guillain-Barré syndrome (GBS) patients in the recovery phase by using serial electromyography (EMG). We included seven GBS patients and assessed their neurologic function at admission and 2, 3 and 6 months post onset using Hughes Function...
Published in: | European Journal of Inflammation |
---|---|
Main Authors: | , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
SAGE Publications
2018
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1177/2058739218793536 http://journals.sagepub.com/doi/pdf/10.1177/2058739218793536 http://journals.sagepub.com/doi/full-xml/10.1177/2058739218793536 |
id |
crsagepubl:10.1177/2058739218793536 |
---|---|
record_format |
openpolar |
spelling |
crsagepubl:10.1177/2058739218793536 2023-05-15T16:02:03+02:00 Serial electromyographic findings in Guillain-Barré syndrome patients Yang, Yumei Lu, Jing Bao, Huan 2018 http://dx.doi.org/10.1177/2058739218793536 http://journals.sagepub.com/doi/pdf/10.1177/2058739218793536 http://journals.sagepub.com/doi/full-xml/10.1177/2058739218793536 en eng SAGE Publications http://journals.sagepub.com/page/policies/text-and-data-mining-license European Journal of Inflammation volume 16, page 205873921879353 ISSN 2058-7392 2058-7392 Immunology Immunology and Allergy General Medicine journal-article 2018 crsagepubl https://doi.org/10.1177/2058739218793536 2022-04-14T04:35:31Z We sought to investigate electromyographic characteristics of Guillain-Barré syndrome (GBS) patients in the recovery phase by using serial electromyography (EMG). We included seven GBS patients and assessed their neurologic function at admission and 2, 3 and 6 months post onset using Hughes Functional Grading Scale scores. All patients underwent serial electromyographic assessment of compound muscle action potentials (CMAPs), mean conduction velocity (MCV), and distal motor latency (DML) of peripheral nerves. F wave was recorded of the median nerve and ulnar nerve. All seven patients had a Hughes Functional Grading Scale score between 3 and 6 at admission, while three patients at 2 months, one patient at 3 months, and no patient at 6 months post GBS onset had a Hughes Functional Grading Scale score between 3 and 6 ( P < 0.05). No F wave was elicited in 41.7% (20/48) of the motor nerves examined at admission, which declined to 25% at 6 months post GBS onset. Decreased amplitude in CMAPs was seen in 50% (24/48) of the motor nerves examined at admission, which decreased to 25% at 6 months ( P < 0.05). Moreover, 60.4% (29/48) of the motor nerves showed abnormal abduction velocity, which declined to 0% at 3 and 6 months post GBS onset ( P < 0.01). In conclusion, GBS patients exhibit a variable course in recovery of electromyographic parameters, and amplitude in CMAPs cannot fully reflect recovery of muscle tone. Conduction block is reversible and in line with rapid muscle tone recovery. Article in Journal/Newspaper DML SAGE Publications (via Crossref) Barré ENVELOPE(-68.550,-68.550,-67.500,-67.500) European Journal of Inflammation 16 205873921879353 |
institution |
Open Polar |
collection |
SAGE Publications (via Crossref) |
op_collection_id |
crsagepubl |
language |
English |
topic |
Immunology Immunology and Allergy General Medicine |
spellingShingle |
Immunology Immunology and Allergy General Medicine Yang, Yumei Lu, Jing Bao, Huan Serial electromyographic findings in Guillain-Barré syndrome patients |
topic_facet |
Immunology Immunology and Allergy General Medicine |
description |
We sought to investigate electromyographic characteristics of Guillain-Barré syndrome (GBS) patients in the recovery phase by using serial electromyography (EMG). We included seven GBS patients and assessed their neurologic function at admission and 2, 3 and 6 months post onset using Hughes Functional Grading Scale scores. All patients underwent serial electromyographic assessment of compound muscle action potentials (CMAPs), mean conduction velocity (MCV), and distal motor latency (DML) of peripheral nerves. F wave was recorded of the median nerve and ulnar nerve. All seven patients had a Hughes Functional Grading Scale score between 3 and 6 at admission, while three patients at 2 months, one patient at 3 months, and no patient at 6 months post GBS onset had a Hughes Functional Grading Scale score between 3 and 6 ( P < 0.05). No F wave was elicited in 41.7% (20/48) of the motor nerves examined at admission, which declined to 25% at 6 months post GBS onset. Decreased amplitude in CMAPs was seen in 50% (24/48) of the motor nerves examined at admission, which decreased to 25% at 6 months ( P < 0.05). Moreover, 60.4% (29/48) of the motor nerves showed abnormal abduction velocity, which declined to 0% at 3 and 6 months post GBS onset ( P < 0.01). In conclusion, GBS patients exhibit a variable course in recovery of electromyographic parameters, and amplitude in CMAPs cannot fully reflect recovery of muscle tone. Conduction block is reversible and in line with rapid muscle tone recovery. |
format |
Article in Journal/Newspaper |
author |
Yang, Yumei Lu, Jing Bao, Huan |
author_facet |
Yang, Yumei Lu, Jing Bao, Huan |
author_sort |
Yang, Yumei |
title |
Serial electromyographic findings in Guillain-Barré syndrome patients |
title_short |
Serial electromyographic findings in Guillain-Barré syndrome patients |
title_full |
Serial electromyographic findings in Guillain-Barré syndrome patients |
title_fullStr |
Serial electromyographic findings in Guillain-Barré syndrome patients |
title_full_unstemmed |
Serial electromyographic findings in Guillain-Barré syndrome patients |
title_sort |
serial electromyographic findings in guillain-barré syndrome patients |
publisher |
SAGE Publications |
publishDate |
2018 |
url |
http://dx.doi.org/10.1177/2058739218793536 http://journals.sagepub.com/doi/pdf/10.1177/2058739218793536 http://journals.sagepub.com/doi/full-xml/10.1177/2058739218793536 |
long_lat |
ENVELOPE(-68.550,-68.550,-67.500,-67.500) |
geographic |
Barré |
geographic_facet |
Barré |
genre |
DML |
genre_facet |
DML |
op_source |
European Journal of Inflammation volume 16, page 205873921879353 ISSN 2058-7392 2058-7392 |
op_rights |
http://journals.sagepub.com/page/policies/text-and-data-mining-license |
op_doi |
https://doi.org/10.1177/2058739218793536 |
container_title |
European Journal of Inflammation |
container_volume |
16 |
container_start_page |
205873921879353 |
_version_ |
1766397685703639040 |