Metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish
Metabolic programming occurs when variations in nutrition during a specific developmental window result in long-term metabolic effects. It has been studied almost exclusively in humans and other mammals but never in an ecological context. Here, we report metabolic programming and its functional cons...
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crroyalsociety:10.1098/rspb.2015.1414 2024-09-09T20:05:09+00:00 Metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish Fuiman, Lee A. Perez, Kestrel O. Guy Harvey Ocean Foundation National Oceanic and Atmospheric Administration 2015 http://dx.doi.org/10.1098/rspb.2015.1414 https://royalsocietypublishing.org/doi/pdf/10.1098/rspb.2015.1414 https://royalsocietypublishing.org/doi/full-xml/10.1098/rspb.2015.1414 en eng The Royal Society https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ Proceedings of the Royal Society B: Biological Sciences volume 282, issue 1819, page 20151414 ISSN 0962-8452 1471-2954 journal-article 2015 crroyalsociety https://doi.org/10.1098/rspb.2015.1414 2024-08-19T04:24:53Z Metabolic programming occurs when variations in nutrition during a specific developmental window result in long-term metabolic effects. It has been studied almost exclusively in humans and other mammals but never in an ecological context. Here, we report metabolic programming and its functional consequences in a marine fish, red drum. We demonstrate that maternal provisioning of eggs with an essential fatty acid, docosahexaenoic acid (DHA), varies with DHA content of the maternal diet. When offspring are reared on a DHA-replete diet, whole-body DHA content of offspring depends upon the amount of DHA that was in the egg. We further demonstrate that whole-body DHA content is correlated with traits related to offspring fitness (escape responses, routine swimming, growth, and survival). DHA content of red drum eggs produced in nature is in the range where the effects of metabolic programming are most pronounced. Our findings indicate that during a brief developmental window, DHA plays a role in establishing the metabolic capacity for its own uptake or storage, with protracted and possibly permanent effects on ecologically important survival skills of individuals and important implications for dynamics of populations and food webs. Article in Journal/Newspaper Red drum The Royal Society Proceedings of the Royal Society B: Biological Sciences 282 1819 20151414 |
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English |
description |
Metabolic programming occurs when variations in nutrition during a specific developmental window result in long-term metabolic effects. It has been studied almost exclusively in humans and other mammals but never in an ecological context. Here, we report metabolic programming and its functional consequences in a marine fish, red drum. We demonstrate that maternal provisioning of eggs with an essential fatty acid, docosahexaenoic acid (DHA), varies with DHA content of the maternal diet. When offspring are reared on a DHA-replete diet, whole-body DHA content of offspring depends upon the amount of DHA that was in the egg. We further demonstrate that whole-body DHA content is correlated with traits related to offspring fitness (escape responses, routine swimming, growth, and survival). DHA content of red drum eggs produced in nature is in the range where the effects of metabolic programming are most pronounced. Our findings indicate that during a brief developmental window, DHA plays a role in establishing the metabolic capacity for its own uptake or storage, with protracted and possibly permanent effects on ecologically important survival skills of individuals and important implications for dynamics of populations and food webs. |
author2 |
Guy Harvey Ocean Foundation National Oceanic and Atmospheric Administration |
format |
Article in Journal/Newspaper |
author |
Fuiman, Lee A. Perez, Kestrel O. |
spellingShingle |
Fuiman, Lee A. Perez, Kestrel O. Metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish |
author_facet |
Fuiman, Lee A. Perez, Kestrel O. |
author_sort |
Fuiman, Lee A. |
title |
Metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish |
title_short |
Metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish |
title_full |
Metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish |
title_fullStr |
Metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish |
title_full_unstemmed |
Metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish |
title_sort |
metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish |
publisher |
The Royal Society |
publishDate |
2015 |
url |
http://dx.doi.org/10.1098/rspb.2015.1414 https://royalsocietypublishing.org/doi/pdf/10.1098/rspb.2015.1414 https://royalsocietypublishing.org/doi/full-xml/10.1098/rspb.2015.1414 |
genre |
Red drum |
genre_facet |
Red drum |
op_source |
Proceedings of the Royal Society B: Biological Sciences volume 282, issue 1819, page 20151414 ISSN 0962-8452 1471-2954 |
op_rights |
https://royalsociety.org/journals/ethics-policies/data-sharing-mining/ |
op_doi |
https://doi.org/10.1098/rspb.2015.1414 |
container_title |
Proceedings of the Royal Society B: Biological Sciences |
container_volume |
282 |
container_issue |
1819 |
container_start_page |
20151414 |
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1809937464885772288 |