Highly Efficient Lipase Catalyzed Monoaminolysis Reaction of Diesters with Benzylamine

• Published in: Natural Product Communications
• Main Authors: Valerio-Alfaro, Gerardo, Castillo-Carrasco, Patricia Harumi, Castellanos Onorio, Olaya Pirene, Naranjos, Jorge Bautista
• Format: Article in Journal/Newspaper
• Language: English
• Published: SAGE Publications 2019
• Subjects: Complementary and alternative medicine; Plant Science; Drug Discovery; Pharmacology; General Medicine; Rugosa; Antarc*; Antarctica
• Online Access: http://dx.doi.org/10.1177/1934578x19859980; http://journals.sagepub.com/doi/pdf/10.1177/1934578X19859980; http://journals.sagepub.com/doi/full-xml/10.1177/1934578X19859980

Preparation of amides by biocatalyzed aminolysis reactions has greatly increased because these processes play an important role in the preparation of some pharmaceutical products and their intermediates. A highly efficient synthesis of malonic (5), succinic (6), and malic (8) monoamide esters by des...