Identification of a Novel Papillomavirus in a Northern Fulmar ( Fulmarus glacialis) With Viral Production in Cartilage
We report the identification of a novel papillomavirus, Fulmarus glacialis papillomavirus 1 (FgPV1), present within an interdigital foot mass of a Northern Fulmar ( Fulmarus glacialis). The mass of interest was composed of normal stratified and keratinized epithelium and dense mesenchymal cells with...
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crsagepubl:10.1177/0300985814542812 2024-09-09T19:40:48+00:00 Identification of a Novel Papillomavirus in a Northern Fulmar ( Fulmarus glacialis) With Viral Production in Cartilage Gaynor, A. M. Fish, S. Duerr, R. S. Cruz, F. N. Dela Pesavento, P. A. 2014 http://dx.doi.org/10.1177/0300985814542812 http://journals.sagepub.com/doi/pdf/10.1177/0300985814542812 http://journals.sagepub.com/doi/full-xml/10.1177/0300985814542812 en eng SAGE Publications http://journals.sagepub.com/page/policies/text-and-data-mining-license Veterinary Pathology volume 52, issue 3, page 553-561 ISSN 0300-9858 1544-2217 journal-article 2014 crsagepubl https://doi.org/10.1177/0300985814542812 2024-08-12T04:31:59Z We report the identification of a novel papillomavirus, Fulmarus glacialis papillomavirus 1 (FgPV1), present within an interdigital foot mass of a Northern Fulmar ( Fulmarus glacialis). The mass of interest was composed of normal stratified and keratinized epithelium and dense mesenchymal cells with central cartilaginous islands. Within the nuclei of many chondrocytes were loose aggregates or paracrystalline arrays of virions approximately 50 nm in size. Degenerate polymerase chain reaction was used to identify the virus as a putative papillomavirus, and the entire viral genome of 8132 base pairs was subsequently amplified and sequenced. Analysis revealed canonical papillomavirus architecture, including the early open reading frames E6, E7, E1, and E2 and the 2 late proteins L1 and L2. FgPV1 is most closely related to a cluster of avian and reptilian papillomaviruses as visualized by phylogenetic trees. This observation suggests that papillomavirus virion production can occur in mesenchymal cells. Article in Journal/Newspaper Fulmarus glacialis Northern Fulmar SAGE Publications Fulmar ENVELOPE(-46.016,-46.016,-60.616,-60.616) Veterinary Pathology 52 3 553 561 |
institution |
Open Polar |
collection |
SAGE Publications |
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crsagepubl |
language |
English |
description |
We report the identification of a novel papillomavirus, Fulmarus glacialis papillomavirus 1 (FgPV1), present within an interdigital foot mass of a Northern Fulmar ( Fulmarus glacialis). The mass of interest was composed of normal stratified and keratinized epithelium and dense mesenchymal cells with central cartilaginous islands. Within the nuclei of many chondrocytes were loose aggregates or paracrystalline arrays of virions approximately 50 nm in size. Degenerate polymerase chain reaction was used to identify the virus as a putative papillomavirus, and the entire viral genome of 8132 base pairs was subsequently amplified and sequenced. Analysis revealed canonical papillomavirus architecture, including the early open reading frames E6, E7, E1, and E2 and the 2 late proteins L1 and L2. FgPV1 is most closely related to a cluster of avian and reptilian papillomaviruses as visualized by phylogenetic trees. This observation suggests that papillomavirus virion production can occur in mesenchymal cells. |
format |
Article in Journal/Newspaper |
author |
Gaynor, A. M. Fish, S. Duerr, R. S. Cruz, F. N. Dela Pesavento, P. A. |
spellingShingle |
Gaynor, A. M. Fish, S. Duerr, R. S. Cruz, F. N. Dela Pesavento, P. A. Identification of a Novel Papillomavirus in a Northern Fulmar ( Fulmarus glacialis) With Viral Production in Cartilage |
author_facet |
Gaynor, A. M. Fish, S. Duerr, R. S. Cruz, F. N. Dela Pesavento, P. A. |
author_sort |
Gaynor, A. M. |
title |
Identification of a Novel Papillomavirus in a Northern Fulmar ( Fulmarus glacialis) With Viral Production in Cartilage |
title_short |
Identification of a Novel Papillomavirus in a Northern Fulmar ( Fulmarus glacialis) With Viral Production in Cartilage |
title_full |
Identification of a Novel Papillomavirus in a Northern Fulmar ( Fulmarus glacialis) With Viral Production in Cartilage |
title_fullStr |
Identification of a Novel Papillomavirus in a Northern Fulmar ( Fulmarus glacialis) With Viral Production in Cartilage |
title_full_unstemmed |
Identification of a Novel Papillomavirus in a Northern Fulmar ( Fulmarus glacialis) With Viral Production in Cartilage |
title_sort |
identification of a novel papillomavirus in a northern fulmar ( fulmarus glacialis) with viral production in cartilage |
publisher |
SAGE Publications |
publishDate |
2014 |
url |
http://dx.doi.org/10.1177/0300985814542812 http://journals.sagepub.com/doi/pdf/10.1177/0300985814542812 http://journals.sagepub.com/doi/full-xml/10.1177/0300985814542812 |
long_lat |
ENVELOPE(-46.016,-46.016,-60.616,-60.616) |
geographic |
Fulmar |
geographic_facet |
Fulmar |
genre |
Fulmarus glacialis Northern Fulmar |
genre_facet |
Fulmarus glacialis Northern Fulmar |
op_source |
Veterinary Pathology volume 52, issue 3, page 553-561 ISSN 0300-9858 1544-2217 |
op_rights |
http://journals.sagepub.com/page/policies/text-and-data-mining-license |
op_doi |
https://doi.org/10.1177/0300985814542812 |
container_title |
Veterinary Pathology |
container_volume |
52 |
container_issue |
3 |
container_start_page |
553 |
op_container_end_page |
561 |
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1809910249347350528 |