Influence of N -Deacetylation Conditions on Chitosan Production from α-Chitin
The physicochemical characteristics of chitosan differ with the preparation conditions. Thus, it is necessary to control the different parameters which influence the N-deacetylation reaction so as to produce chitosan with the characteristics required by its final applications. Samples of α-chitin us...
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crsagepubl:10.1177/1934578x0800300414 2023-05-15T14:12:50+02:00 Influence of N -Deacetylation Conditions on Chitosan Production from α-Chitin Galed, Gemma Diaz, Erika Goycoolea, Francisco M. Heras, Angeles 2008 http://dx.doi.org/10.1177/1934578x0800300414 http://journals.sagepub.com/doi/pdf/10.1177/1934578X0800300414 en eng SAGE Publications http://journals.sagepub.com/page/policies/text-and-data-mining-license Natural Product Communications volume 3, issue 4, page 1934578X0800300 ISSN 1934-578X 1555-9475 Complementary and alternative medicine Plant Science Drug Discovery Pharmacology General Medicine journal-article 2008 crsagepubl https://doi.org/10.1177/1934578x0800300414 2022-07-03T16:06:51Z The physicochemical characteristics of chitosan differ with the preparation conditions. Thus, it is necessary to control the different parameters which influence the N-deacetylation reaction so as to produce chitosan with the characteristics required by its final applications. Samples of α-chitin used in this report were obtained from Snow crab ( Paralomis granulosa) and King crab ( Lithodes antarcticus). These species are not commonly used in the production of chitosan, making it important to find the proper conditions for the reactions involved. After careful study of several different N-deacetylation conditions [80°, 90°, 100°, 110°C and 30%, 50%, 60%, 70% (w/v) of sodium hydroxide solution], it was demonstrated that, in the case of these species, 110°C was the most effective temperature under heterogeneous conditions at least for the first 10 minutes of the reaction. Also, a nitrogen environment to reduce the degradation of the polymer during the reaction was more effective than other methods proposed in the literature. Finally, use of 70% (w/v) sodium hydroxide solution let us obtain soluble products in the first minutes of the reaction without causing much degradation. Article in Journal/Newspaper Antarc* antarcticus Snow crab SAGE Publications (via Crossref) Natural Product Communications 3 4 1934578X0800300 |
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Open Polar |
collection |
SAGE Publications (via Crossref) |
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crsagepubl |
language |
English |
topic |
Complementary and alternative medicine Plant Science Drug Discovery Pharmacology General Medicine |
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Complementary and alternative medicine Plant Science Drug Discovery Pharmacology General Medicine Galed, Gemma Diaz, Erika Goycoolea, Francisco M. Heras, Angeles Influence of N -Deacetylation Conditions on Chitosan Production from α-Chitin |
topic_facet |
Complementary and alternative medicine Plant Science Drug Discovery Pharmacology General Medicine |
description |
The physicochemical characteristics of chitosan differ with the preparation conditions. Thus, it is necessary to control the different parameters which influence the N-deacetylation reaction so as to produce chitosan with the characteristics required by its final applications. Samples of α-chitin used in this report were obtained from Snow crab ( Paralomis granulosa) and King crab ( Lithodes antarcticus). These species are not commonly used in the production of chitosan, making it important to find the proper conditions for the reactions involved. After careful study of several different N-deacetylation conditions [80°, 90°, 100°, 110°C and 30%, 50%, 60%, 70% (w/v) of sodium hydroxide solution], it was demonstrated that, in the case of these species, 110°C was the most effective temperature under heterogeneous conditions at least for the first 10 minutes of the reaction. Also, a nitrogen environment to reduce the degradation of the polymer during the reaction was more effective than other methods proposed in the literature. Finally, use of 70% (w/v) sodium hydroxide solution let us obtain soluble products in the first minutes of the reaction without causing much degradation. |
format |
Article in Journal/Newspaper |
author |
Galed, Gemma Diaz, Erika Goycoolea, Francisco M. Heras, Angeles |
author_facet |
Galed, Gemma Diaz, Erika Goycoolea, Francisco M. Heras, Angeles |
author_sort |
Galed, Gemma |
title |
Influence of N -Deacetylation Conditions on Chitosan Production from α-Chitin |
title_short |
Influence of N -Deacetylation Conditions on Chitosan Production from α-Chitin |
title_full |
Influence of N -Deacetylation Conditions on Chitosan Production from α-Chitin |
title_fullStr |
Influence of N -Deacetylation Conditions on Chitosan Production from α-Chitin |
title_full_unstemmed |
Influence of N -Deacetylation Conditions on Chitosan Production from α-Chitin |
title_sort |
influence of n -deacetylation conditions on chitosan production from α-chitin |
publisher |
SAGE Publications |
publishDate |
2008 |
url |
http://dx.doi.org/10.1177/1934578x0800300414 http://journals.sagepub.com/doi/pdf/10.1177/1934578X0800300414 |
genre |
Antarc* antarcticus Snow crab |
genre_facet |
Antarc* antarcticus Snow crab |
op_source |
Natural Product Communications volume 3, issue 4, page 1934578X0800300 ISSN 1934-578X 1555-9475 |
op_rights |
http://journals.sagepub.com/page/policies/text-and-data-mining-license |
op_doi |
https://doi.org/10.1177/1934578x0800300414 |
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Natural Product Communications |
container_volume |
3 |
container_issue |
4 |
container_start_page |
1934578X0800300 |
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1766285183803195392 |