Fish Oil: Effectiveness as a Dietary Supplement in the Prevention of Heart Disease
The low incidence of reported heart attacks and cardiovascular-related deaths in Greenland Eskimos and the Japanese has generated interest in the possible protective effect of their diet, which is made up primarily of fish and related marine foods. This paper reviews the current evidence for reducin...
Published in: | Drug Intelligence & Clinical Pharmacy |
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Language: | English |
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SAGE Publications
1987
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Online Access: | http://dx.doi.org/10.1177/1060028087021007-803 http://journals.sagepub.com/doi/pdf/10.1177/1060028087021007-803 |
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crsagepubl:10.1177/1060028087021007-803 2023-05-15T16:07:40+02:00 Fish Oil: Effectiveness as a Dietary Supplement in the Prevention of Heart Disease Zeller, Frederick P. Spears, Catlin 1987 http://dx.doi.org/10.1177/1060028087021007-803 http://journals.sagepub.com/doi/pdf/10.1177/1060028087021007-803 en eng SAGE Publications http://journals.sagepub.com/page/policies/text-and-data-mining-license Drug Intelligence & Clinical Pharmacy volume 21, issue 7-8, page 584-589 ISSN 0012-6578 Pharmacology (medical) General Pharmacology, Toxicology and Pharmaceutics journal-article 1987 crsagepubl https://doi.org/10.1177/1060028087021007-803 2022-08-12T11:31:22Z The low incidence of reported heart attacks and cardiovascular-related deaths in Greenland Eskimos and the Japanese has generated interest in the possible protective effect of their diet, which is made up primarily of fish and related marine foods. This paper reviews the current evidence for reducing the risk of cardiovascular disease with fish-oil supplementation, and discusses related clinical data to support the mechanisms proposed. Included is evidence that fish oil can lower certain serum lipid levels, prolong bleeding time, and reduce systolic blood pressure when consumed in moderately large doses. Information on safety and side effects is also presented, such as a possible increase in serum cholesterol levels and annoying side effects that may severely limit widespread use of this food supplement. Presently it remains unanswered whether fish oil should be recommended as a dietary supplement for the prevention and/or treatment of hypercholesterolemia and associated coronary artery disease. Further research is required to demonstrate a clear reduction in cardiovascular mortality before a uniform recommendation can be made. Article in Journal/Newspaper eskimo* Greenland SAGE Publications (via Crossref) Greenland Drug Intelligence & Clinical Pharmacy 21 7-8 584 589 |
institution |
Open Polar |
collection |
SAGE Publications (via Crossref) |
op_collection_id |
crsagepubl |
language |
English |
topic |
Pharmacology (medical) General Pharmacology, Toxicology and Pharmaceutics |
spellingShingle |
Pharmacology (medical) General Pharmacology, Toxicology and Pharmaceutics Zeller, Frederick P. Spears, Catlin Fish Oil: Effectiveness as a Dietary Supplement in the Prevention of Heart Disease |
topic_facet |
Pharmacology (medical) General Pharmacology, Toxicology and Pharmaceutics |
description |
The low incidence of reported heart attacks and cardiovascular-related deaths in Greenland Eskimos and the Japanese has generated interest in the possible protective effect of their diet, which is made up primarily of fish and related marine foods. This paper reviews the current evidence for reducing the risk of cardiovascular disease with fish-oil supplementation, and discusses related clinical data to support the mechanisms proposed. Included is evidence that fish oil can lower certain serum lipid levels, prolong bleeding time, and reduce systolic blood pressure when consumed in moderately large doses. Information on safety and side effects is also presented, such as a possible increase in serum cholesterol levels and annoying side effects that may severely limit widespread use of this food supplement. Presently it remains unanswered whether fish oil should be recommended as a dietary supplement for the prevention and/or treatment of hypercholesterolemia and associated coronary artery disease. Further research is required to demonstrate a clear reduction in cardiovascular mortality before a uniform recommendation can be made. |
format |
Article in Journal/Newspaper |
author |
Zeller, Frederick P. Spears, Catlin |
author_facet |
Zeller, Frederick P. Spears, Catlin |
author_sort |
Zeller, Frederick P. |
title |
Fish Oil: Effectiveness as a Dietary Supplement in the Prevention of Heart Disease |
title_short |
Fish Oil: Effectiveness as a Dietary Supplement in the Prevention of Heart Disease |
title_full |
Fish Oil: Effectiveness as a Dietary Supplement in the Prevention of Heart Disease |
title_fullStr |
Fish Oil: Effectiveness as a Dietary Supplement in the Prevention of Heart Disease |
title_full_unstemmed |
Fish Oil: Effectiveness as a Dietary Supplement in the Prevention of Heart Disease |
title_sort |
fish oil: effectiveness as a dietary supplement in the prevention of heart disease |
publisher |
SAGE Publications |
publishDate |
1987 |
url |
http://dx.doi.org/10.1177/1060028087021007-803 http://journals.sagepub.com/doi/pdf/10.1177/1060028087021007-803 |
geographic |
Greenland |
geographic_facet |
Greenland |
genre |
eskimo* Greenland |
genre_facet |
eskimo* Greenland |
op_source |
Drug Intelligence & Clinical Pharmacy volume 21, issue 7-8, page 584-589 ISSN 0012-6578 |
op_rights |
http://journals.sagepub.com/page/policies/text-and-data-mining-license |
op_doi |
https://doi.org/10.1177/1060028087021007-803 |
container_title |
Drug Intelligence & Clinical Pharmacy |
container_volume |
21 |
container_issue |
7-8 |
container_start_page |
584 |
op_container_end_page |
589 |
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1766403766450388992 |