How the European eel ( Anguilla anguilla ) loses its skeletal framework across lifetime
European eels ( Anguilla anguilla ) undertake an impressive 5 000 km long migration from European fresh waters through the North Atlantic Ocean to the Sargasso Sea. Along with sexual maturation, the eel skeleton undergoes a remarkable morphological transformation during migration, where a hitherto c...
Published in: | Proceedings of the Royal Society B: Biological Sciences |
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crroyalsociety:10.1098/rspb.2016.1550 2024-06-02T07:55:09+00:00 How the European eel ( Anguilla anguilla ) loses its skeletal framework across lifetime Rolvien, Tim Nagel, Florian Milovanovic, Petar Wuertz, Sven Marshall, Robert Percy Jeschke, Anke Schmidt, Felix N. Hahn, Michael Witten, P. Eckhard Amling, Michael Busse, Björn PIER Deutsche Forschungsgemeinschaft 2016 http://dx.doi.org/10.1098/rspb.2016.1550 https://royalsocietypublishing.org/doi/pdf/10.1098/rspb.2016.1550 https://royalsocietypublishing.org/doi/full-xml/10.1098/rspb.2016.1550 en eng The Royal Society https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ Proceedings of the Royal Society B: Biological Sciences volume 283, issue 1841, page 20161550 ISSN 0962-8452 1471-2954 journal-article 2016 crroyalsociety https://doi.org/10.1098/rspb.2016.1550 2024-05-07T14:16:57Z European eels ( Anguilla anguilla ) undertake an impressive 5 000 km long migration from European fresh waters through the North Atlantic Ocean to the Sargasso Sea. Along with sexual maturation, the eel skeleton undergoes a remarkable morphological transformation during migration, where a hitherto completely obscure bone loss phenomenon occurs. To unravel mechanisms of the maturation-related decay of the skeleton, we performed a multiscale assessment of eels' bones at different life-cycle stages. Accordingly, the skeleton reflects extensive bone loss that is mediated via multinucleated bone-resorbing osteoclasts, while other resorption mechanisms such as osteocytic osteolysis or matrix demineralization were not observed. Preserving mechanical stability and releasing minerals for energy metabolism are two mutually exclusive functions of the skeleton that are orchestrated in eels through the presence of two spatially segregated hard tissues: cellular bone and acellular notochord. The cellular bone serves as a source of mineral release following osteoclastic resorption, whereas the mineralized notochord sheath, which is inaccessible for resorption processes due to an unmineralized cover layer, ensures sufficient mechanical stability as a part of the notochord sheath. Clearly, an eel's skeleton is structurally optimized to meet the metabolic challenge of fasting and simultaneous sexual development during an exhausting journey to spawning areas, while the function of the vertebral column is maintained to achieve this goal. Article in Journal/Newspaper Anguilla anguilla North Atlantic The Royal Society Proceedings of the Royal Society B: Biological Sciences 283 1841 20161550 |
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The Royal Society |
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crroyalsociety |
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English |
description |
European eels ( Anguilla anguilla ) undertake an impressive 5 000 km long migration from European fresh waters through the North Atlantic Ocean to the Sargasso Sea. Along with sexual maturation, the eel skeleton undergoes a remarkable morphological transformation during migration, where a hitherto completely obscure bone loss phenomenon occurs. To unravel mechanisms of the maturation-related decay of the skeleton, we performed a multiscale assessment of eels' bones at different life-cycle stages. Accordingly, the skeleton reflects extensive bone loss that is mediated via multinucleated bone-resorbing osteoclasts, while other resorption mechanisms such as osteocytic osteolysis or matrix demineralization were not observed. Preserving mechanical stability and releasing minerals for energy metabolism are two mutually exclusive functions of the skeleton that are orchestrated in eels through the presence of two spatially segregated hard tissues: cellular bone and acellular notochord. The cellular bone serves as a source of mineral release following osteoclastic resorption, whereas the mineralized notochord sheath, which is inaccessible for resorption processes due to an unmineralized cover layer, ensures sufficient mechanical stability as a part of the notochord sheath. Clearly, an eel's skeleton is structurally optimized to meet the metabolic challenge of fasting and simultaneous sexual development during an exhausting journey to spawning areas, while the function of the vertebral column is maintained to achieve this goal. |
author2 |
PIER Deutsche Forschungsgemeinschaft |
format |
Article in Journal/Newspaper |
author |
Rolvien, Tim Nagel, Florian Milovanovic, Petar Wuertz, Sven Marshall, Robert Percy Jeschke, Anke Schmidt, Felix N. Hahn, Michael Witten, P. Eckhard Amling, Michael Busse, Björn |
spellingShingle |
Rolvien, Tim Nagel, Florian Milovanovic, Petar Wuertz, Sven Marshall, Robert Percy Jeschke, Anke Schmidt, Felix N. Hahn, Michael Witten, P. Eckhard Amling, Michael Busse, Björn How the European eel ( Anguilla anguilla ) loses its skeletal framework across lifetime |
author_facet |
Rolvien, Tim Nagel, Florian Milovanovic, Petar Wuertz, Sven Marshall, Robert Percy Jeschke, Anke Schmidt, Felix N. Hahn, Michael Witten, P. Eckhard Amling, Michael Busse, Björn |
author_sort |
Rolvien, Tim |
title |
How the European eel ( Anguilla anguilla ) loses its skeletal framework across lifetime |
title_short |
How the European eel ( Anguilla anguilla ) loses its skeletal framework across lifetime |
title_full |
How the European eel ( Anguilla anguilla ) loses its skeletal framework across lifetime |
title_fullStr |
How the European eel ( Anguilla anguilla ) loses its skeletal framework across lifetime |
title_full_unstemmed |
How the European eel ( Anguilla anguilla ) loses its skeletal framework across lifetime |
title_sort |
how the european eel ( anguilla anguilla ) loses its skeletal framework across lifetime |
publisher |
The Royal Society |
publishDate |
2016 |
url |
http://dx.doi.org/10.1098/rspb.2016.1550 https://royalsocietypublishing.org/doi/pdf/10.1098/rspb.2016.1550 https://royalsocietypublishing.org/doi/full-xml/10.1098/rspb.2016.1550 |
genre |
Anguilla anguilla North Atlantic |
genre_facet |
Anguilla anguilla North Atlantic |
op_source |
Proceedings of the Royal Society B: Biological Sciences volume 283, issue 1841, page 20161550 ISSN 0962-8452 1471-2954 |
op_rights |
https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ |
op_doi |
https://doi.org/10.1098/rspb.2016.1550 |
container_title |
Proceedings of the Royal Society B: Biological Sciences |
container_volume |
283 |
container_issue |
1841 |
container_start_page |
20161550 |
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1800746249033351168 |