Clinical, Gross, and Histological Findings in Herring Gulls and Atlantic Puffins that Ingested Prudhoe Bay Crude Oil
Oral doses of 0, 1, 4, 5, 10, or 20 ml of Prudhoe Bay crude oil/kg body weight/day were given to herring gull and Atlantic puffin nestlings for 5 to 7 consecutive days. Gulls defecated substantial amounts of oil within 10 to 15 minutes after receiving a dose. Clinical signs and lesions occurred only...
Published in: | Veterinary Pathology |
---|---|
Main Author: | |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
SAGE Publications
1986
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1177/030098588602300305 http://journals.sagepub.com/doi/pdf/10.1177/030098588602300305 |
id |
crsagepubl:10.1177/030098588602300305 |
---|---|
record_format |
openpolar |
spelling |
crsagepubl:10.1177/030098588602300305 2024-05-19T07:37:10+00:00 Clinical, Gross, and Histological Findings in Herring Gulls and Atlantic Puffins that Ingested Prudhoe Bay Crude Oil Leighton, F. A. 1986 http://dx.doi.org/10.1177/030098588602300305 http://journals.sagepub.com/doi/pdf/10.1177/030098588602300305 en eng SAGE Publications http://journals.sagepub.com/page/policies/text-and-data-mining-license Veterinary Pathology volume 23, issue 3, page 254-263 ISSN 0300-9858 1544-2217 journal-article 1986 crsagepubl https://doi.org/10.1177/030098588602300305 2024-05-02T09:39:34Z Oral doses of 0, 1, 4, 5, 10, or 20 ml of Prudhoe Bay crude oil/kg body weight/day were given to herring gull and Atlantic puffin nestlings for 5 to 7 consecutive days. Gulls defecated substantial amounts of oil within 10 to 15 minutes after receiving a dose. Clinical signs and lesions occurred only in birds given ≥ 10 ml oil/kg body weight/day. Gulls consumed less food and lost weight. Two categories of lesions were observed: those considered secondary to a primary toxic hemolytic disease, and those considered nonspecific reactions to stress. The former included phagocytosis of degenerate erythrocytes in the liver and spleen, hemoglobin resorption droplets in renal proximal tubule cells, and erythroid hyperplasia in the bone marrow; the latter included lymphocyte depletion in primary lymphoid tissues, an increase in heterophil: lymphocyte ratio in peripheral blood, lipid depletion and necrosis in adrenal steroidogenic cells, and an increased prevalence and severity of lesions in the bursa of Fabricius. These findings indicated that the primary target of oil toxicity was the peripheral red blood cell, but that significant stress-related lesions were also associated with ingestion of oil. Article in Journal/Newspaper Atlantic puffin Prudhoe Bay SAGE Publications Veterinary Pathology 23 3 254 263 |
institution |
Open Polar |
collection |
SAGE Publications |
op_collection_id |
crsagepubl |
language |
English |
description |
Oral doses of 0, 1, 4, 5, 10, or 20 ml of Prudhoe Bay crude oil/kg body weight/day were given to herring gull and Atlantic puffin nestlings for 5 to 7 consecutive days. Gulls defecated substantial amounts of oil within 10 to 15 minutes after receiving a dose. Clinical signs and lesions occurred only in birds given ≥ 10 ml oil/kg body weight/day. Gulls consumed less food and lost weight. Two categories of lesions were observed: those considered secondary to a primary toxic hemolytic disease, and those considered nonspecific reactions to stress. The former included phagocytosis of degenerate erythrocytes in the liver and spleen, hemoglobin resorption droplets in renal proximal tubule cells, and erythroid hyperplasia in the bone marrow; the latter included lymphocyte depletion in primary lymphoid tissues, an increase in heterophil: lymphocyte ratio in peripheral blood, lipid depletion and necrosis in adrenal steroidogenic cells, and an increased prevalence and severity of lesions in the bursa of Fabricius. These findings indicated that the primary target of oil toxicity was the peripheral red blood cell, but that significant stress-related lesions were also associated with ingestion of oil. |
format |
Article in Journal/Newspaper |
author |
Leighton, F. A. |
spellingShingle |
Leighton, F. A. Clinical, Gross, and Histological Findings in Herring Gulls and Atlantic Puffins that Ingested Prudhoe Bay Crude Oil |
author_facet |
Leighton, F. A. |
author_sort |
Leighton, F. A. |
title |
Clinical, Gross, and Histological Findings in Herring Gulls and Atlantic Puffins that Ingested Prudhoe Bay Crude Oil |
title_short |
Clinical, Gross, and Histological Findings in Herring Gulls and Atlantic Puffins that Ingested Prudhoe Bay Crude Oil |
title_full |
Clinical, Gross, and Histological Findings in Herring Gulls and Atlantic Puffins that Ingested Prudhoe Bay Crude Oil |
title_fullStr |
Clinical, Gross, and Histological Findings in Herring Gulls and Atlantic Puffins that Ingested Prudhoe Bay Crude Oil |
title_full_unstemmed |
Clinical, Gross, and Histological Findings in Herring Gulls and Atlantic Puffins that Ingested Prudhoe Bay Crude Oil |
title_sort |
clinical, gross, and histological findings in herring gulls and atlantic puffins that ingested prudhoe bay crude oil |
publisher |
SAGE Publications |
publishDate |
1986 |
url |
http://dx.doi.org/10.1177/030098588602300305 http://journals.sagepub.com/doi/pdf/10.1177/030098588602300305 |
genre |
Atlantic puffin Prudhoe Bay |
genre_facet |
Atlantic puffin Prudhoe Bay |
op_source |
Veterinary Pathology volume 23, issue 3, page 254-263 ISSN 0300-9858 1544-2217 |
op_rights |
http://journals.sagepub.com/page/policies/text-and-data-mining-license |
op_doi |
https://doi.org/10.1177/030098588602300305 |
container_title |
Veterinary Pathology |
container_volume |
23 |
container_issue |
3 |
container_start_page |
254 |
op_container_end_page |
263 |
_version_ |
1799476412094087168 |