Disseminated Intravascular Coagulation in “Hitra Disease” (Hemorrhagic Syndrome) in Farmed Atlantic Salmon
Necropsy findings in adult salmon with subclinical “Hitra disease” (hemorrhagic syndrome) varied from negligible to hemorrhagic diathesis with generalized edema. By light microscopy, minute vessels were dilated, arterioles had mural necrosis, and thrombi were present. Occlusions consisted of fused e...
Published in: | Veterinary Pathology |
---|---|
Main Authors: | , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
SAGE Publications
1987
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1177/030098588702400503 http://journals.sagepub.com/doi/pdf/10.1177/030098588702400503 |
id |
crsagepubl:10.1177/030098588702400503 |
---|---|
record_format |
openpolar |
spelling |
crsagepubl:10.1177/030098588702400503 2023-05-15T15:30:44+02:00 Disseminated Intravascular Coagulation in “Hitra Disease” (Hemorrhagic Syndrome) in Farmed Atlantic Salmon Salte, R. Nafstad, P. Åsgård, T. 1987 http://dx.doi.org/10.1177/030098588702400503 http://journals.sagepub.com/doi/pdf/10.1177/030098588702400503 en eng SAGE Publications http://journals.sagepub.com/page/policies/text-and-data-mining-license Veterinary Pathology volume 24, issue 5, page 378-385 ISSN 0300-9858 1544-2217 General Veterinary journal-article 1987 crsagepubl https://doi.org/10.1177/030098588702400503 2022-08-12T11:30:21Z Necropsy findings in adult salmon with subclinical “Hitra disease” (hemorrhagic syndrome) varied from negligible to hemorrhagic diathesis with generalized edema. By light microscopy, minute vessels were dilated, arterioles had mural necrosis, and thrombi were present. Occlusions consisted of fused erythrocytes and fibrin. Ultrastructurally, endothelial nuclei were pyknotic with condensed chromatin. The cytoplasm contained numerous laminar structures and electron-dense particles. Damaged erythrocytes adhered to the degenerated endothelium, and coalesced erythrocytes had formed mural thrombi or filled the vascular lumen. Microthrombi were frequently seen. There were no thrombocytes in the thrombi, which consisted of erythrocytes or reticulocytes. Clinically healthy farmed salmon parr showed the same disorders as did adults, but to a far lesser degree. Wild salmon parr had normal microvasculature. Results indicate that disseminated intravascular coagulation (DIC) occurs in “Hitra disease” in farmed Atlantic salmon. Article in Journal/Newspaper Atlantic salmon SAGE Publications (via Crossref) Hitra ENVELOPE(8.756,8.756,63.544,63.544) Veterinary Pathology 24 5 378 385 |
institution |
Open Polar |
collection |
SAGE Publications (via Crossref) |
op_collection_id |
crsagepubl |
language |
English |
topic |
General Veterinary |
spellingShingle |
General Veterinary Salte, R. Nafstad, P. Åsgård, T. Disseminated Intravascular Coagulation in “Hitra Disease” (Hemorrhagic Syndrome) in Farmed Atlantic Salmon |
topic_facet |
General Veterinary |
description |
Necropsy findings in adult salmon with subclinical “Hitra disease” (hemorrhagic syndrome) varied from negligible to hemorrhagic diathesis with generalized edema. By light microscopy, minute vessels were dilated, arterioles had mural necrosis, and thrombi were present. Occlusions consisted of fused erythrocytes and fibrin. Ultrastructurally, endothelial nuclei were pyknotic with condensed chromatin. The cytoplasm contained numerous laminar structures and electron-dense particles. Damaged erythrocytes adhered to the degenerated endothelium, and coalesced erythrocytes had formed mural thrombi or filled the vascular lumen. Microthrombi were frequently seen. There were no thrombocytes in the thrombi, which consisted of erythrocytes or reticulocytes. Clinically healthy farmed salmon parr showed the same disorders as did adults, but to a far lesser degree. Wild salmon parr had normal microvasculature. Results indicate that disseminated intravascular coagulation (DIC) occurs in “Hitra disease” in farmed Atlantic salmon. |
format |
Article in Journal/Newspaper |
author |
Salte, R. Nafstad, P. Åsgård, T. |
author_facet |
Salte, R. Nafstad, P. Åsgård, T. |
author_sort |
Salte, R. |
title |
Disseminated Intravascular Coagulation in “Hitra Disease” (Hemorrhagic Syndrome) in Farmed Atlantic Salmon |
title_short |
Disseminated Intravascular Coagulation in “Hitra Disease” (Hemorrhagic Syndrome) in Farmed Atlantic Salmon |
title_full |
Disseminated Intravascular Coagulation in “Hitra Disease” (Hemorrhagic Syndrome) in Farmed Atlantic Salmon |
title_fullStr |
Disseminated Intravascular Coagulation in “Hitra Disease” (Hemorrhagic Syndrome) in Farmed Atlantic Salmon |
title_full_unstemmed |
Disseminated Intravascular Coagulation in “Hitra Disease” (Hemorrhagic Syndrome) in Farmed Atlantic Salmon |
title_sort |
disseminated intravascular coagulation in “hitra disease” (hemorrhagic syndrome) in farmed atlantic salmon |
publisher |
SAGE Publications |
publishDate |
1987 |
url |
http://dx.doi.org/10.1177/030098588702400503 http://journals.sagepub.com/doi/pdf/10.1177/030098588702400503 |
long_lat |
ENVELOPE(8.756,8.756,63.544,63.544) |
geographic |
Hitra |
geographic_facet |
Hitra |
genre |
Atlantic salmon |
genre_facet |
Atlantic salmon |
op_source |
Veterinary Pathology volume 24, issue 5, page 378-385 ISSN 0300-9858 1544-2217 |
op_rights |
http://journals.sagepub.com/page/policies/text-and-data-mining-license |
op_doi |
https://doi.org/10.1177/030098588702400503 |
container_title |
Veterinary Pathology |
container_volume |
24 |
container_issue |
5 |
container_start_page |
378 |
op_container_end_page |
385 |
_version_ |
1766361190162759680 |