Presumed Primary Muscular Lymphoma in a Dog
A case of presumed primary muscular lymphoma in an 8-year-old, intact, male Newfoundland dog is reported. The dog was presented for evaluation of an infiltrating ventral cervical mass, respiratory distress, and anorexia of 1-month duration. Fine-needle aspiration of the mass revealed anaplastic larg...
Published in: | Journal of Veterinary Diagnostic Investigation |
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crsagepubl:10.1177/104063870802000621 2024-09-09T19:53:43+00:00 Presumed Primary Muscular Lymphoma in a Dog Thuilliez, Céline Watrelot-Virieux, Dorothée Chanut, Franck Fournel-Fleury, Corinne Ponce, Frédérique Marchal, Thierry 2008 http://dx.doi.org/10.1177/104063870802000621 http://journals.sagepub.com/doi/pdf/10.1177/104063870802000621 http://journals.sagepub.com/doi/full-xml/10.1177/104063870802000621 en eng SAGE Publications http://journals.sagepub.com/page/policies/text-and-data-mining-license Journal of Veterinary Diagnostic Investigation volume 20, issue 6, page 824-826 ISSN 1040-6387 1943-4936 journal-article 2008 crsagepubl https://doi.org/10.1177/104063870802000621 2024-07-22T04:32:57Z A case of presumed primary muscular lymphoma in an 8-year-old, intact, male Newfoundland dog is reported. The dog was presented for evaluation of an infiltrating ventral cervical mass, respiratory distress, and anorexia of 1-month duration. Fine-needle aspiration of the mass revealed anaplastic large cell lymphoma. Despite chemotherapy, health status declined and the animal was euthanized a few weeks later. At necropsy, the mass infiltrated the cervical muscles and extended ventrally to the left forelimb and cranially to the tongue and laryngeal musculature. Other muscles were infiltrated by the same neoplasm (diaphragm and intercostal, abdominal, and gluteal muscles) indicating a probable multicentric origin. Histological examination confirmed the diagnosis of anaplastic large cell lymphoma, which showed a strong muscular tropism. Immunohistochemical staining revealed neoplastic cell reactivity for cluster of differentiation 3 (CD3) and Ki-67 antigens (70% and 90%, respectively). The neoplastic cells were negative for CD79a. The presumed histological diagnosis in this dog was primary muscular anaplastic large T-cell lymphoma. Article in Journal/Newspaper Newfoundland SAGE Publications Journal of Veterinary Diagnostic Investigation 20 6 824 826 |
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English |
description |
A case of presumed primary muscular lymphoma in an 8-year-old, intact, male Newfoundland dog is reported. The dog was presented for evaluation of an infiltrating ventral cervical mass, respiratory distress, and anorexia of 1-month duration. Fine-needle aspiration of the mass revealed anaplastic large cell lymphoma. Despite chemotherapy, health status declined and the animal was euthanized a few weeks later. At necropsy, the mass infiltrated the cervical muscles and extended ventrally to the left forelimb and cranially to the tongue and laryngeal musculature. Other muscles were infiltrated by the same neoplasm (diaphragm and intercostal, abdominal, and gluteal muscles) indicating a probable multicentric origin. Histological examination confirmed the diagnosis of anaplastic large cell lymphoma, which showed a strong muscular tropism. Immunohistochemical staining revealed neoplastic cell reactivity for cluster of differentiation 3 (CD3) and Ki-67 antigens (70% and 90%, respectively). The neoplastic cells were negative for CD79a. The presumed histological diagnosis in this dog was primary muscular anaplastic large T-cell lymphoma. |
format |
Article in Journal/Newspaper |
author |
Thuilliez, Céline Watrelot-Virieux, Dorothée Chanut, Franck Fournel-Fleury, Corinne Ponce, Frédérique Marchal, Thierry |
spellingShingle |
Thuilliez, Céline Watrelot-Virieux, Dorothée Chanut, Franck Fournel-Fleury, Corinne Ponce, Frédérique Marchal, Thierry Presumed Primary Muscular Lymphoma in a Dog |
author_facet |
Thuilliez, Céline Watrelot-Virieux, Dorothée Chanut, Franck Fournel-Fleury, Corinne Ponce, Frédérique Marchal, Thierry |
author_sort |
Thuilliez, Céline |
title |
Presumed Primary Muscular Lymphoma in a Dog |
title_short |
Presumed Primary Muscular Lymphoma in a Dog |
title_full |
Presumed Primary Muscular Lymphoma in a Dog |
title_fullStr |
Presumed Primary Muscular Lymphoma in a Dog |
title_full_unstemmed |
Presumed Primary Muscular Lymphoma in a Dog |
title_sort |
presumed primary muscular lymphoma in a dog |
publisher |
SAGE Publications |
publishDate |
2008 |
url |
http://dx.doi.org/10.1177/104063870802000621 http://journals.sagepub.com/doi/pdf/10.1177/104063870802000621 http://journals.sagepub.com/doi/full-xml/10.1177/104063870802000621 |
genre |
Newfoundland |
genre_facet |
Newfoundland |
op_source |
Journal of Veterinary Diagnostic Investigation volume 20, issue 6, page 824-826 ISSN 1040-6387 1943-4936 |
op_rights |
http://journals.sagepub.com/page/policies/text-and-data-mining-license |
op_doi |
https://doi.org/10.1177/104063870802000621 |
container_title |
Journal of Veterinary Diagnostic Investigation |
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20 |
container_issue |
6 |
container_start_page |
824 |
op_container_end_page |
826 |
_version_ |
1809923173469126656 |