Immunohistochemical, Ultrastructural, and Hormonal Studies on the Endocrine Pancreas of Voles ( Microtus arvalis) with Monosodium Aspartate-induced Diabetes

• Published in: Veterinary Pathology
• Main Authors: Sasaki, M., Arai, T., Usui, T., Oki, Y.
• Format: Article in Journal/Newspaper
• Language: English
• Published: SAGE Publications 1991
• Subjects: The Islets; Microtus arvalis
• Online Access: http://dx.doi.org/10.1177/030098589102800606; https://journals.sagepub.com/doi/pdf/10.1177/030098589102800606

A single subcutaneous administration of monosodium aspartate (MSA) to 30 neonatal voles, Microtus arvalis Pallas, induced a diabetes mellitus in 50% of the treated animals in early adulthood. The voles (18 males and 12 females) were weaned at 3 weeks of age and fed pellets for Herbivora and cubed ha...