An Investigation of Potential Health Risks from Zoonotic Bacterial Pathogens Associated with Farm Rats
Background: The 21st century has seen a wide range of diseases resulting from zoonotic infections, of which bacterial infections have led to outbreaks of food-borne diseases. Aim: The study looks at bacterial pathogen carriage by farm rats and their antimicrobial susceptibility, with the view of pro...
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crsagepubl:10.1177/1178630220942240 2024-09-09T20:05:03+00:00 An Investigation of Potential Health Risks from Zoonotic Bacterial Pathogens Associated with Farm Rats Badger-Emeka, Lorina Al-Mulhim, Yasmeen Al-Muyidi, Fatimah Busuhail, Maram Alkhalifah, Salma AlEid, Norah 2020 http://dx.doi.org/10.1177/1178630220942240 http://journals.sagepub.com/doi/pdf/10.1177/1178630220942240 http://journals.sagepub.com/doi/full-xml/10.1177/1178630220942240 en eng SAGE Publications https://creativecommons.org/licenses/by-nc/4.0/ Environmental Health Insights volume 14, page 117863022094224 ISSN 1178-6302 1178-6302 journal-article 2020 crsagepubl https://doi.org/10.1177/1178630220942240 2024-08-19T04:29:05Z Background: The 21st century has seen a wide range of diseases resulting from zoonotic infections, of which bacterial infections have led to outbreaks of food-borne diseases. Aim: The study looks at bacterial pathogen carriage by farm rats and their antimicrobial susceptibility, with the view of providing insights for antimicrobial surveillance. Method: Farm rats of Rattus rattus species where randomly collected alive from farms in Al-Ahsa using food baits. They were anaesthetize with urethane within 4 h of collection and were unconscious for the collection of samples. Basic bacteriological culturing methods were used for culturing of bacterial isolates on selective media while the Vitek 2 compact automated system (BioMerieux, Marcy L’Etoile, France) was used for bacteria identification and antimicrobial susceptibility test. Obtained data were analysed using chi-square and paired t-test with significant difference between sensitive and resistance to antimicrobial susceptibility taken at P < .05. Results: Isolated Gramme-negative pathogenic bacteria included strains of Escherichia coli, Pseudomonas oryzihabitans, strains of Pseudomonas aeruginosa, and Salmonella. For the Gramme-positive bacteria, 4 strains of Staphylococcus aureus were encountered. Other Gramme-positive bacteria were coagulase-negative Staphylococcal species (CoNS) as well as Staphylococcus lugdunensis. There was a 100% resistance to the penicillins and a high resistance to imipenem (71%) by the Staphylococcal isolates. Resistance was also high against the β-lactams by the Gramme-positive bacteria isolates. For the Gramme-negative bacteria, there was a higher than 50% resistance by the isolates against the following antibiotics: ampicillin (78%), amoxicillin/clavulanic acid (67%), cefotaxime (77%), ceftazidime (67%), cefepime (78%), norfloxacin (67%), nitrofurantoin (67%), and trimethoprim/sulfamethoxazole (78%). Conclusion: The results showed high antimicrobial resistance that will need monitoring for control of spread from farm rats to ... Article in Journal/Newspaper Rattus rattus SAGE Publications Environmental Health Insights 14 117863022094224 |
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English |
description |
Background: The 21st century has seen a wide range of diseases resulting from zoonotic infections, of which bacterial infections have led to outbreaks of food-borne diseases. Aim: The study looks at bacterial pathogen carriage by farm rats and their antimicrobial susceptibility, with the view of providing insights for antimicrobial surveillance. Method: Farm rats of Rattus rattus species where randomly collected alive from farms in Al-Ahsa using food baits. They were anaesthetize with urethane within 4 h of collection and were unconscious for the collection of samples. Basic bacteriological culturing methods were used for culturing of bacterial isolates on selective media while the Vitek 2 compact automated system (BioMerieux, Marcy L’Etoile, France) was used for bacteria identification and antimicrobial susceptibility test. Obtained data were analysed using chi-square and paired t-test with significant difference between sensitive and resistance to antimicrobial susceptibility taken at P < .05. Results: Isolated Gramme-negative pathogenic bacteria included strains of Escherichia coli, Pseudomonas oryzihabitans, strains of Pseudomonas aeruginosa, and Salmonella. For the Gramme-positive bacteria, 4 strains of Staphylococcus aureus were encountered. Other Gramme-positive bacteria were coagulase-negative Staphylococcal species (CoNS) as well as Staphylococcus lugdunensis. There was a 100% resistance to the penicillins and a high resistance to imipenem (71%) by the Staphylococcal isolates. Resistance was also high against the β-lactams by the Gramme-positive bacteria isolates. For the Gramme-negative bacteria, there was a higher than 50% resistance by the isolates against the following antibiotics: ampicillin (78%), amoxicillin/clavulanic acid (67%), cefotaxime (77%), ceftazidime (67%), cefepime (78%), norfloxacin (67%), nitrofurantoin (67%), and trimethoprim/sulfamethoxazole (78%). Conclusion: The results showed high antimicrobial resistance that will need monitoring for control of spread from farm rats to ... |
format |
Article in Journal/Newspaper |
author |
Badger-Emeka, Lorina Al-Mulhim, Yasmeen Al-Muyidi, Fatimah Busuhail, Maram Alkhalifah, Salma AlEid, Norah |
spellingShingle |
Badger-Emeka, Lorina Al-Mulhim, Yasmeen Al-Muyidi, Fatimah Busuhail, Maram Alkhalifah, Salma AlEid, Norah An Investigation of Potential Health Risks from Zoonotic Bacterial Pathogens Associated with Farm Rats |
author_facet |
Badger-Emeka, Lorina Al-Mulhim, Yasmeen Al-Muyidi, Fatimah Busuhail, Maram Alkhalifah, Salma AlEid, Norah |
author_sort |
Badger-Emeka, Lorina |
title |
An Investigation of Potential Health Risks from Zoonotic Bacterial Pathogens Associated with Farm Rats |
title_short |
An Investigation of Potential Health Risks from Zoonotic Bacterial Pathogens Associated with Farm Rats |
title_full |
An Investigation of Potential Health Risks from Zoonotic Bacterial Pathogens Associated with Farm Rats |
title_fullStr |
An Investigation of Potential Health Risks from Zoonotic Bacterial Pathogens Associated with Farm Rats |
title_full_unstemmed |
An Investigation of Potential Health Risks from Zoonotic Bacterial Pathogens Associated with Farm Rats |
title_sort |
investigation of potential health risks from zoonotic bacterial pathogens associated with farm rats |
publisher |
SAGE Publications |
publishDate |
2020 |
url |
http://dx.doi.org/10.1177/1178630220942240 http://journals.sagepub.com/doi/pdf/10.1177/1178630220942240 http://journals.sagepub.com/doi/full-xml/10.1177/1178630220942240 |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_source |
Environmental Health Insights volume 14, page 117863022094224 ISSN 1178-6302 1178-6302 |
op_rights |
https://creativecommons.org/licenses/by-nc/4.0/ |
op_doi |
https://doi.org/10.1177/1178630220942240 |
container_title |
Environmental Health Insights |
container_volume |
14 |
container_start_page |
117863022094224 |
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1809937368148344832 |