The pH and Hydrogen Ion Content of Stored A.C.D. Blood
The metabolic and respiratory components of the hydrogen ion content of A.C.D. blood was directly measured by in vitro titration at controlled partial pressures of carbon dioxide. Blood stored for periods of up to 20 days had a mean pH of 6·53. The mean metabolic hydrogen ion excess was 37 mEq/litre...
Published in: | Anaesthesia and Intensive Care |
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Language: | English |
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SAGE Publications
1974
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Online Access: | http://dx.doi.org/10.1177/0310057x7400200309 http://journals.sagepub.com/doi/pdf/10.1177/0310057X7400200309 |
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crsagepubl:10.1177/0310057x7400200309 2024-09-15T18:01:38+00:00 The pH and Hydrogen Ion Content of Stored A.C.D. Blood Gaudry, P. L. Duffy, C. Joseph, D. 1974 http://dx.doi.org/10.1177/0310057x7400200309 http://journals.sagepub.com/doi/pdf/10.1177/0310057X7400200309 en eng SAGE Publications http://journals.sagepub.com/page/policies/text-and-data-mining-license Anaesthesia and Intensive Care volume 2, issue 3, page 247-250 ISSN 0310-057X 1448-0271 journal-article 1974 crsagepubl https://doi.org/10.1177/0310057x7400200309 2024-08-12T04:32:36Z The metabolic and respiratory components of the hydrogen ion content of A.C.D. blood was directly measured by in vitro titration at controlled partial pressures of carbon dioxide. Blood stored for periods of up to 20 days had a mean pH of 6·53. The mean metabolic hydrogen ion excess was 37 mEq/litre and the mean respiratory hydrogen ion excess (carbonic acid) was 98 mEq/litre. The pH and hydrogen ion excess were not significantly related to duration of storage. Both metabolic and respiratory acidosis may occur in recipients of these hydrogen ion loads. In addition, sodium citrate in A.C.D. solution is metabolized in vivo to sodium bicarbonate. Clinically, a variable state of acid-base imbalance may result from the transfusion of A.C.D. blood until homeostasis is restored by renal and respiratory excretion of the acid and base loads. Article in Journal/Newspaper Carbonic acid SAGE Publications Anaesthesia and Intensive Care 2 3 247 250 |
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English |
description |
The metabolic and respiratory components of the hydrogen ion content of A.C.D. blood was directly measured by in vitro titration at controlled partial pressures of carbon dioxide. Blood stored for periods of up to 20 days had a mean pH of 6·53. The mean metabolic hydrogen ion excess was 37 mEq/litre and the mean respiratory hydrogen ion excess (carbonic acid) was 98 mEq/litre. The pH and hydrogen ion excess were not significantly related to duration of storage. Both metabolic and respiratory acidosis may occur in recipients of these hydrogen ion loads. In addition, sodium citrate in A.C.D. solution is metabolized in vivo to sodium bicarbonate. Clinically, a variable state of acid-base imbalance may result from the transfusion of A.C.D. blood until homeostasis is restored by renal and respiratory excretion of the acid and base loads. |
format |
Article in Journal/Newspaper |
author |
Gaudry, P. L. Duffy, C. Joseph, D. |
spellingShingle |
Gaudry, P. L. Duffy, C. Joseph, D. The pH and Hydrogen Ion Content of Stored A.C.D. Blood |
author_facet |
Gaudry, P. L. Duffy, C. Joseph, D. |
author_sort |
Gaudry, P. L. |
title |
The pH and Hydrogen Ion Content of Stored A.C.D. Blood |
title_short |
The pH and Hydrogen Ion Content of Stored A.C.D. Blood |
title_full |
The pH and Hydrogen Ion Content of Stored A.C.D. Blood |
title_fullStr |
The pH and Hydrogen Ion Content of Stored A.C.D. Blood |
title_full_unstemmed |
The pH and Hydrogen Ion Content of Stored A.C.D. Blood |
title_sort |
ph and hydrogen ion content of stored a.c.d. blood |
publisher |
SAGE Publications |
publishDate |
1974 |
url |
http://dx.doi.org/10.1177/0310057x7400200309 http://journals.sagepub.com/doi/pdf/10.1177/0310057X7400200309 |
genre |
Carbonic acid |
genre_facet |
Carbonic acid |
op_source |
Anaesthesia and Intensive Care volume 2, issue 3, page 247-250 ISSN 0310-057X 1448-0271 |
op_rights |
http://journals.sagepub.com/page/policies/text-and-data-mining-license |
op_doi |
https://doi.org/10.1177/0310057x7400200309 |
container_title |
Anaesthesia and Intensive Care |
container_volume |
2 |
container_issue |
3 |
container_start_page |
247 |
op_container_end_page |
250 |
_version_ |
1810438735722971136 |